{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Non-Nicotine+Electronic+Cigarette&page=3",
    "query": {
      "intervention": "Non-Nicotine Electronic Cigarette",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 74,
    "total_pages": 8,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Non-Nicotine+Electronic+Cigarette&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Non-Nicotine+Electronic+Cigarette&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-03T10:50:24.168Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01867411",
      "title": "Multimodal Neuroimaging Genetic Biomarkers of Nicotine AddictionSeverity",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute on Drug Abuse (NIDA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 159,
      "start_date": "2013-11-06",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2026-09-24",
      "last_synced_at": "2026-10-03T10:50:24.168Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01867411"
    },
    {
      "nct_id": "NCT07172438",
      "title": "A RCT to Determine the Effect of ENDS Flavor Availability on Abstinence Within Smokers",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "Tobacco"
      ],
      "interventions": [
        {
          "name": "P2611222",
          "type": "OTHER"
        },
        {
          "name": "P2615022",
          "type": "OTHER"
        },
        {
          "name": "P2615122",
          "type": "OTHER"
        },
        {
          "name": "P2613422",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "RAI Services Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 668,
      "start_date": "2025-09-17",
      "completion_date": "2026-01-14",
      "has_results": false,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-10-03T10:50:24.168Z",
      "location_count": 27,
      "location_summary": "Chandler, Arizona • Fort Smith, Arkansas • Altamonte Springs, Florida + 21 more",
      "locations": [
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Fort Smith",
          "state": "Arkansas"
        },
        {
          "city": "Altamonte Springs",
          "state": "Florida"
        },
        {
          "city": "Clearwater",
          "state": "Florida"
        },
        {
          "city": "Maitland",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07172438"
    },
    {
      "nct_id": "NCT03625986",
      "title": "Does Switching to Nicotine Containing Electronic Cigarettes Reduce Health Risk Markers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Dependence"
      ],
      "interventions": [
        {
          "name": "Nicotine-Containing Electronic Cigarette",
          "type": "OTHER"
        },
        {
          "name": "Non-Nicotine Electronic Cigarette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 105,
      "start_date": "2022-04-22",
      "completion_date": "2024-02-23",
      "has_results": true,
      "last_update_posted_date": "2025-03-27",
      "last_synced_at": "2026-10-03T10:50:24.168Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03625986"
    },
    {
      "nct_id": "NCT06944847",
      "title": "Vaping and Smoking Project in People With Schizophrenia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Abstinence From Cigarettes vs E-cigarettes (ENDS)"
      ],
      "interventions": [
        {
          "name": "Acute (24-hour) abstinence",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Ad libitum smoking/vaping",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "State University of New York at Buffalo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "21 Years to 50 Years"
      },
      "enrollment_count": 64,
      "start_date": "2025-02-15",
      "completion_date": "2027-04-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-09",
      "last_synced_at": "2026-10-03T10:50:24.168Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06944847"
    },
    {
      "nct_id": "NCT07210268",
      "title": "Temporal Interference Methods for Addiction Treatment",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Use Disorder",
        "Substance Use Disorders"
      ],
      "interventions": [
        {
          "name": "TI-NDBS",
          "type": "DEVICE"
        },
        {
          "name": "Sham TI-NDBS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "21 Years to 50 Years"
      },
      "enrollment_count": 120,
      "start_date": "2026-01-22",
      "completion_date": "2027-02-27",
      "has_results": false,
      "last_update_posted_date": "2026-09-11",
      "last_synced_at": "2026-10-03T10:50:24.168Z",
      "location_count": 2,
      "location_summary": "Bloomington, Indiana • Indianapolis, Indiana",
      "locations": [
        {
          "city": "Bloomington",
          "state": "Indiana"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07210268"
    },
    {
      "nct_id": "NCT04143256",
      "title": "Evaluating Selected Constituents in the Exhaled Breath Samples",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarette Use",
        "Cigarette Use, Electronic",
        "Tobacco Use",
        "Tobacco Smoking"
      ],
      "interventions": [
        {
          "name": "JUUL ENDS 5% Virginia Tobacco",
          "type": "OTHER"
        },
        {
          "name": "JUUL 3% Virginia Tobacco ENDS",
          "type": "OTHER"
        },
