{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Non-Invasive+Infrared+Spectroscopy",
    "query": {
      "intervention": "Non-Invasive Infrared Spectroscopy"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 48,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Non-Invasive+Infrared+Spectroscopy&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-05T17:40:54.062Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02741648",
      "title": "RBC Irradiation, Anemia and Gut Injury",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Anemia",
        "Necrotizing Enterocolitis"
      ],
      "interventions": [
        {
          "name": "Near Infrared Spectroscopy",
          "type": "DEVICE"
        },
        {
          "name": "Non-invasive Image-based Anemia Assessment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "5 Days",
        "sex": "ALL",
        "summary": "1 Day to 5 Days"
      },
      "enrollment_count": 324,
      "start_date": "2016-07",
      "completion_date": "2026-02-19",
      "has_results": false,
      "last_update_posted_date": "2026-06-02",
      "last_synced_at": "2026-09-05T17:40:54.062Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02741648"
    },
    {
      "nct_id": "NCT07044596",
      "title": "Non-invasive Stimulation of the Glymphatic System for Slowing Cognitive Decline",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Traumatic Brain Injury",
        "Post Concussion Syndrome"
      ],
      "interventions": [
        {
          "name": "Functional near-infrared spectroscopy (fNIRS)",
          "type": "DEVICE"
        },
        {
          "name": "V1 stimulation electrodes",
          "type": "DEVICE"
        },
        {
          "name": "Magnetic Resonance Imaging (MRI)",
          "type": "DEVICE"
        },
        {
          "name": "MAGNUS scanner",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "20 Years to 85 Years"
      },
      "enrollment_count": 55,
      "start_date": "2025-11-13",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-05-06",
      "last_synced_at": "2026-09-05T17:40:54.062Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07044596"
    },
    {
      "nct_id": "NCT05916417",
      "title": "TMS-fNIRS Personalized Dosing",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post Traumatic Stress Disorder",
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "TMS-fNIRS over the dl-PFC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Florida State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 60,
      "start_date": "2024-01-19",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-18",
      "last_synced_at": "2026-09-05T17:40:54.062Z",
      "location_count": 1,
      "location_summary": "Tallahassee, Florida",
      "locations": [
        {
          "city": "Tallahassee",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05916417"
    },
    {
      "nct_id": "NCT01812109",
      "title": "Near-Infrared Spectroscopy for Pediatric Acute Scrotum and Testicular Torsion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Scrotum",
        "Testicular Torsion"
      ],
      "interventions": [
        {
          "name": "Hutchison Technologies Inspectra StO2 SpotCheck Near-Infrared Spectroscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "21 Years",
        "sex": "MALE",
        "summary": "1 Month to 21 Years · Male only"
      },
      "enrollment_count": 154,
      "start_date": "2011-03-24",
      "completion_date": "2015-11-09",
      "has_results": true,
      "last_update_posted_date": "2024-05-24",
      "last_synced_at": "2026-09-05T17:40:54.062Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01812109"
    },
    {
      "nct_id": "NCT01425385",
      "title": "Autoregulation Assessment During Liver Transplantation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Liver Failure",
        "Liver Transplantation",
        "Encephalopathy"
      ],
      "interventions": [
        {
          "name": "Near infrared spectroscopy monitoring",
          "type": "OTHER"
        },
        {
          "name": "Autoregulation monitoring",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2011-09",
      "completion_date": "2012-09",
      "has_results": false,
      "last_update_posted_date": "2017-08-22",
      "last_synced_at": "2026-09-05T17:40:54.062Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01425385"
    },
    {
      "nct_id": "NCT02887755",
      "title": "Assessing the Feasibility of a Novel Non-Invasive Sensor for Guiding Wounded Warrior Rehabilitation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rehabilitation Post-amputation"
      ],
      "interventions": [
        {
          "name": "Near-Infrared Spectroscopy (NIRS) Sensor",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Henry M. Jackson Foundation for the Advancement of Military Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 20,
      "start_date": "2015-12",
      "completion_date": "2017-10",
      "has_results": false,
      "last_update_posted_date": "2018-04-02",
      "last_synced_at": "2026-09-05T17:40:54.062Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02887755"
    },
    {
      "nct_id": "NCT05604547",
      "title": "Exploring Near Infrared Spectroscopy (NIRS) Technologies for Assessment of Muscle Physiology, Tissue Oxygenation, and Blood Flow in Patients With Sickle Cell Disease (SCD)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "SCD"
      ],
      "interventions": [
        {
          "name": "Non-Invasive Infrared Spectroscopy",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 49,
      "start_date": "2022-11-28",
      "completion_date": "2025-01-24",
      "has_results": false,
      "last_update_posted_date": "2025-08-01",
      "last_synced_at": "2026-09-05T17:40:54.062Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05604547"
    },
    {
      "nct_id": "NCT07294924",
      "title": "Prediction of REsponse to Depression Interventions (Accelerated rTMS) Using Clinical and TD-fNIRS Measurements",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Major Depressive Disorder (MDD)",
        "fNIRS"
      ],
      "interventions": [
        {
          "name": "fNIRS measurement",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Kernel",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 100,
      "start_date": "2026-01-01",
      "completion_date": "2026-12-15",
      "has_results": false,
      "last_update_posted_date": "2026-08-05",
      "last_synced_at": "2026-09-05T17:40:54.062Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California • Sunnyvale, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sunnyvale",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07294924"
    },
    {
      "nct_id": "NCT06852300",
      "title": "Sport-Related Concussion Recovery in Athletes",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Concussion Mild",
        "Concussion, Brain"
      ],
      "interventions": [
        {
          "name": "Concussion Assessment Battery",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Central Arkansas",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "26 Years",
        "sex": "ALL",
        "summary": "18 Years to 26 Years"
      },
      "enrollment_count": 1000,
      "start_date": "2016-04-11",
      "completion_date": "2030-05",
      "has_results": false,
      "last_update_posted_date": "2025-03-06",
      "last_synced_at": "2026-09-05T17:40:54.062Z",
      "location_count": 1,
      "location_summary": "Conway, Arkansas",
      "locations": [
        {
          "city": "Conway",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06852300"
    },
    {
      "nct_id": "NCT03060369",
      "title": "BWH Critical Care Study of CareGuide for Evaluation of Emerging or Established Shock",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Shock"
      ],
      "interventions": [
        {
          "name": "CareGuide™ device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2012-06",
      "completion_date": "2017-02",
      "has_results": false,
      "last_update_posted_date": "2017-02-23",
      "last_synced_at": "2026-09-05T17:40:54.062Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03060369"
    }
  ]
}