{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Noninvasive+Ventilation&page=2",
    "query": {
      "intervention": "Noninvasive Ventilation",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Noninvasive+Ventilation&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-26T09:03:29.829Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03522805",
      "title": "Impact of Non-invasive Ventilation in Hypercapnic COPD",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Copd",
        "Chronic Obstructive Pulmonary Disease",
        "Hypercapnia",
        "Chronic Respiratory Failure",
        "Hypoventilation"
      ],
      "interventions": [
        {
          "name": "High-intensity non-invasive ventilation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "45 Years to 75 Years"
      },
      "enrollment_count": 6,
      "start_date": "2018-04-23",
      "completion_date": "2018-11-21",
      "has_results": false,
      "last_update_posted_date": "2020-08-27",
      "last_synced_at": "2026-09-26T09:03:29.829Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03522805"
    },
    {
      "nct_id": "NCT02236559",
      "title": "High Flow Therapy for the Treatment of Respiratory Failure in the ED",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "Noninvasive positive pressure ventilation (NIPPV)",
          "type": "DEVICE"
        },
        {
          "name": "Vapotherm",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vapotherm, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 204,
      "start_date": "2014-09",
      "completion_date": "2017-02",
      "has_results": true,
      "last_update_posted_date": "2019-05-23",
      "last_synced_at": "2026-09-26T09:03:29.829Z",
      "location_count": 5,
      "location_summary": "Athens, Georgia • Florence, South Carolina • Chattanooga, Tennessee + 2 more",
      "locations": [
        {
          "city": "Athens",
          "state": "Georgia"
        },
        {
          "city": "Florence",
          "state": "South Carolina"
        },
        {
          "city": "Chattanooga",
          "state": "Tennessee"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "The Woodlands",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02236559"
    },
    {
      "nct_id": "NCT03734822",
      "title": "Comparative Analysis of CO2 Monitoring Methods in Patients With CF Undergoing General Anesthesia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cystic Fibrosis"
      ],
      "interventions": [
        {
          "name": "End tidal CO2 (EtCO2)",
          "type": "OTHER"
        },
        {
          "name": "Transcutaneous CO2 (TCO2)",
          "type": "DEVICE"
        },
        {
          "name": "Capillary CO2 (CapCO2)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Arterial blood gas (ABG)",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Nationwide Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 47,
      "start_date": "2016-03-10",
      "completion_date": "2017-12-20",
      "has_results": true,
      "last_update_posted_date": "2019-03-14",
      "last_synced_at": "2026-09-26T09:03:29.829Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03734822"
    },
    {
      "nct_id": "NCT06053684",
      "title": "Non-Invasive Ventilation Versus Neurally-Adjusted Ventilatory Assistance (NAVA) for the Treatment of Bronchiolitis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bronchiolitis"
      ],
      "interventions": [
        {
          "name": "Standard Non-Invasive Mechanical Servo Ventilation",
          "type": "DEVICE"
        },
        {
          "name": "Neurally-Adjusted Ventilatory Assistance (NAVA) Non-Invasive Mechanical Servo Ventilation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "2 Years",
        "sex": "ALL",
        "summary": "0 Years to 2 Years"
      },
      "enrollment_count": 130,
      "start_date": "2023-12-18",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2025-09-05",
      "last_synced_at": "2026-09-26T09:03:29.829Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06053684"
    },
    {
      "nct_id": "NCT05961683",
      "title": "Evaluating Pressures During Non-invasive Ventilation Utilizing NIV Plus Software",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress Syndrome, Newborn",
        "Apnea of Newborn"
      ],
      "interventions": [
        {
          "name": "NIV plus software",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Keck School of Medicine of USC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Days",
        "maximum_age": "30 Days",
        "sex": "ALL",
        "summary": "0 Days to 30 Days"
      },
      "enrollment_count": 100,
      "start_date": "2023-08-01",
      "completion_date": "2024-09-30",
      "has_results": false,
      "last_update_posted_date": "2023-07-27",
      "last_synced_at": "2026-09-26T09:03:29.829Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05961683"
    },
    {
      "nct_id": "NCT04052542",
      "title": "METEOR Think NIV Pilot",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "Traditional online continuing education",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Interprofessional education",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Just-in-time education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1328,
      "start_date": "2019-08-28",
      "completion_date": "2019-11-20",
      "has_results": true,
      "last_update_posted_date": "2021-10-06",
      "last_synced_at": "2026-09-26T09:03:29.829Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04052542"
    },
    {
      "nct_id": "NCT01882257",
      "title": "Home-Based Diagnosis and Management of Sleep-Related Breathing Disorders in Spinal Cord Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obstructive Sleep Apnea",
        "Hypercapnia",
        "Spinal Cord Injury"
      ],
      "interventions": [
        {
          "name": "BiPAP",
          "type": "DEVICE"
        },
        {
          "name": "BiPAP/AVAPS (Phillips Respironics)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 93,
      "start_date": "2011-10",
      "completion_date": "2016-02",
      "has_results": true,
      "last_update_posted_date": "2017-01-11",
      "last_synced_at": "2026-09-26T09:03:29.829Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01882257"
    },
    {
      "nct_id": "NCT03934619",
      "title": "Dolores One: Maximizing Functional Communication for Adults",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Communication"
      ],
      "interventions": [
        {
          "name": "Dolores One",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 0,
      "start_date": "2019-10-07",
      "completion_date": "2020-03-31",
      "has_results": false,
      "last_update_posted_date": "2022-04-15",
      "last_synced_at": "2026-09-26T09:03:29.829Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03934619"
    },
    {
      "nct_id": "NCT01368614",
      "title": "AVAPS-AE Efficacy Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity Hypoventilation Syndrome"
      ],
      "interventions": [
        {
          "name": "AVAPS-AE Mode of Therapy",
          "type": "DEVICE"
        },
        {
          "name": "Respironics OnmiLab BiPAP S mode",
          "type": "DEVICE"
        },
        {
          "name": "Respironics OmniLab Advanced CPAP mode",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Philips Respironics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 90,
      "start_date": "2011-09-12",
      "completion_date": "2013-05-30",
      "has_results": true,
      "last_update_posted_date": "2019-04-26",
      "last_synced_at": "2026-09-26T09:03:29.829Z",
      "location_count": 2,
      "location_summary": "Tucson, Arizona • Chicago, Illinois",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01368614"
    },
    {
      "nct_id": "NCT04709562",
      "title": "Clinical Stabilization of Hypercapnia: NIPPV v HVNI",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypercapnic Respiratory Failure",
        "Chronic Obstructive Pulmonary Disease",
        "Dyspnea",
        "Hypercapnic Acidosis"
      ],
      "interventions": [
        {
          "name": "High Velocity Nasal Insufflation (HVNI)",
          "type": "DEVICE"
        },
        {
          "name": "Noninvasive Positive Pressure Ventilation (NIPPV)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vapotherm, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 68,
      "start_date": "2020-11-11",
      "completion_date": "2023-06-22",
      "has_results": true,
      "last_update_posted_date": "2024-08-09",
      "last_synced_at": "2026-09-26T09:03:29.829Z",
      "location_count": 7,
      "location_summary": "Los Angeles, California • Oxnard, California • Washington D.C., District of Columbia + 4 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Oxnard",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Camden",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04709562"
    }
  ]
}