        {
          "name": "JUUL 5% Mint ENDS",
          "type": "OTHER"
        },
        {
          "name": "JUUL 3% Mint ENDS",
          "type": "OTHER"
        },
        {
          "name": "JUUL 5% Menthol ENDS",
          "type": "OTHER"
        },
        {
          "name": "JUUL 3% Menthol ENDS",
          "type": "OTHER"
        },
        {
          "name": "JUUL 5% Mango ENDS",
          "type": "OTHER"
        },
        {
          "name": "JUUL 3% Mango ENDS",
          "type": "OTHER"
        },
        {
          "name": "US Cigarette, Non-menthol - Marlboro Gold King Size",
          "type": "OTHER"
        },
        {
          "name": "US Cigarette, Menthol - Newport King Size",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Juul Labs, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 135,
      "start_date": "2019-10-03",
      "completion_date": "2019-12-13",
      "has_results": false,
      "last_update_posted_date": "2020-02-11",
      "last_synced_at": "2026-10-03T10:50:24.168Z",
      "location_count": 3,
      "location_summary": "Secaucus, New Jersey • Charlotte, North Carolina • Raleigh, North Carolina",
      "locations": [
        {
          "city": "Secaucus",
          "state": "New Jersey"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Raleigh",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04143256"
    },
    {
      "nct_id": "NCT07010601",
      "title": "Tobacco Product Susceptibility and Substitutability by Rurality and Alcohol Use",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alcohol Use",
        "E-cigarette Use",
        "Cigarette Use"
      ],
      "interventions": [
        {
          "name": "Experimental Tobacco Marketplace",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Hypothetical Novel Nicotine Product Purchase Tasks",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Mark J Rzeszutek, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 737,
      "start_date": "2025-08-18",
      "completion_date": "2025-08-20",
      "has_results": false,
      "last_update_posted_date": "2025-09-23",
      "last_synced_at": "2026-10-03T10:50:24.168Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07010601"
    },
    {
      "nct_id": "NCT02185898",
      "title": "Evaluation of Environmental Emissions From Electronic Cigarettes and Tobacco-Burning Cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking"
      ],
      "interventions": [
        {
          "name": "Leading U.S. non-menthol cigarette",
          "type": "OTHER"
        },
        {
          "name": "Leading U.S. menthol cigarette",
          "type": "OTHER"
        },
        {
          "name": "Electronic cigarette #1",
          "type": "OTHER"
        },
        {
          "name": "Electronic cigarette #2",
          "type": "OTHER"
        },
        {
          "name": "Electronic cigarette #3",
          "type": "OTHER"
        },
        {
          "name": "U.S. Market-sample electronic cigarettes",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "R.J. Reynolds Vapor Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "21 Years to 99 Years"
      },
      "enrollment_count": 71,
      "start_date": "2014-05",
      "completion_date": "2015-02",
      "has_results": false,
      "last_update_posted_date": "2018-06-01",
      "last_synced_at": "2026-10-03T10:50:24.168Z",
      "location_count": 1,
      "location_summary": "Stockbridge, Georgia",
      "locations": [
        {
          "city": "Stockbridge",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02185898"
    },
    {
      "nct_id": "NCT02575885",
      "title": "Nicotine Delivery From Novel Non-Tobacco Electronic System in Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette Smoker",
        "Current Smoker",
        "Healthy Subject"
      ],
      "interventions": [
        {
          "name": "Electronic Cigarette",
          "type": "OTHER"
        },
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        },
        {
          "name": "Pharmacological Study",
          "type": "OTHER"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Roswell Park Cancer Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 36,
      "start_date": "2016-03-16",
      "completion_date": "2018-06-06",
      "has_results": false,
      "last_update_posted_date": "2018-06-12",
      "last_synced_at": "2026-10-03T10:50:24.168Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02575885"
    },
    {
      "nct_id": "NCT03492463",
      "title": "The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion Products",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Nicotine Dependence, Cigarettes"
      ],
      "interventions": [
        {
          "name": "Nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "Placebo patch",
          "type": "OTHER"
        },
        {
          "name": "E-cigarettes",
          "type": "OTHER"
        },
        {
          "name": "Non-nicotine e-cigarettes",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 94,
      "start_date": "2018-08-06",
      "completion_date": "2021-05-31",
      "has_results": true,
      "last_update_posted_date": "2023-02-08",
      "last_synced_at": "2026-10-03T10:50:24.168Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03492463"
    }
  ]
}