{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Noninvasive+positive+pressure+ventilation",
    "query": {
      "intervention": "Noninvasive positive pressure ventilation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 43,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Noninvasive+positive+pressure+ventilation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-24T07:48:30.250Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03085329",
      "title": "A Study to Evaluate the Efficacy of Seattle-PAP for the Respiratory Support of Premature Infants",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premature Birth"
      ],
      "interventions": [
        {
          "name": "Seattle-PAP",
          "type": "DEVICE"
        },
        {
          "name": "Conventional bubble nasal CPAP",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Seattle Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "30 Weeks",
        "sex": "ALL",
        "summary": "Up to 30 Weeks"
      },
      "enrollment_count": 220,
      "start_date": "2017-02-10",
      "completion_date": "2019-02-09",
      "has_results": false,
      "last_update_posted_date": "2017-03-22",
      "last_synced_at": "2026-09-24T07:48:30.250Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03085329"
    },
    {
      "nct_id": "NCT01882257",
      "title": "Home-Based Diagnosis and Management of Sleep-Related Breathing Disorders in Spinal Cord Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obstructive Sleep Apnea",
        "Hypercapnia",
        "Spinal Cord Injury"
      ],
      "interventions": [
        {
          "name": "BiPAP",
          "type": "DEVICE"
        },
        {
          "name": "BiPAP/AVAPS (Phillips Respironics)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 93,
      "start_date": "2011-10",
      "completion_date": "2016-02",
      "has_results": true,
      "last_update_posted_date": "2017-01-11",
      "last_synced_at": "2026-09-24T07:48:30.250Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01882257"
    },
    {
      "nct_id": "NCT02523352",
      "title": "Effects of PEEP on Heart and Lungs in Obese Subjects",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Pulmonary Atelectasis",
        "Obesity Hypoventilation Syndrome",
        "Magnetic Resonance Imaging",
        "Respiratory Mechanics",
        "Electrical Impedance Tomography",
        "Trans-Thoracic Echocardiography"
      ],
      "interventions": [
        {
          "name": "Non-Invasive Ventilation",
          "type": "PROCEDURE"
        },
        {
          "name": "Esophageal catheter positioning",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 35,
      "start_date": "2018-04-05",
      "completion_date": "2022-12-31",
      "has_results": false,
      "last_update_posted_date": "2020-11-17",
      "last_synced_at": "2026-09-24T07:48:30.250Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02523352"
    },
    {
      "nct_id": "NCT03407287",
      "title": "Peripheral Venous Analysis (PIVA) for Predicting Volume Responsiveness and Fluid Status",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Systemic Inflammatory Response Syndrome",
        "Distributive Shock",
        "Hypotension and Shock",
        "Decompensated Congestive Heart Failure",
        "Atrial Fibrillation",
        "High Risk Non-cardiac Surgery"
      ],
      "interventions": [
        {
          "name": "Peripheral Intravenous Analysis (PIVA)",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard of care invasive vascular monitoring",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard noninvasive vascular monitoring",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 180,
      "start_date": "2018-01-08",
      "completion_date": "2020-12-01",
      "has_results": false,
      "last_update_posted_date": "2021-04-12",
      "last_synced_at": "2026-09-24T07:48:30.250Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03407287"
    },
    {
      "nct_id": "NCT01188473",
      "title": "Early Noninvasive Positive Pressure Ventilation in Children With Status Asthmaticus",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Status Asthmaticus"
      ],
      "interventions": [
        {
          "name": "NPPV plus standard of care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Southern Illinois University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "1 Year to 18 Years"
      },
      "enrollment_count": 0,
      "start_date": "2009-01",
      "completion_date": "2010-01",
      "has_results": false,
      "last_update_posted_date": "2014-12-19",
      "last_synced_at": "2026-09-24T07:48:30.250Z",
      "location_count": 1,
      "location_summary": "Springfield, Illinois",
      "locations": [
        {
          "city": "Springfield",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01188473"
