{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Non-Operative+Management&page=17", "query": { "intervention": "Non-Operative Management", "page": 17 }, "page_size": 10 }, "pagination": { "page": 17, "page_size": 10, "total_count": 443, "total_pages": 45, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Non-Operative+Management&page=18&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Non-Operative+Management&page=16&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-23T21:37:23.077Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03067181", "title": "Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Childhood Extracranial Germ Cell Tumor", "Extragonadal Embryonal Carcinoma", "Germ Cell Tumor", "Malignant Germ Cell Tumor", "Malignant Ovarian Teratoma", "Stage I Ovarian Choriocarcinoma", "Stage I Ovarian Embryonal Carcinoma AJCC v6 and v7", "Stage I Ovarian Yolk Sac Tumor AJCC v6 and v7", "Stage I Testicular Choriocarcinoma AJCC v6 and v7", "Stage I Testicular Embryonal Carcinoma AJCC v6 and v7", "Stage I Testicular Seminoma AJCC v6 and v7", "Stage I Testicular Yolk Sac Tumor AJCC v6 and v7", "Stage II Ovarian Choriocarcinoma", "Stage II Ovarian Embryonal Carcinoma AJCC v6 and v7", "Stage II Ovarian Yolk Sac Tumor AJCC v6 and v7", "Stage II Testicular Choriocarcinoma AJCC v6 and v7", "Stage II Testicular Embryonal Carcinoma AJCC v6 and v7", "Stage II Testicular Yolk Sac Tumor AJCC v6 and v7", "Stage III Ovarian Choriocarcinoma", "Stage III Ovarian Embryonal Carcinoma AJCC v6 and v7", "Stage III Ovarian Yolk Sac Tumor AJCC v6 and v7", "Stage III Testicular Choriocarcinoma AJCC v6 and v7", "Stage III Testicular Embryonal Carcinoma AJCC v6 and v7", "Stage III Testicular Yolk Sac Tumor AJCC v6 and v7", "Stage IV Ovarian Choriocarcinoma", "Stage IV Ovarian Embryonal Carcinoma AJCC v6 and v7", "Stage IV Ovarian Yolk Sac Tumor AJCC v6 and v7", "Testicular Mixed Choriocarcinoma and Embryonal Carcinoma", "Testicular Mixed Choriocarcinoma and Teratoma", "Testicular Mixed Choriocarcinoma and Yolk Sac Tumor" ], "interventions": [ { "name": "Best Practice", "type": "OTHER" }, { "name": "Biopsy Procedure", "type": "PROCEDURE" }, { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Bleomycin Sulfate", "type": "BIOLOGICAL" }, { "name": "Carboplatin", "type": "DRUG" }, { "name": "Cisplatin", "type": "DRUG" }, { "name": "Computed Tomography", "type": "PROCEDURE" }, { "name": "Etoposide", "type": "DRUG" }, { "name": "Magnetic Resonance Imaging", "type": "PROCEDURE" }, { "name": "Pulmonary Function Test", "type": "PROCEDURE" }, { "name": "Questionnaire Administration", "type": "OTHER" } ], "intervention_types": [ "OTHER", "PROCEDURE", "BIOLOGICAL", "DRUG" ], "sponsor": "Children's Oncology Group", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 1780, "start_date": "2017-05-25", "completion_date": "2027-06-30", "has_results": false, "last_update_posted_date": "2026-08-25", "last_synced_at": "2026-10-23T21:37:23.077Z", "location_count": 566, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Anchorage, Alaska + 338 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Anchorage", "state": "Alaska" }, { "city": "Anchorage", "state": "Alaska" }, { "city": "Anchorage", "state": "Alaska" } ], "official_url": "https://clinicaltrials.gov/study/NCT03067181" }, { "nct_id": "NCT01859091", "title": "Pilot Study on the Submental Area", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Body Fat Disorder" ], "interventions": [ { "name": "The Zeltiq System", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Zeltiq Aesthetics", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 14, "start_date": "2013-10", "completion_date": "2014-10", "has_results": true, "last_update_posted_date": "2025-08-15", "last_synced_at": "2026-10-23T21:37:23.077Z", "location_count": 1, "location_summary": "Pleasanton, California", "locations": [ { "city": "Pleasanton", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01859091" }, { "nct_id": "NCT05830058", "title": "Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Lung Non-Small Cell Carcinoma", "Malignant Solid Neoplasm", "Melanoma", "Renal Cell Carcinoma" ], "interventions": [ { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Computed Tomography", "type": "PROCEDURE" }, { "name": "Positron Emission Tomography", "type": "PROCEDURE" }, { "name": "Questionnaire