{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Normal+fluid+volume&page=2",
    "query": {
      "intervention": "Normal fluid volume",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Normal+fluid+volume&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-11T08:55:37.784Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04177225",
      "title": "Effect of Diastolic Dysfunction on Dynamic Cardiac Monitors",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Stroke Volume Variation",
        "Diastolic Dysfunction"
      ],
      "interventions": [
        {
          "name": "Trans thoracic Ultrasound Examination",
          "type": "PROCEDURE"
        },
        {
          "name": "Intravenous fluid administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2019-02-07",
      "completion_date": "2021-02-01",
      "has_results": false,
      "last_update_posted_date": "2021-02-12",
      "last_synced_at": "2026-09-11T08:55:37.784Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04177225"
    },
    {
      "nct_id": "NCT02788188",
      "title": "Safety, Tolerability, and Pharmacokinetics of SAB-301 in Healthy Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Middle East Respiratory Syndrome Coronavirus"
      ],
      "interventions": [
        {
          "name": "SAB-301",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Normal (9%) Saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 38,
      "start_date": "2016-05-28",
      "completion_date": "2018-04-30",
      "has_results": true,
      "last_update_posted_date": "2018-06-12",
      "last_synced_at": "2026-09-11T08:55:37.784Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02788188"
    },
    {
      "nct_id": "NCT00309842",
      "title": "Myeloablative Umbilical Cord Blood Transplantation in Hematological Diseases",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Myeloid Leukemia",
        "Acute Lymphocytic Leukemia",
        "Chronic Myelogenous Leukemia",
        "Myelofibrosis",
        "MDS",
        "Refractory Anemia",
        "Chronic Lymphocytic Leukemia",
        "Prolymphocytic Leukemia",
        "Non-Hodgkin's Lymphoma",
        "Leukemia",
        "Lymphoma",
        "Multiple Myeloma",
        "Myelodysplastic Syndromes"
      ],
      "interventions": [
        {
          "name": "filgrastim",
          "type": "BIOLOGICAL"
        },
        {
          "name": "cyclophosphamide",
          "type": "DRUG"
        },
        {
          "name": "cyclosporine",
          "type": "DRUG"
        },
        {
          "name": "fludarabine phosphate",
          "type": "DRUG"
        },
        {
          "name": "mycophenolate mofetil",
          "type": "DRUG"
        },
        {
          "name": "umbilical cord blood transplantation",
          "type": "PROCEDURE"
        },
        {
          "name": "total-body irradiation",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG",
        "PROCEDURE",
        "RADIATION"
      ],
      "sponsor": "Masonic Cancer Center, University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "Up to 55 Years"
      },
      "enrollment_count": 213,
      "start_date": "2005-07-28",
      "completion_date": "2019-11-22",
      "has_results": true,
      "last_update_posted_date": "2020-09-10",
      "last_synced_at": "2026-09-11T08:55:37.784Z",
      "location_count": 2,
      "location_summary": "Minneapolis, Minnesota • Seattle, Washington",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00309842"
    },
    {
      "nct_id": "NCT04326036",
      "title": "Use of cSVF Via IV Deployment for Residual Lung Damage After Symptomatic COVID-19 Infection",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Pulmonary Alveolar Proteinosis",
        "COPD",
        "Idiopathic Pulmonary Fibrosis",
        "Viral Pneumonia",
        "Coronavirus Infection",
        "Interstitial Lung Disease"
      ],
      "interventions": [
        {
          "name": "Microcannula Harvest Adipose Derived tissue stromal vascular fraction (tSVF)",
          "type": "PROCEDURE"
        },
        {
          "name": "Centricyte 1000",
          "type": "DEVICE"
        },
        {
          "name": "IV Deployment Of cSVF In Sterile Normal Saline IV Solution",
          "type": "PROCEDURE"
        },
        {
          "name": "Liberase Enzyme (Roche)",
          "type": "DRUG"
        },
        {
          "name": "Sterile Normal Saline for Intravenous Use",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Black Tie Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 10,
      "start_date": "2020-03-25",
      "completion_date": "2024-01-31",
      "has_results": false,
      "last_update_posted_date": "2023-02-22",
      "last_synced_at": "2026-09-11T08:55:37.784Z",
      "location_count": 1,
      "location_summary": "Stevensville, Montana",
      "locations": [
        {
          "city": "Stevensville",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04326036"
    },
    {
      "nct_id": "NCT04201704",
      "title": "Effect of Giving Reduced Fluid in Children After Trauma",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critical Illness",
        "Pediatrics",
        "General Surgery",
        "Fluid Therapy",
        "Wounds and Injuries"
      ],
      "interventions": [
        {
          "name": "Balanced crystalloid solution volume administration",
          "type": "OTHER"
        },
        {
          "name": "Packed Erythrocytes Units, Blood Product Unit volume",
          "type": "OTHER"
        },
        {
          "name": "Plasma volume",
          "type": "OTHER"
        },
        {
          "name": "Platelets volume",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "15 Years",
        "sex": "ALL",
        "summary": "6 Months to 15 Years"
      },
      "enrollment_count": 250,
      "start_date": "2018-08-27",
      "completion_date": "2027-09",
      "has_results": false,