    },
    {
      "nct_id": "NCT03137225",
      "title": "Noninvasive NAVA Versus NIPPV in Low Birthweight Premature Infants",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Noninvasive Ventilation",
        "Low Birth Weight"
      ],
      "interventions": [
        {
          "name": "Neurally Adjusted Ventilatory Assist",
          "type": "DEVICE"
        },
        {
          "name": "Nasal Intermittent Positive Pressure Ventilation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1,
      "start_date": "2017-04-15",
      "completion_date": "2019-06-30",
      "has_results": true,
      "last_update_posted_date": "2019-11-12",
      "last_synced_at": "2026-09-24T07:48:30.250Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03137225"
    },
    {
      "nct_id": "NCT06609135",
      "title": "Relationship Between EIT and Respiratory Status in Very Preterm Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Lung Disease of Prematurity",
        "Bronchopulmonary Dysplasia",
        "Premature Lungs"
      ],
      "interventions": [
        {
          "name": "Sentec LuMon Device (EIT system)",
          "type": "DEVICE"
        },
        {
          "name": "Sentec Digital Monitoring System (transcutaneous CO2 monitor)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Lawrence Rhein",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Days",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "5 Days and older"
      },
      "enrollment_count": 20,
      "start_date": "2023-11-04",
      "completion_date": "2024-08-31",
      "has_results": true,
      "last_update_posted_date": "2025-10-09",
      "last_synced_at": "2026-09-24T07:48:30.250Z",
      "location_count": 1,
      "location_summary": "Worcester, Massachusetts",
      "locations": [
        {
          "city": "Worcester",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06609135"
    },
    {
      "nct_id": "NCT02114944",
      "title": "Treatment of Dyspnea in Do-not-intubate Patients",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Respiratory Failure",
        "Acute on Chronic Respiratory Failure",
        "Dyspnea"
      ],
      "interventions": [
        {
          "name": "NIV",
          "type": "DEVICE"
        },
        {
          "name": "CPAP",
          "type": "DEVICE"
        },
        {
          "name": "Standard oxygen",
          "type": "DEVICE"
        },
        {
          "name": "HFNC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Tufts Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2014-04",
      "completion_date": "2023-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-05-13",
      "last_synced_at": "2026-09-24T07:48:30.250Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02114944"
    },
    {
      "nct_id": "NCT02514798",
      "title": "Pilot Study of Physiological Effect of High-Flow Nasal Cannula on Respiratory Pattern and Work of Breathing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "COPD"
      ],
      "interventions": [
        {
          "name": "Esophageal and gastric balloons",
          "type": "OTHER"
        },
        {
          "name": "Respiratory Inductance Plethysmography (RIP) system",
          "type": "OTHER"
        },
        {
          "name": "Sentec transcutaneous monitoring system",
          "type": "OTHER"
        },
        {
          "name": "High-flow humidified nasal oxygen delivery system",
          "type": "DEVICE"
        },
        {
          "name": "CPAP (Positive Control)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Tufts Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 11,
      "start_date": "2015-07",
      "completion_date": "2018-04-01",
      "has_results": false,
      "last_update_posted_date": "2022-05-10",
      "last_synced_at": "2026-09-24T07:48:30.250Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02514798"
    },
    {
      "nct_id": "NCT01939067",
      "title": "Infant Pulmonary Mechanics: High Flow Nasal Cannula Versus Nasal CPAP",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Respiratory Distress",
        "Lung Injury"
      ],
      "interventions": [
        {
          "name": "Heated Humidified High Flow Nasal Cannula",
          "type": "DEVICE"
        },
        {
          "name": "Nasal Continuous Positive Airway Pressure",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Hours",
        "maximum_age": "72 Hours",
        "sex": "ALL",
        "summary": "2 Hours to 72 Hours"
      },
      "enrollment_count": 0,
      "start_date": "2014-03",
      "completion_date": "2014-03",
      "has_results": false,
      "last_update_posted_date": "2015-09-15",
      "last_synced_at": "2026-09-24T07:48:30.250Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01939067"
    }
  ]
}