{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Non+steroidal+anti-inflammatory+drug+and+opioids&page=2", "query": { "intervention": "Non steroidal anti-inflammatory drug and opioids", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 31, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Non+steroidal+anti-inflammatory+drug+and+opioids&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Non+steroidal+anti-inflammatory+drug+and+opioids&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-11T18:53:50.989Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05722002", "title": "Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Surgery", "Pain, Postoperative" ], "interventions": [ { "name": "NSAID", "type": "DRUG" }, { "name": "Opioid", "type": "DRUG" }, { "name": "Acetaminophen", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Michigan", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 900, "start_date": "2023-02-06", "completion_date": "2027-08-31", "has_results": false, "last_update_posted_date": "2026-08-28", "last_synced_at": "2026-10-11T18:53:50.989Z", "location_count": 6, "location_summary": "Ann Arbor, Michigan • Detroit, Michigan • St Louis, Missouri + 3 more", "locations": [ { "city": "Ann Arbor", "state": "Michigan" }, { "city": "Detroit", "state": "Michigan" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Camden", "state": "New Jersey" }, { "city": "Chapel Hill", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT05722002" }, { "nct_id": "NCT04766996", "title": "PROUD Study - Preventing Opioid Use Disorders", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Anesthesia", "Opioid Use" ], "interventions": [ { "name": "Guided mindfulness exercises", "type": "BEHAVIORAL" }, { "name": "Self-administered aromatherapy", "type": "OTHER" }, { "name": "Baby aspirin", "type": "DRUG" }, { "name": "Tylenol/Acetaminophen", "type": "DRUG" }, { "name": "Pregabalin", "type": "DRUG" }, { "name": "Prednisone", "type": "DRUG" }, { "name": "Meloxicam", "type": "DRUG" }, { "name": "Prilosec", "type": "DRUG" }, { "name": "Tramadol", "type": "DRUG" }, { "name": "Voltaren", "type": "DRUG" }, { "name": "Zofran", "type": "DRUG" }, { "name": "Pepcid", "type": "DRUG" }, { "name": "Reglan", "type": "DRUG" }, { "name": "Versed", "type": "DRUG" }, { "name": "Lidocaine", "type": "DRUG" }, { "name": "Propofol", "type": "DRUG" }, { "name": "Ancef", "type": "DRUG" }, { "name": "Tranexamic Acid (TXA)", "type": "DRUG" }, { "name": "Decadron", "type": "DRUG" }, { "name": "Bupivacaine hydrochloride", "type": "DRUG" }, { "name": "Toradol", "type": "DRUG" } ], "intervention_types": [ "BEHAVIORAL", "OTHER", "DRUG" ], "sponsor": "Emory University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 57, "start_date": "2021-05-17", "completion_date": "2021-12-27", "has_results": true, "last_update_posted_date": "2023-06-22", "last_synced_at": "2026-10-11T18:53:50.989Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT04766996" }, { "nct_id": "NCT03794882", "title": "Impact of Quadratus Lumborum Block on Recovery Profile After Ventral Hernia Repair", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Pain, Postoperative", "Opioid Use" ], "interventions": [ { "name": "Quadratus Lumborum Block", "type": "COMBINATION_PRODUCT" }, { "name": "Standard Medical Management", "type": "PROCEDURE" } ], "intervention_types": [ "COMBINATION_PRODUCT", "PROCEDURE" ], "sponsor": "University of Wisconsin, Madison", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 14, "start_date": "2019-05-06", "completion_date": "2020-03-12", "has_results": true, "last_update_posted_date": "2022-09-21", "last_synced_at": "2026-10-11T18:53:50.989Z", "location_count": 1, "location_summary": "Madison, Wisconsin", "locations": [ { "city": "Madison", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT03794882" }, { "nct_id": "NCT06201676", "title": "Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Orthopaedic Trauma", "Chronic Opioid Use" ], "interventions": [ { "name": "Ketorolac Injection", "type": "DRUG" }, { "name": "Standard of Care (SOC) Multimodal Analgesia", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 458, "start_date": "2025-02-28", "completion_date": "2027-08-31", "has_results": false, "last_update_posted_date": "2026-05-14", "last_synced_at": "2026-10-11T18:53:50.989Z", "location_count": 2, "location_summary": "Boston, Massachusetts • Nashville, Tennessee", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT06201676" }, { "nct_id": "NCT01507220", "title": "A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Bowel Obstruction" ], "interventions": [ { "name": "morphine sulfate", "type": "DRUG" }, { "name": "bupivacaine liposome extended-release injectable