{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=None+%28Historical%29",
    "query": {
      "intervention": "None (Historical)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 24,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=None+%28Historical%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-20T15:13:48.717Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04241796",
      "title": "Assessment of the Implementation of an Investigational Multi-Cancer Early Detection Test Into Clinical Practice",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cancer"
      ],
      "interventions": [
        {
          "name": "Multi-Cancer Early Detection Test",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "GRAIL, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 6662,
      "start_date": "2019-12-12",
      "completion_date": "2022-01-05",
      "has_results": false,
      "last_update_posted_date": "2022-10-25",
      "last_synced_at": "2026-09-20T15:13:48.717Z",
      "location_count": 11,
      "location_summary": "Roseville, California • Pensacola, Florida • Boston, Massachusetts + 8 more",
      "locations": [
        {
          "city": "Roseville",
          "state": "California"
        },
        {
          "city": "Pensacola",
          "state": "Florida"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04241796"
    },
    {
      "nct_id": "NCT01651806",
      "title": "Weighted Versus Uniform Dose of Tranexamic Acid in Patients Undergoing Primary, Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Osteoarthritis",
        "Intraoperative Bleeding"
      ],
      "interventions": [
        {
          "name": "Tranexamic Acid standard dose",
          "type": "DRUG"
        },
        {
          "name": "Females Tranexamic Acid weighted dose",
          "type": "DRUG"
        },
        {
          "name": "Females receiving a uniform dose of TA",
          "type": "DRUG"
        },
        {
          "name": "Males Weighted Dose TA",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 65,
      "start_date": "2012-05",
      "completion_date": "2015-03",
      "has_results": true,
      "last_update_posted_date": "2017-12-13",
      "last_synced_at": "2026-09-20T15:13:48.717Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01651806"
    },
    {
      "nct_id": "NCT06340152",
      "title": "Multi-Omics for Maternal Health After Preeclampsia",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pre-Eclampsia",
        "Pregnancy Induced Hypertension"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 1100,
      "start_date": "2023-12-20",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2025-04-06",
      "last_synced_at": "2026-09-20T15:13:48.717Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06340152"
    },
    {
      "nct_id": "NCT00843375",
      "title": "Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Colonic Neoplasms"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Michigan Rogel Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1200,
      "start_date": "2019-08-07",
      "completion_date": "2028-03",
      "has_results": false,
      "last_update_posted_date": "2026-05-11",
      "last_synced_at": "2026-09-20T15:13:48.717Z",
      "location_count": 11,
      "location_summary": "Los Angeles, California • Urbana, Illinois • Boston, Massachusetts + 8 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Urbana",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00843375"
    },
    {
      "nct_id": "NCT00742911",
      "title": "Phase I Study of Disulfiram and Copper Gluconate for the Treatment of Refractory Solid Tumors Involving the Liver",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Cancer"
      ],
      "interventions": [
        {
          "name": "Disulfiram",
          "type": "DRUG"
        },
        {
          "name": "Copper Gluconate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2008-07",
      "completion_date": "2013-03",
      "has_results": false,
      "last_update_posted_date": "2014-10-31",
      "last_synced_at": "2026-09-20T15:13:48.717Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00742911"
    },
    {
      "nct_id": "NCT06147830",
      "title": "A Study to Describe the Characteristics, Health Care Interventions and Outcomes of Patients With Major Bleedings in the Presence of Factor Xa Inhibitor Treatment",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Major Bleeding"
      ],
      "interventions": [
        {
          "name": "None (Observational study)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "AstraZeneca",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "130 Years",
        "sex": "ALL",
        "summary": "18 Years to 130 Years"
      },
      "enrollment_count": 2202,
      "start_date": "2023-12-04",
      "completion_date": "2024-11-30",
      "has_results": false,
