{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Norco+%28Hydrocodone+and+Acetaminophen%29",
    "query": {
      "intervention": "Norco (Hydrocodone and Acetaminophen)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 84,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Norco+%28Hydrocodone+and+Acetaminophen%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-02T08:11:59.149Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00404391",
      "title": "A Study Comparing the Analgesic Activity of Extended Release Hydrocodone/Acetaminophen (Vicodin® CR) and Placebo in Subjects With Pain Following Bunionectomy Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Hydrocodone/Acetaminophen Extended Release",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Abbott",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 210,
      "start_date": "2003-10",
      "completion_date": "2004-03",
      "has_results": false,
      "last_update_posted_date": "2011-01-19",
      "last_synced_at": "2026-10-02T08:11:59.149Z",
      "location_count": 4,
      "location_summary": "Owing Mills, Maryland • Austin, Texas • San Marcos, Texas + 1 more",
      "locations": [
        {
          "city": "Owing Mills",
          "state": "Maryland"
        },
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "San Marcos",
          "state": "Texas"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00404391"
    },
    {
      "nct_id": "NCT03020875",
      "title": "IV vs Oral Acetaminophen in Spine Fusion Perioperative Care",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Multimodal Analgesic Approach"
      ],
      "interventions": [
        {
          "name": "Ofirmev",
          "type": "DRUG"
        },
        {
          "name": "Per Os Acetaminophen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 166,
      "start_date": "2017-01",
      "completion_date": "2025-02-03",
      "has_results": false,
      "last_update_posted_date": "2026-04-28",
      "last_synced_at": "2026-10-02T08:11:59.149Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03020875"
    },
    {
      "nct_id": "NCT04939987",
      "title": "Opioid-Free Pain Control Regiment Following Robotic Radical Prostatectomy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Radical Prostatectomies"
      ],
      "interventions": [
        {
          "name": "Tramadol",
          "type": "DRUG"
        },
        {
          "name": "Gabapentin",
          "type": "DRUG"
        },
        {
          "name": "Hydrocodone-Acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "Oxycodone-Acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "Ketorolac",
          "type": "DRUG"
        },
        {
          "name": "Acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "Ketorolac tromethamine",
          "type": "DRUG"
        },
        {
          "name": "Ketamine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "75 Years",
        "sex": "MALE",
        "summary": "40 Years to 75 Years · Male only"
      },
      "enrollment_count": 0,
      "start_date": "2022-08",
      "completion_date": "2022-10",
      "has_results": false,
      "last_update_posted_date": "2022-09-06",
      "last_synced_at": "2026-10-02T08:11:59.149Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04939987"
    },
    {
      "nct_id": "NCT02588027",
      "title": "Effect of Ibuprofen on Postoperative Opiate Medication Use and Shoulder Functional Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rotator Cuff Tear Arthropathy"
      ],
      "interventions": [
        {
          "name": "Ibuprofen",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2015-10",
      "completion_date": "2022-09",
      "has_results": true,
      "last_update_posted_date": "2024-12-06",
      "last_synced_at": "2026-10-02T08:11:59.149Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02588027"
    },
    {
      "nct_id": "NCT02991222",
      "title": "Bioavailability Study of SPARC001(Study 1) in Healthy Adult Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "SPARC001 type I",
          "type": "DRUG"
        },
        {
          "name": "SPARC001 type II",
          "type": "DRUG"
        },
        {
          "name": "Reference001 type I",
          "type": "DRUG"
        },
        {
          "name": "Reference001 type II",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sun Pharma Advanced Research Company Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 24,
      "start_date": "2017-01-15",
      "completion_date": "2017-04",
      "has_results": false,
      "last_update_posted_date": "2019-05-03",
      "last_synced_at": "2026-10-02T08:11:59.149Z",
      "location_count": 1,
      "location_summary": "Secaucus, New Jersey",
      "locations": [
        {
          "city": "Secaucus",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02991222"
    },
    {
      "nct_id": "NCT03818919",
      "title": "Nonopioid Analgesia After Rotator Cuff Repair",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Rotator Cuff Tear"
      ],
      "interventions": [
        {
          "name": "Celecoxib",
          "type": "DRUG"
        },
        {
          "name": "Ketorolac",