suspension", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pacira Pharmaceuticals, Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 2, "start_date": "2012-03", "completion_date": "2012-07", "has_results": true, "last_update_posted_date": "2014-03-06", "last_synced_at": "2026-10-11T18:53:50.989Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01507220" }, { "nct_id": "NCT02091297", "title": "Comparison of Different Methods of Pain Control After Cesarean Section for Patients on Buprenorphine or Methadone", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Caesarean Delivery" ], "interventions": [ { "name": "TAP Block", "type": "DRUG" }, { "name": "Ropivacaine", "type": "DRUG" }, { "name": "Acetaminophen", "type": "DRUG" }, { "name": "Morphine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Dartmouth-Hitchcock Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 0, "start_date": "2014-04", "completion_date": "2014-04", "has_results": false, "last_update_posted_date": "2016-08-05", "last_synced_at": "2026-10-11T18:53:50.989Z", "location_count": 3, "location_summary": "Boston, Massachusetts • Lebanon, New Hampshire", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Lebanon", "state": "New Hampshire" } ], "official_url": "https://clinicaltrials.gov/study/NCT02091297" }, { "nct_id": "NCT05332314", "title": "NSAIDS vs Opioids in Tibial Fractures", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Trauma" ], "interventions": [ { "name": "NSAIDs", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Louisville", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "105 Years", "sex": "ALL", "summary": "18 Years to 105 Years" }, "enrollment_count": 100, "start_date": "2019-11-12", "completion_date": "2025-05-30", "has_results": false, "last_update_posted_date": "2022-04-18", "last_synced_at": "2026-10-11T18:53:50.989Z", "location_count": 2, "location_summary": "Louisville, Kentucky", "locations": [ { "city": "Louisville", "state": "Kentucky" }, { "city": "Louisville", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT05332314" }, { "nct_id": "NCT05642026", "title": "INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib Fractures", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Rib Fractures" ], "interventions": [ { "name": "Ropivacaine", "type": "DRUG" }, { "name": "Non steroidal anti-inflammatory drug and opioids", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Zachary Warriner", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 180, "start_date": "2025-09-23", "completion_date": "2027-02-01", "has_results": false, "last_update_posted_date": "2025-10-07", "last_synced_at": "2026-10-11T18:53:50.989Z", "location_count": 1, "location_summary": "Lexington, Kentucky", "locations": [ { "city": "Lexington", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT05642026" }, { "nct_id": "NCT02625155", "title": "Standard of Care Versus Urine Testing With Selective PHarmacogenomics for Effective Drug and Dosing REgimens", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Target Drug-related Adverse Events" ], "interventions": [ { "name": "Urine diagnostic testing as SOC, drug regimen changes per SOC", "type": "OTHER" }, { "name": "Urine diagnostic testing with selective PGx testing, drug regimen changes based on PGx test results", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "InSource Diagnostics", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 14000, "start_date": "2015-12", "completion_date": null, "has_results": false, "last_update_posted_date": "2018-02-28", "last_synced_at": "2026-10-11T18:53:50.989Z", "location_count": 1, "location_summary": "Tazewell, Tennessee", "locations": [ { "city": "Tazewell", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT02625155" }, { "nct_id": "NCT06671002", "title": "Comparing Analgesic Regimen Effectiveness and Safety for Surgery for Kids Trial", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Surgery", "Pain, Post Operative" ], "interventions": [ { "name": "NSAID", "type": "DRUG" }, { "name": "Opioid", "type": "DRUG" }, { "name": "Acetaminophen", "type": "DRUG" }, { "name": "Ibuprofen", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Michigan", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "20 Years", "sex": "ALL", "summary": "12 Years to 20 Years" }, "enrollment_count": 900, "start_date": "2025-01-10", "completion_date": "2027-10-31", "has_results": false, "last_update_posted_date": "2026-03-04", "last_synced_at": "2026-10-11T18:53:50.989Z", "location_count": 4, "location_summary": "Los Angeles, California • Palo Alto, California • Ann Arbor, Michigan + 1 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Ann Arbor", "state": "Michigan" }, { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT06671002" } ] }