      "last_update_posted_date": "2025-11-03",
      "last_synced_at": "2026-09-20T15:13:48.717Z",
      "location_count": 25,
      "location_summary": "Chandler, Arizona • Orange, California • Sacramento, California + 22 more",
      "locations": [
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Lakewood",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06147830"
    },
    {
      "nct_id": "NCT02745158",
      "title": "The Fibrodysplasia Ossificans Progressiva (FOP) Registry",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fibrodysplasia Ossificans Progressiva (FOP)"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "The International FOP Association",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 800,
      "start_date": "2015-07",
      "completion_date": "2040-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-08",
      "last_synced_at": "2026-09-20T15:13:48.717Z",
      "location_count": 1,
      "location_summary": "North Kansas City, Missouri",
      "locations": [
        {
          "city": "North Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02745158"
    },
    {
      "nct_id": "NCT04923386",
      "title": "mRNA Based-Covid-19 Vaccine Effects on Blood Glucose Levels",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetes Mellitus, Type 2",
        "Diabetes Mellitus, Type 1",
        "Hyperglycemia",
        "Vaccine Adverse Reaction"
      ],
      "interventions": [
        {
          "name": "None (not interventional)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Levenson, David I., M.D.",
      "sponsor_class": "INDIV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2021-06-15",
      "completion_date": "2022-02-01",
      "has_results": false,
      "last_update_posted_date": "2022-08-17",
      "last_synced_at": "2026-09-20T15:13:48.717Z",
      "location_count": 1,
      "location_summary": "Boca Raton, Florida",
      "locations": [
        {
          "city": "Boca Raton",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04923386"
    },
    {
      "nct_id": "NCT06574672",
      "title": "Embedded Palliative Care in the MICU",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critical Illness",
        "End of Life",
        "Quality of Life"
      ],
      "interventions": [
        {
          "name": "Embedded Hospice and Palliative Care Practitioner",
          "type": "OTHER"
        },
        {
          "name": "Embedded Hospice and Palliative Care Practitioner (Group Effect)",
          "type": "OTHER"
        },
        {
          "name": "None (Historical)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2600,
      "start_date": "2024-07-29",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2025-07-16",
      "last_synced_at": "2026-09-20T15:13:48.717Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06574672"
    },
    {
      "nct_id": "NCT05419245",
      "title": "Survey Study and Records Review of Treatment Outcomes in Freeman-Sheldon Syndrome",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Freeman-Burian Syndrome",
        "Freeman-Sheldon Syndrome",
        "Whistling Face Syndrome",
        "Sheldon-Hall Syndrome",
        "Freeman-Sheldon Syndrome Variant",
        "Arthrogryposis Distal Type 1",
        "Arthrogryposis Distal Type 3",
        "Gordon Syndrome"
      ],
      "interventions": [
        {
          "name": "Guided Health History for Freeman-Burian Syndrome Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Freeman-Burian syndrome Semi-Structured Quality of Life Interview",
          "type": "OTHER"
        },
        {
          "name": "Medical Records Review",
          "type": "OTHER"
        },
        {
          "name": "PTSD Checklist for DSM-5",
          "type": "OTHER"
        },
        {
          "name": "Modified Flanagan Quality of Life Scale",
          "type": "OTHER"
        },
        {
          "name": "Center for Epidemiologic Studies Depression Scale",
          "type": "OTHER"
        },
        {
          "name": "Review of Systems",
          "type": "OTHER"
        },
        {
          "name": "FACE-Q | Craniofacial - Appearance of the Face",
          "type": "OTHER"
        },
        {
          "name": "FACE-Q | Craniofacial - Appearance Distress",
          "type": "OTHER"
        },
        {
          "name": "FACE-Q | Craniofacial - Facial Function",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Dufresne, Craig, MD, PC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 20,
      "start_date": "2022-06-01",
      "completion_date": "2023-12",
      "has_results": false,
      "last_update_posted_date": "2022-07-19",
      "last_synced_at": "2026-09-20T15:13:48.717Z",
      "location_count": 1,
      "location_summary": "Fairfax, Virginia",
      "locations": [
        {
          "city": "Fairfax",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05419245"
    }
  ]
}