{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Non-invasive+ventilation&page=2", "query": { "intervention": "Non-invasive ventilation", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Non-invasive+ventilation&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-27T10:17:20.199Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01680783", "title": "Non-Invasive Ventilation Via a Helmet Device for Patients Respiratory Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Acute Respiratory Distress Syndrome", "Shock", "Ventilatory Failure", "Cardiogenic Pulmonary Edema" ], "interventions": [ { "name": "Non invasive ventilation using a helmet hyperbaric device", "type": "DEVICE" }, { "name": "Noninvasive ventilation via facemask", "type": "OTHER" } ], "intervention_types": [ "DEVICE", "OTHER" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 83, "start_date": "2012-09", "completion_date": "2016-05", "has_results": true, "last_update_posted_date": "2020-07-14", "last_synced_at": "2026-09-27T10:17:20.199Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT01680783" }, { "nct_id": "NCT03349437", "title": "Vitabreath Pilot in Chronic Obstructive Pulmonary Disease (COPD) Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "COPD", "Dyspnea" ], "interventions": [ { "name": "Vitabreath Device", "type": "DEVICE" }, { "name": "Pursed Lip Breathing", "type": "OTHER" } ], "intervention_types": [ "DEVICE", "OTHER" ], "sponsor": "Philips Respironics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 25, "start_date": "2017-11-06", "completion_date": "2018-02-20", "has_results": true, "last_update_posted_date": "2019-05-08", "last_synced_at": "2026-09-27T10:17:20.199Z", "location_count": 2, "location_summary": "Youngstown, Ohio • Jefferson Hills, Pennsylvania", "locations": [ { "city": "Youngstown", "state": "Ohio" }, { "city": "Jefferson Hills", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT03349437" }, { "nct_id": "NCT04912544", "title": "Facilitating Patient Communication During Noninvasive Ventilation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Noninvasive Ventilation", "Speech Intelligibility" ], "interventions": [ { "name": "Noninvasive Ventilation Mask Microphone", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of Utah", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 10, "start_date": "2021-10-11", "completion_date": "2022-05-09", "has_results": false, "last_update_posted_date": "2022-08-01", "last_synced_at": "2026-09-27T10:17:20.199Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT04912544" }, { "nct_id": "NCT05918575", "title": "Postextubation Use of Noninvasive Respiratory Support in Severely Obese Patients", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Obesity, Morbid", "Extubation Failure" ], "interventions": [ { "name": "Noninvasive ventilation alternating with high flow nasal cannula", "type": "DEVICE" }, { "name": "High flow nasal cannula", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Rush University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 250, "start_date": "2023-07-10", "completion_date": "2028-12-01", "has_results": false, "last_update_posted_date": "2026-08-07", "last_synced_at": "2026-09-27T10:17:20.199Z", "location_count": 4, "location_summary": "Chicago, Illinois • Winfield, Illinois • Houston, Texas + 1 more", "locations": [ { "city": "Chicago", "state": "Illinois" }, { "city": "Winfield", "state": "Illinois" }, { "city": "Houston", "state": "Texas" }, { "city": "Milwaukee", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT05918575" }, { "nct_id": "NCT05440851", "title": "Platform of Randomized Adaptive Clinical Trials in Critical Illness", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Respiratory Insufficiency", "Extracorporeal Membrane Oxygenation Complication", "Mechanical Ventilation Pressure High" ], "interventions": [ { "name": "Ultra-Protective Ventilation Facilitated by Extracorporeal Support", "type": "OTHER" }, { "name": "Lung-Protective Ventilation (LPV)", "type": "OTHER" }, { "name": "Driving Pressure-Limited Ventilation (DPL)", "type": "OTHER" }, { "name": "Lung- and Diaphragm-Protective Ventilation and Sedation (LDPVS)", "type": "OTHER" }, { "name": "Early Cohort corticosteroid dose", "type": "DRUG" }, { "name": "Extended Cohort corticosteroid dose", "type": "DRUG" }, { "name": "Usual care without routine corticosteroids", "type": "DRUG" }, { "name": "Usual care without extending corticosteroids", "type": "DRUG" }, { "name": "Usual care with fludrocortisone", "type": "DRUG" }, { "name": "Usual care without fludrocortisone", "type": "DRUG" }, { "name": "Drug 4 mL:", "type": "DRUG" }, { "name": "Drug 40 mg:", "type": "DRUG" }, { "name": "PEEP-20", "type": "OTHER" }, { "name": "PEEP-AOP", "type": "OTHER" }, { "name": "PEEP-10", "type": "OTHER" }, { "name": "VV