          "type": "DRUG"
        },
        {
          "name": "Gabapentin",
          "type": "DRUG"
        },
        {
          "name": "Acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "Diazepam",
          "type": "DRUG"
        },
        {
          "name": "Hydrocodone-Acetaminophen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Henry Ford Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2019-01-22",
      "completion_date": "2020-12-31",
      "has_results": true,
      "last_update_posted_date": "2024-04-02",
      "last_synced_at": "2026-10-02T08:11:59.149Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03818919"
    },
    {
      "nct_id": "NCT03657810",
      "title": "A Controlled Study to Determine the Efficacy and Safety of CL-108 5 mg for Acute Pain and the Prevention of OINV",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pain",
        "Nausea",
        "Vomiting"
      ],
      "interventions": [
        {
          "name": "CL-108 5 mg",
          "type": "DRUG"
        },
        {
          "name": "Norco",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Charleston Laboratories, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 349,
      "start_date": "2017-08-02",
      "completion_date": "2018-11-30",
      "has_results": true,
      "last_update_posted_date": "2023-03-22",
      "last_synced_at": "2026-10-02T08:11:59.149Z",
      "location_count": 5,
      "location_summary": "Phoenix, Arizona • Pasadena, Maryland • Austin, Texas + 2 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Pasadena",
          "state": "Maryland"
        },
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03657810"
    },
    {
      "nct_id": "NCT02110719",
      "title": "Decreasing Narcotics in Advanced Pelvic Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Narcotic Use",
        "Pain",
        "Constipation",
        "Nausea"
      ],
      "interventions": [
        {
          "name": "Celebrex",
          "type": "DRUG"
        },
        {
          "name": "Gabapentin",
          "type": "DRUG"
        },
        {
          "name": "IV acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "oral acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "oral ibuprofen",
          "type": "DRUG"
        },
        {
          "name": "percocet",
          "type": "DRUG"
        },
        {
          "name": "vicodin",
          "type": "DRUG"
        },
        {
          "name": "Oxycodone",
          "type": "DRUG"
        },
        {
          "name": "dilaudid",
          "type": "DRUG"
        },
        {
          "name": "Dexamethasone",
          "type": "DRUG"
        },
        {
          "name": "zofran",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Hartford Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 100 Years · Female only"
      },
      "enrollment_count": 138,
      "start_date": "2014-03",
      "completion_date": "2016-06",
      "has_results": false,
      "last_update_posted_date": "2016-08-17",
      "last_synced_at": "2026-10-02T08:11:59.149Z",
      "location_count": 1,
      "location_summary": "Hartford, Connecticut",
      "locations": [
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02110719"
    },
    {
      "nct_id": "NCT04149964",
      "title": "Postoperative Pain Control in Septum and Sinus Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Post-operative Pain",
        "Sinus Surgery"
      ],
      "interventions": [
        {
          "name": "Acetaminophen 325 mg Oral Tablet",
          "type": "DRUG"
        },
        {
          "name": "Acetaminophen 650 mg Oral Tablet",
          "type": "DRUG"
        },
        {
          "name": "OxyCODONE 5 mg Oral Tablet",
          "type": "DRUG"
        },
        {
          "name": "Acetaminophen/Hydrocodone 325 mg/7.5 mg oral tablet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Corewell Health East",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2019-11-27",
      "completion_date": "2022-09-21",
      "has_results": true,
      "last_update_posted_date": "2023-08-31",
      "last_synced_at": "2026-10-02T08:11:59.149Z",
      "location_count": 1,
      "location_summary": "Farmington Hills, Michigan",
      "locations": [
        {
          "city": "Farmington Hills",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04149964"
    },
    {
      "nct_id": "NCT02153177",
      "title": "The Effect of NSAIDs After a Rotator Cuff Repair Surgery.",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Rotator Cuff Tear"
      ],
      "interventions": [
        {
          "name": "Rotator cuff repair",
          "type": "PROCEDURE"
        },
        {
          "name": "Ibuprofen, Hydrocodone/Acetaminophen, Omeprazole",
          "type": "DRUG"
        },
        {
          "name": "Hydrocodone/Acetaminophen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "45 Years to 75 Years"
      },
      "enrollment_count": 0,
      "start_date": "2015-01",
      "completion_date": "2018-12",
      "has_results": false,
      "last_update_posted_date": "2023-02-23",
      "last_synced_at": "2026-10-02T08:11:59.149Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02153177"
    }
  ]
}