Administration", "type": "OTHER" }, { "name": "Stereotactic Body Radiation Therapy", "type": "RADIATION" } ], "intervention_types": [ "PROCEDURE", "OTHER", "RADIATION" ], "sponsor": "City of Hope Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 32, "start_date": "2023-11-29", "completion_date": "2027-02-03", "has_results": false, "last_update_posted_date": "2026-08-31", "last_synced_at": "2026-10-23T21:37:23.077Z", "location_count": 2, "location_summary": "Duarte, California • Irvine, California", "locations": [ { "city": "Duarte", "state": "California" }, { "city": "Irvine", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05830058" }, { "nct_id": "NCT01534676", "title": "Effects of Transfusion of Older Stored Red Cells", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Sickle Cell Disease", "Thalassemia" ], "interventions": [ { "name": "Transfusion", "type": "PROCEDURE" }, { "name": "Blood", "type": "BIOLOGICAL" }, { "name": "Chelation therapy", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE", "BIOLOGICAL" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "1 Year", "maximum_age": "65 Years", "sex": "ALL", "summary": "1 Year to 65 Years" }, "enrollment_count": 3, "start_date": "2012-02", "completion_date": "2013-03", "has_results": true, "last_update_posted_date": "2016-10-05", "last_synced_at": "2026-10-23T21:37:23.077Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01534676" }, { "nct_id": "NCT00738335", "title": "Stereotactic Radiosurgery and Erlotinib in Treating Patients With Non-Small Cell Lung Cancer and Brain Metastases", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Lung Cancer", "Metastatic Cancer" ], "interventions": [ { "name": "erlotinib hydrochloride", "type": "DRUG" }, { "name": "immunoenzyme technique", "type": "OTHER" }, { "name": "laboratory biomarker analysis", "type": "OTHER" }, { "name": "liquid chromatography", "type": "OTHER" }, { "name": "mass spectrometry", "type": "OTHER" }, { "name": "pharmacological study", "type": "OTHER" }, { "name": "stereotactic radiosurgery", "type": "RADIATION" } ], "intervention_types": [ "DRUG", "OTHER", "RADIATION" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2009-01", "completion_date": "2009-07", "has_results": false, "last_update_posted_date": "2012-10-04", "last_synced_at": "2026-10-23T21:37:23.077Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00738335" }, { "nct_id": "NCT06910761", "title": "Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Anatomic Stage IV Breast Cancer AJCC v8", "Metastatic Breast Carcinoma", "Metastatic Lung Non-Small Cell Carcinoma", "Metastatic Malignant Neoplasm in the Leptomeninges", "Stage IV Lung Cancer AJCC v8" ], "interventions": [ { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Craniospinal Irradiation", "type": "RADIATION" }, { "name": "Electronic Health Record Review", "type": "OTHER" }, { "name": "Lumbar Puncture", "type": "PROCEDURE" }, { "name": "Magnetic Resonance Imaging", "type": "PROCEDURE" }, { "name": "Ommaya Reservoir Tap", "type": "PROCEDURE" }, { "name": "Questionnaire Administration", "type": "OTHER" }, { "name": "Volume Modulated Arc Therapy", "type": "RADIATION" } ], "intervention_types": [ "PROCEDURE", "RADIATION", "OTHER" ], "sponsor": "City of Hope Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 35, "start_date": "2025-05-05", "completion_date": "2028-10-02", "has_results": false, "last_update_posted_date": "2025-12-08", "last_synced_at": "2026-10-23T21:37:23.077Z", "location_count": 2, "location_summary": "Duarte, California • Irvine, California", "locations": [ { "city": "Duarte", "state": "California" }, { "city": "Irvine", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06910761" }, { "nct_id": "NCT06191094", "title": "Pre-operative Vabysmo in Patients With Non-clearing Vitreous Hemorrhage Secondary to Proliferative Diabetic Retinopathy", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Diabetic Retinopathy", "Vitreous Hemorrhage Due to Diabetes Mellitus" ], "interventions": [ { "name": "Faricimab Injection", "type": "DRUG" }, { "name": "sham treatment", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100, "start_date": "2024-07-12", "completion_date": "2028-01", "has_results": false, "last_update_posted_date": "2026-06-01", "last_synced_at": "2026-10-23T21:37:23.077Z", "location_count": 