{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nitric+oxide+supplement",
    "query": {
      "intervention": "Nitric oxide supplement"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 34,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nitric+oxide+supplement&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-08T15:16:58.278Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03064048",
      "title": "Nitric Oxide Supplementation on Neurocognitive Functions in Patients With ASLD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Argininosuccinate Lyase Deficiency",
        "Urea Cycle Disorder",
        "Urea Cycle Disorders, Inborn",
        "Argininosuccinic Aciduria"
      ],
      "interventions": [
        {
          "name": "Neo-ASA",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "6 Years to 50 Years"
      },
      "enrollment_count": 16,
      "start_date": "2017-09-15",
      "completion_date": "2023-01-31",
      "has_results": false,
      "last_update_posted_date": "2023-02-27",
      "last_synced_at": "2026-09-08T15:16:58.278Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03064048"
    },
    {
      "nct_id": "NCT00043719",
      "title": "Nitroglycerin Ointment for Preventing Bone Loss in Postmenopausal Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Osteoporosis",
        "Osteopenia"
      ],
      "interventions": [
        {
          "name": "Nitroglycerin ointment",
          "type": "DRUG"
        },
        {
          "name": "Calcium supplement with vitamin D",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 65 Years · Female only"
      },
      "enrollment_count": 200,
      "start_date": "2002-07",
      "completion_date": "2007-12",
      "has_results": false,
      "last_update_posted_date": "2009-02-02",
      "last_synced_at": "2026-09-08T15:16:58.278Z",
      "location_count": 1,
      "location_summary": "New Brunswick, New Jersey",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00043719"
    },
    {
      "nct_id": "NCT06672952",
      "title": "Dose-Response Impact of Glucosyl-Hesperidin (CitraPeak) on Exercise Performance, Blood Flow, Stress, Cognition, and Other Perceptual Indicators",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Exercise Performance",
        "Exercise Recovery",
        "Cognitive Function",
        "Nitric Oxide",
        "Blood Flow",
        "Endurance Exercise"
      ],
      "interventions": [
        {
          "name": "400 mg CITRAPEAK® (glucosyl-hesperidin) supplementation",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "200 mg CITRAPEAK® (glucosyl-hesperidin) supplementation",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Lindenwood University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 60,
      "start_date": "2025-04-15",
      "completion_date": "2026-01-01",
      "has_results": false,
      "last_update_posted_date": "2025-12-12",
      "last_synced_at": "2026-09-08T15:16:58.278Z",
      "location_count": 1,
      "location_summary": "Saint Charles, Missouri",
      "locations": [
        {
          "city": "Saint Charles",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06672952"
    },
    {
      "nct_id": "NCT03289481",
      "title": "Treatment of HFpEF With Nitrate Supplement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Heart Failure With Normal Ejection Fraction"
      ],
      "interventions": [
        {
          "name": "Active lozenge",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "DRUG"
      ],
      "sponsor": "MaineHealth",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 13,
      "start_date": "2017-06-29",
      "completion_date": "2018-08-22",
      "has_results": true,
      "last_update_posted_date": "2021-10-06",
      "last_synced_at": "2026-09-08T15:16:58.278Z",
      "location_count": 1,
      "location_summary": "Rockport, Maine",
      "locations": [
        {
          "city": "Rockport",
          "state": "Maine"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03289481"
    },
    {
      "nct_id": "NCT03159273",
      "title": "Nitrate Supplementation During Final Examination Stress",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Airway Disease"
      ],
      "interventions": [
        {
          "name": "Beetroot Juice Group",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Southern Methodist University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 76,
      "start_date": "2014-01",
      "completion_date": "2015-05",
      "has_results": false,
      "last_update_posted_date": "2018-05-23",
      "last_synced_at": "2026-09-08T15:16:58.278Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03159273"
    },
    {
      "nct_id": "NCT06434181",
      "title": "Beetroot Juice for Boosting Immunity During a Time of Stress.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Beetroot Juice",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo Control",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Baylor University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 114,
      "start_date": "2022-04-11",
      "completion_date": "2022-12-13",
      "has_results": false,
      "last_update_posted_date": "2024-05-30",
      "last_synced_at": "2026-09-08T15:16:58.278Z",
      "location_count": 2,
      "location_summary": "Dallas, Texas • Waco, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        },
        {
          "city": "Waco",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06434181"
    },
    {
      "nct_id": "NCT03631394",
      "title": "The Effects of Dietary Nitric Oxide and Anthocyanins on Anaerobic Exercise Performance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Exercise"
      ],
      "interventions": [
        {
          "name": "beetroot and anthocyanin",
          "type": "OTHER"
        },
        {
          "name": "beetroot and placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "21 Years to 35 Years"
      },
      "enrollment_count": 28,
      "start_date": "2018-09-01",
      "completion_date": "2019-04-01",
      "has_results": false,
      "last_update_posted_date": "2019-05-15",
      "last_synced_at": "2026-09-08T15:16:58.278Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03631394"
    },
    {
      "nct_id": "NCT07216755",
      "title": "Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Adults",
        "Mechanical Ventilation Dependence",
        "Hypoxia",
        "Exercise Training",
        "Exercise Intolerance",
        "Dietary Supplement",
        "Nitrate Supplementation",
        "Inspiratory Muscle Training"
      ],
      "interventions": [
        {
          "name": "Respiratory Muscle Training (RMT)",
          "type": "DEVICE"
        },
        {
          "name": "Sham Respiratory Muscle Training",
          "type": "DEVICE"
        },
        {
          "name": "Dietary Supplement: Beetroot Juice Concentrate",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "placebo beverage",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Embry-Riddle Aeronautical University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 80,
      "start_date": "2025-09-01",
      "completion_date": "2028-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-15",
      "last_synced_at": "2026-09-08T15:16:58.278Z",
      "location_count": 1,
      "location_summary": "Daytona Beach, Florida",
      "locations": [
        {
          "city": "Daytona Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07216755"
    },
    {
      "nct_id": "NCT03566524",
      "title": "Study of Arginine and Nitric Oxide in Patients With Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ketosis Prone Diabetes"
      ],
      "interventions": [
        {
          "name": "Citrulline",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Alanine",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "20 Years to 65 Years"
      },
      "enrollment_count": 10,
      "start_date": "2018-07-01",
      "completion_date": "2022-06-30",
      "has_results": false,
      "last_update_posted_date": "2022-07-29",
      "last_synced_at": "2026-09-08T15:16:58.278Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03566524"
    },
    {
      "nct_id": "NCT07747714",
      "title": "Black Forest Cocoa Flavanol Supplementation and Health Trial",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Endothelial Function",
        "Oxidative Stress",
        "Inflamation",
        "Vascular Health"
      ],
      "interventions": [
        {
          "name": "Cocoa Flavanol Supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Low-Flavanol Control Powder",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "The Black Forest LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "75 Years",
        "sex": "MALE",
        "summary": "30 Years to 75 Years · Male only"
      },
      "enrollment_count": 90,
      "start_date": "2026-08-15",
      "completion_date": "2027-01",
      "has_results": false,
      "last_update_posted_date": "2026-08-05",
      "last_synced_at": "2026-09-08T15:16:58.278Z",
      "location_count": 2,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07747714"
    }
  ]
}