{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Non-nicotine+e-cigarettes&page=2",
    "query": {
      "intervention": "Non-nicotine e-cigarettes",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Non-nicotine+e-cigarettes&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-29T04:20:08.036Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06442384",
      "title": "Remote Trial - Tobacco Product Standard (VLNC)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "Tobacco and non-tobacco e-cigarettes",
          "type": "OTHER"
        },
        {
          "name": "Tobacco only e-cigarettes",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Masonic Cancer Center, University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 11,
      "start_date": "2024-09-11",
      "completion_date": "2025-04-07",
      "has_results": false,
      "last_update_posted_date": "2025-04-10",
      "last_synced_at": "2026-09-29T04:20:08.036Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06442384"
    },
    {
      "nct_id": "NCT02102100",
      "title": "The Effects of Menthol as Delivered by an Electronic Cigarette on the Desirability of Nicotine in Tobacco Users",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "nicotine",
          "type": "DRUG"
        },
        {
          "name": "menthol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 57,
      "start_date": "2014-03-26",
      "completion_date": "2016-07-11",
      "has_results": true,
      "last_update_posted_date": "2020-03-19",
      "last_synced_at": "2026-09-29T04:20:08.036Z",
      "location_count": 2,
      "location_summary": "West Haven, Connecticut",
      "locations": [
        {
          "city": "West Haven",
          "state": "Connecticut"
        },
        {
          "city": "West Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02102100"
    },
    {
      "nct_id": "NCT02433015",
      "title": "Neurophysiological and Immunological Effects of the Transition From Combustible to Electronic Cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Smoking",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Electronic Cigarette",
          "type": "OTHER"
        },
        {
          "name": "Tobacco Cigarette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Laureate Institute for Brain Research, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 27,
      "start_date": "2015-01",
      "completion_date": "2016-09-24",
      "has_results": false,
      "last_update_posted_date": "2017-06-28",
      "last_synced_at": "2026-09-29T04:20:08.036Z",
      "location_count": 1,
      "location_summary": "Tulsa, Oklahoma",
      "locations": [
        {
          "city": "Tulsa",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02433015"
    },
    {
      "nct_id": "NCT07132814",
      "title": "Abuse Liability for Five Modern Oral Nicotine Products",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "Smoking Behaviors",
        "Tobacco Use",
        "Tobacco Smoking"
      ],
      "interventions": [
        {
          "name": "Product A",
          "type": "OTHER"
        },
        {
          "name": "Product B",
          "type": "OTHER"
        },
        {
          "name": "Product C",
          "type": "OTHER"
        },
        {
          "name": "Product D",
          "type": "OTHER"
        },
        {
          "name": "Product E",
          "type": "OTHER"
        },
        {
          "name": "Product F",
          "type": "OTHER"
        },
        {
          "name": "Product N",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "RAI Services Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 40,
      "start_date": "2025-12-15",
      "completion_date": "2026-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-30",
      "last_synced_at": "2026-09-29T04:20:08.036Z",
      "location_count": 1,
      "location_summary": "Overland Park, Kansas",
      "locations": [
        {
          "city": "Overland Park",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07132814"
    },
    {
      "nct_id": "NCT07460622",
      "title": "A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "E-cigarette Use/Vaping Prevention",
        "Nicotine Dependence Prevention",
        "Adolescent Mental Health"
      ],
      "interventions": [
        {
          "name": "Virtual Reality E-Cigarette Prevention Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "15 Years",
        "sex": "ALL",
        "summary": "11 Years to 15 Years"
      },
      "enrollment_count": 1251,
      "start_date": "2026-10-01",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2026-03-10",
      "last_synced_at": "2026-09-29T04:20:08.036Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07460622"
    },
    {
      "nct_id": "NCT05958992",
      "title": "Effects of e-Cigarettes on Perceptions and Behavior - Remote Substudy # 2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarette Use",
        "Cigarette Smoking",
        "Cigarette Use, Electronic",
        "Vaping"
      ],
      "interventions": [
        {
          "name": "E-cigarette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 461,
      "start_date": "2020-08-25",
      "completion_date": "2022-05-01",
      "has_results": false,
      "last_update_posted_date": "2023-07-25",
      "last_synced_at": "2026-09-29T04:20:08.036Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05958992"
    },
    {
      "nct_id": "NCT02188511",
      "title": "Effects of Electronic Cigarettes on Lung Biology",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lung Disease",
        "Lung Disorder"
      ],
      "interventions": [
        {
          "name": "Group A",
          "type": "OTHER"
        },
        {
          "name": "Group B",
          "type": "OTHER"
        },
        {
          "name": "Group C",
          "type": "OTHER"
        },
        {
          "name": "Group D",
          "type": "OTHER"
        },
        {
          "name": "Group E",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "21 Years to 85 Years"
      },
      "enrollment_count": 13,
      "start_date": "2014-01",
      "completion_date": "2018-07",
      "has_results": false,
      "last_update_posted_date": "2020-07-24",
      "last_synced_at": "2026-09-29T04:20:08.036Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02188511"
    },
    {
      "nct_id": "NCT04238832",
      "title": "Salt-Based E-cigarette",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "Salt Base Nicotine",
          "type": "OTHER"
        },
        {
          "name": "Free Base Nicotine",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2020-06-16",
      "completion_date": "2021-07-23",
      "has_results": false,
      "last_update_posted_date": "2021-08-09",
      "last_synced_at": "2026-09-29T04:20:08.036Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04238832"
    },
    {
      "nct_id": "NCT06534905",
      "title": "E-cigarette Switching Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use",
        "Opioid Use Disorder",
        "Tobacco-Related Disorders"
      ],
      "interventions": [
        {
          "name": "E-cigarette",
          "type": "OTHER"
        },
        {
          "name": "Control/Standard Advice",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2024-11-25",
      "completion_date": "2025-10-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-10",
      "last_synced_at": "2026-09-29T04:20:08.036Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06534905"
    },
    {
      "nct_id": "NCT05918887",
      "title": "Feasibility and Acceptability of Switching to E-cigarettes Among Cigarette Smokers Engaged in SUD Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Dependence Caused by Cigarettes"
      ],
      "interventions": [
        {
          "name": "NJOY ACE commercial e-cigarette",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Nevada, Reno",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 31,
      "start_date": "2024-06-18",
      "completion_date": "2024-09-13",
      "has_results": false,
      "last_update_posted_date": "2025-05-13",
      "last_synced_at": "2026-09-29T04:20:08.036Z",
      "location_count": 1,
      "location_summary": "Reno, Nevada",
      "locations": [
        {
          "city": "Reno",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05918887"
    }
  ]
}