1, "location_summary": "Aurora, Colorado", "locations": [ { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT06191094" }, { "nct_id": "NCT05051722", "title": "Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Endometrial Cancer", "Cervical Cancer", "Atypical Endometrial Hyperplasia", "Cervical Dysplasia", "Adnexal Mass", "Ovarian Cancer" ], "interventions": [ { "name": "Vaginal Fluid Collection", "type": "DIAGNOSTIC_TEST" }, { "name": "Blood Collection", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 3110, "start_date": "2021-08-03", "completion_date": "2027-06-30", "has_results": false, "last_update_posted_date": "2026-09-29", "last_synced_at": "2026-10-23T21:37:23.077Z", "location_count": 25, "location_summary": "Phoenix, Arizona • Jacksonville, Florida • Miami, Florida + 21 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Orlando", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05051722" }, { "nct_id": "NCT01480167", "title": "The PRIORi-T Trial--Prospective Randomized Investigation of Radiofrequency Targeted Vertebral Augmentation", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Painful Osteoporotic Vertebral Compression Fractures (VCF)" ], "interventions": [ { "name": "Vertebral Augmentation (STABILIT)", "type": "DEVICE" }, { "name": "Non-operative Management", "type": "OTHER" } ], "intervention_types": [ "DEVICE", "OTHER" ], "sponsor": "DFINE Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "21 Years to 90 Years" }, "enrollment_count": 0, "start_date": "2011-11", "completion_date": null, "has_results": false, "last_update_posted_date": "2017-01-20", "last_synced_at": "2026-10-23T21:37:23.077Z", "location_count": 6, "location_summary": "St Louis, Missouri • Lebanon, New Hampshire • Mineola, New York + 3 more", "locations": [ { "city": "St Louis", "state": "Missouri" }, { "city": "Lebanon", "state": "New Hampshire" }, { "city": "Mineola", "state": "New York" }, { "city": "The Bronx", "state": "New York" }, { "city": "Hershey", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01480167" }, { "nct_id": "NCT04329494", "title": "PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Clinical Stage IV Gastric Cancer AJCC v8", "Clinical Stage IVA Gastric Cancer AJCC v8", "Clinical Stage IVB Gastric Cancer AJCC v8", "Malignant Uterine Neoplasm", "Metastatic Appendix Carcinoma", "Metastatic Colorectal Carcinoma", "Metastatic Gastric Carcinoma", "Metastatic Malignant Neoplasm in the Peritoneum", "Metastatic Malignant Solid Neoplasm", "Metastatic Ovarian Carcinoma", "Pathologic Stage IV Gastric Cancer AJCC v8", "Peritoneal Carcinomatosis", "Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8", "Stage IV Appendix Carcinoma AJCC v8", "Stage IV Colorectal Cancer AJCC v8", "Stage IV Ovarian Cancer AJCC v8", "Stage IV Uterine Corpus Cancer AJCC v8", "Stage IVA Appendix Carcinoma AJCC v8", "Stage IVA Colorectal Cancer AJCC v8", "Stage IVA Ovarian Cancer AJCC v8", "Stage IVA Uterine Corpus Cancer AJCC v8", "Stage IVB Appendix Carcinoma AJCC v8", "Stage IVB Colorectal Cancer AJCC v8", "Stage IVB Ovarian Cancer AJCC v8", "Stage IVB Uterine Corpus Cancer AJCC v8", "Stage IVC Appendix Carcinoma AJCC v8", "Stage IVC Colorectal Cancer AJCC v8" ], "interventions": [ { "name": "Biopsy", "type": "PROCEDURE" }, { "name": "Cisplatin", "type": "DRUG" }, { "name": "Doxorubicin", "type": "DRUG" }, { "name": "Fluorouracil", "type": "DRUG" }, { "name": "Intraperitoneal Chemotherapy", "type": "DEVICE" }, { "name": "Irinotecan", "type": "DRUG" }, { "name": "Leucovorin", "type": "DRUG" }, { "name": "Mitomycin", "type": "DRUG" }, { "name": "Oxaliplatin", "type": "DRUG" }, { "name": "Quality-of-Life Assessment", "type": "OTHER" }, { "name": "Questionnaire Administration", "type": "OTHER" } ], "intervention_types": [ "PROCEDURE", "DRUG", "DEVICE", "OTHER" ], "sponsor": "City of Hope Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 49, "start_date": "2020-08-21", "completion_date": "2028-01-05", "has_results": false, "last_update_posted_date": "2026-08-26", "last_synced_at": "2026-10-23T21:37:23.077Z", "location_count": 3, "location_summary": "Duarte, California • Jacksonville, Florida • Greenlawn, New York", "locations": [ { "city": "Duarte", "state": "California" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Greenlawn", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04329494" } ] }