{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Non+invasive+Ventilation+%28NIV%29",
    "query": {
      "intervention": "Non invasive Ventilation (NIV)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 76,
    "total_pages": 8,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Non+invasive+Ventilation+%28NIV%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-30T21:08:42.341Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02865343",
      "title": "Ventilatory Support to Improve Exercise Training in High Level Spinal Cord Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injury"
      ],
      "interventions": [
        {
          "name": "Non-invasive Ventilation(NIV)",
          "type": "DEVICE"
        },
        {
          "name": "Sham Non-invasive ventilation(NIV)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Spaulding Rehabilitation Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 11,
      "start_date": "2017-02-22",
      "completion_date": "2019-06-28",
      "has_results": true,
      "last_update_posted_date": "2023-02-09",
      "last_synced_at": "2026-09-30T21:08:42.341Z",
      "location_count": 1,
      "location_summary": "Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02865343"
    },
    {
      "nct_id": "NCT02680639",
      "title": "The Use of High Frequency Oscillations With NIV in Hypercapnic COPD Participants",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease"
      ],
      "interventions": [
        {
          "name": "BiPAP Synchrony ventilator",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Philips Respironics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "21 Years to 85 Years"
      },
      "enrollment_count": 10,
      "start_date": "2015-11-13",
      "completion_date": "2016-08-24",
      "has_results": true,
      "last_update_posted_date": "2019-05-06",
      "last_synced_at": "2026-09-30T21:08:42.341Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02680639"
    },
    {
      "nct_id": "NCT01368614",
      "title": "AVAPS-AE Efficacy Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity Hypoventilation Syndrome"
      ],
      "interventions": [
        {
          "name": "AVAPS-AE Mode of Therapy",
          "type": "DEVICE"
        },
        {
          "name": "Respironics OnmiLab BiPAP S mode",
          "type": "DEVICE"
        },
        {
          "name": "Respironics OmniLab Advanced CPAP mode",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Philips Respironics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 90,
      "start_date": "2011-09-12",
      "completion_date": "2013-05-30",
      "has_results": true,
      "last_update_posted_date": "2019-04-26",
      "last_synced_at": "2026-09-30T21:08:42.341Z",
      "location_count": 2,
      "location_summary": "Tucson, Arizona • Chicago, Illinois",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01368614"
    },
    {
      "nct_id": "NCT02158923",
      "title": "Individualized Perioperative Open Lung Ventilatory Strategy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Moderated-high Risk of Postoperative Pulmonary Complication",
        "Abdominal Surgery Expected More Than Two Hours"
      ],
      "interventions": [
        {
          "name": "Alveolar recruitment maneuver",
          "type": "PROCEDURE"
        },
        {
          "name": "Calculation of optimal PEEP",
          "type": "PROCEDURE"
        },
        {
          "name": "Postoperative CPAP",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Fundación para la Investigación del Hospital Clínico de Valencia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 920,
      "start_date": "2014-09",
      "completion_date": "2016-04",
      "has_results": false,
      "last_update_posted_date": "2016-05-17",
      "last_synced_at": "2026-09-30T21:08:42.341Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02158923"
    },
    {
      "nct_id": "NCT02788110",
      "title": "Work of Breathing During Non-invasive Ventilation in Premature Neonates",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress Syndrome, Newborn",
        "Bronchopulmonary Dysplasia"
      ],
      "interventions": [
        {
          "name": "Noninvasive neurally adjusted ventilatory assist (NIV NAVA)",
          "type": "OTHER"
        },
        {
          "name": "Nasal intermittent positive pressure ventilation (NIPPV)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Arkansas Children's Hospital Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "Up to 12 Months"
      },
      "enrollment_count": 15,
      "start_date": "2016-08",
      "completion_date": "2018-06",
      "has_results": false,
      "last_update_posted_date": "2019-01-11",
      "last_synced_at": "2026-09-30T21:08:42.341Z",
      "location_count": 1,
      "location_summary": "Little Rock, Arkansas",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02788110"
    },
    {
      "nct_id": "NCT04507425",
      "title": "High Flow Nasal Cannula With Noninvasive Ventilation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "Standard of Care - Nasal Cannula",
          "type": "OTHER"
        },
        {
          "name": "High-flow nasal cannula",
          "type": "OTHER"
        },
        {
          "name": "HFNC plus non-invasive ventilation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 6,
      "start_date": "2020-09-01",
      "completion_date": "2023-07-10",
      "has_results": false,
      "last_update_posted_date": "2023-11-21",
      "last_synced_at": "2026-09-30T21:08:42.341Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04507425"
    },
    {
      "nct_id": "NCT06578468",
      "title": "End-Tidal Oxygen for Intubation in the Emergency Department",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critical Illness",
        "Hypoxia",
        "Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "End-tidal oxygen monitor",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sydney Local Health District",
      "sponsor_class": "OTHER_GOV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1400,
      "start_date": "2024-08-05",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-09-30T21:08:42.341Z",
      "location_count": 3,
      "location_summary": "Minneapolis, Minnesota • Albuquerque, New Mexico • The Bronx, New York",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06578468"
    },
    {
      "nct_id": "NCT03795753",
      "title": "Determining the Benefits of Improving Communication in BPAP/CPAP Users",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Positive-Pressure Respiration",
        "Communication"
      ],
      "interventions": [
        {
          "name": "F2S Communicator",
          "type": "DEVICE"
        },
        {
          "name": "Non-functioning Communicator",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2019-03-22",
      "completion_date": "2019-07-08",
      "has_results": true,
      "last_update_posted_date": "2020-09-18",
      "last_synced_at": "2026-09-30T21:08:42.341Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03795753"
    },
    {
      "nct_id": "NCT03298035",
      "title": "A Comparison of Non-invasive Ventilation Methods Used to Prevent Endotracheal Intubation Due to Apnea in Very Low Birth Weight Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Apnea of Prematurity"
      ],
      "interventions": [
        {
          "name": "NCPAP as mode for apnea prevention",
          "type": "DEVICE"
        },
        {
          "name": "NIPPV as rescue mode for apnea prevention",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 19,
      "start_date": "2017-11-11",
      "completion_date": "2018-12-31",
      "has_results": true,
      "last_update_posted_date": "2020-02-07",
      "last_synced_at": "2026-09-30T21:08:42.341Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03298035"
    },
    {
      "nct_id": "NCT02896751",
      "title": "Use of a 3D Printer to Make Custom Sleep Masks for Positive Airway Pressure Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Apnea",
        "Pediatric Sleep Apnea"
      ],
      "interventions": [
        {
          "name": "3D printed NIV mask",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "5 Years to 25 Years"
      },
      "enrollment_count": 15,
      "start_date": "2016-08",
      "completion_date": "2022-03-07",
      "has_results": false,
      "last_update_posted_date": "2025-10-03",
      "last_synced_at": "2026-09-30T21:08:42.341Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02896751"
    }
  ]
}