ECMO-facilitated strategy of earlier awakening, extubation and rehabilitation", "type": "OTHER" }, { "name": "Electrical impedance tomography (EIT)", "type": "OTHER" }, { "name": "no treatment / intervention arm is involved.", "type": "OTHER" }, { "name": "Usual care", "type": "OTHER" }, { "name": "Early Routine IMT", "type": "OTHER" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "University Health Network, Toronto", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 6250, "start_date": "2023-04-30", "completion_date": "2027-03-31", "has_results": false, "last_update_posted_date": "2026-05-07", "last_synced_at": "2026-09-27T10:17:20.199Z", "location_count": 26, "location_summary": "Tucson, Arizona • Los Angeles, California • San Diego, California + 19 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT05440851" }, { "nct_id": "NCT00686257", "title": "Evaluation Of The Total Face Mask For Emergency Application In Acute Respiratory Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Acute Respiratory Insufficiency" ], "interventions": [ { "name": "Total face mask (interface for NPPV)", "type": "DEVICE" }, { "name": "Comfort full or RT040 oronasal mask (interface for NPPV)", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Tufts Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2003-01", "completion_date": "2008-06", "has_results": true, "last_update_posted_date": "2018-06-25", "last_synced_at": "2026-09-27T10:17:20.199Z", "location_count": 2, "location_summary": "Boston, Massachusetts • Providence, Rhode Island", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Providence", "state": "Rhode Island" } ], "official_url": "https://clinicaltrials.gov/study/NCT00686257" }, { "nct_id": "NCT02930174", "title": "EIT Assessment of Lung Volume and Tidal Distribution: A Comparison of Non-Invasive Ventilation Devices", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Spontaneous Ventilation" ], "interventions": [ { "name": "noninvasive positive pressure ventilation", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of Michigan", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2018-02-01", "completion_date": "2018-03-27", "has_results": true, "last_update_posted_date": "2019-05-14", "last_synced_at": "2026-09-27T10:17:20.199Z", "location_count": 1, "location_summary": "Ann Arbor, Michigan", "locations": [ { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT02930174" }, { "nct_id": "NCT03529461", "title": "Use of Non-Invasive Positive Pressure Ventilation in Patients With Severe Obesity Undergoing Upper Endoscopy Procedures", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Severe Obesity", "Hypoxia" ], "interventions": [ { "name": "Non-invasive positive pressure ventilation through nasal mask", "type": "DEVICE" }, { "name": "Rescue non-invasive positive pressure ventilation through nasal mask", "type": "DEVICE" }, { "name": "Secondary rescue maneuvers", "type": "OTHER" } ], "intervention_types": [ "DEVICE", "OTHER" ], "sponsor": "Bristol Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 56, "start_date": "2017-04-25", "completion_date": "2018-04-18", "has_results": true, "last_update_posted_date": "2019-05-31", "last_synced_at": "2026-09-27T10:17:20.199Z", "location_count": 1, "location_summary": "Bristol, Connecticut", "locations": [ { "city": "Bristol", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT03529461" }, { "nct_id": "NCT03911856", "title": "Unmasking Right Ventricular and Pulmonary Derangements With Exercise and Oxygen in Early Stage Cardiopulmonary Diseases", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cardiopulmonary Disease" ], "interventions": [ { "name": "Echocardiography", "type": "OTHER" }, { "name": "Pulmonary Gas Exchange", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 7, "start_date": "2020-01-09", "completion_date": "2024-01-16", "has_results": false, "last_update_posted_date": "2024-03-12", "last_synced_at": "2026-09-27T10:17:20.199Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT03911856" }, { "nct_id": "NCT06833294", "title": "GentleFit Non-Invasive Ventilation (NIV) Interface Trial", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Device Ineffective", "Device Induced Injury" ], "interventions": [ { "name": "GentleFit Mask, GentleFit Prong, Standard of Care Interface", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Children's Hospital of Philadelphia", "sponsor_class": "OTHER", "healthy_volunteers": null, "eligibility": { "minimum_age": "38 Weeks", "maximum_age": "3 Years", "sex": "ALL", "summary": "38 Weeks to 3 Years" }, "enrollment_count": 4, "start_date": "2025-10-24", "completion_date": "2026-01-20", "has_results": false, "last_update_posted_date": "2026-02-09", "last_synced_at": "2026-09-27T10:17:20.199Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT06833294" } ] }