      "last_update_posted_date": "2026-05-07",
      "last_synced_at": "2026-09-11T08:55:37.784Z",
      "location_count": 4,
      "location_summary": "Buffalo, New York • New York, New York • Rochester, New York + 1 more",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Rochester",
          "state": "New York"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04201704"
    },
    {
      "nct_id": "NCT01128413",
      "title": "Emergency Department (ED) Flow-directed Fluid Optimization Resuscitation Trial (EFFORT)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Shock"
      ],
      "interventions": [
        {
          "name": "Cheetah NICOM® PLRT",
          "type": "DEVICE"
        },
        {
          "name": "USCOM ® (Ultrasound Cardiac Output Monitor)",
          "type": "DEVICE"
        },
        {
          "name": "Inferior Vena Cava (IVC) Ultrasound Collapsibility",
          "type": "DEVICE"
        },
        {
          "name": "CURVES Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Lactate Clearance",
          "type": "BIOLOGICAL"
        },
        {
          "name": "500ml Normal Saline Bolus",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Clinician Discretion Intravenous Fluid Management",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL",
        "BIOLOGICAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2010-07",
      "completion_date": "2013-11",
      "has_results": true,
      "last_update_posted_date": "2016-04-01",
      "last_synced_at": "2026-09-11T08:55:37.784Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01128413"
    },
    {
      "nct_id": "NCT00354172",
      "title": "Donor Umbilical Cord Blood Natural Killer Cells, Aldesleukin and Umbilical Cord Blood Transplant in Patients With Refractory Hematologic Cancers.",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Leukemia",
        "Myelodysplastic Syndromes"
      ],
      "interventions": [
        {
          "name": "aldesleukin",
          "type": "BIOLOGICAL"
        },
        {
          "name": "filgrastim",
          "type": "BIOLOGICAL"
        },
        {
          "name": "natural killer cell (NK) therapy",
          "type": "BIOLOGICAL"
        },
        {
          "name": "cyclophosphamide",
          "type": "DRUG"
        },
        {
          "name": "cyclosporine",
          "type": "DRUG"
        },
        {
          "name": "fludarabine phosphate",
          "type": "DRUG"
        },
        {
          "name": "methylprednisolone",
          "type": "DRUG"
        },
        {
          "name": "mycophenolate mofetil",
          "type": "DRUG"
        },
        {
          "name": "Umbilical Cord Blood Transplantation (UCBT)",
          "type": "PROCEDURE"
        },
        {
          "name": "Total body irradiation (TBI)",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG",
        "PROCEDURE",
        "RADIATION"
      ],
      "sponsor": "Masonic Cancer Center, University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "Up to 45 Years"
      },
      "enrollment_count": 16,
      "start_date": "2006-02",
      "completion_date": "2008-08",
      "has_results": true,
      "last_update_posted_date": "2017-12-28",
      "last_synced_at": "2026-09-11T08:55:37.784Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00354172"
    },
    {
      "nct_id": "NCT01286168",
      "title": "Trial of Drain Antisepsis After Tissue Expander Breast Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Nonmalignant Breast Conditions",
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Sodium hypochlorite (Dakin's Solution)",
          "type": "DEVICE"
        },
        {
          "name": "Chlorhexidine gluconate disk",
          "type": "DEVICE"
        },
        {
          "name": "Control",
          "type": "PROCEDURE"
        },
        {
          "name": "Occlusive Adhesive Dressing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 110,
      "start_date": "2011-05",
      "completion_date": "2013-11",
      "has_results": true,
      "last_update_posted_date": "2014-12-19",
      "last_synced_at": "2026-09-11T08:55:37.784Z",
      "location_count": 2,
      "location_summary": "San Francisco, California • Rochester, Minnesota",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01286168"
    },
    {
      "nct_id": "NCT04468958",
      "title": "Safety, Tolerability, and Pharmacokinetics of SAB-185 in Healthy Participants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "COVID-19",
        "SARS-CoV2"
      ],
      "interventions": [
        {
          "name": "SAB-185",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Normal saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "SAb Biotherapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 28,
      "start_date": "2020-07-01",
      "completion_date": "2020-12-23",
      "has_results": false,
      "last_update_posted_date": "2022-07-01",
      "last_synced_at": "2026-09-11T08:55:37.784Z",
      "location_count": 3,
      "location_summary": "Wichita, Kansas • Syracuse, New York • San Antonio, Texas",
      "locations": [
        {
          "city": "Wichita",
          "state": "Kansas"
        },
        {
          "city": "Syracuse",
          "state": "New York"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04468958"
    },
    {
      "nct_id": "NCT07089758",
      "title": "A Study for Cerebral Open Flow Microperfusion",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Glioma",
        "Glioblastoma"
      ],
      "interventions": [
        {
          "name": "Cerebral open flow microperfusion",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2026-10",
      "completion_date": "2028-10",
      "has_results": false,
      "last_update_posted_date": "2026-03-23",
      "last_synced_at": "2026-09-11T08:55:37.784Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07089758"
    }
  ]
}