{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Normal+saline+and+epinephrine&page=2", "query": { "intervention": "Normal saline and epinephrine", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Normal+saline+and+epinephrine&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-28T10:55:00.002Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06995352", "title": "Liposomal Bupivacaine Versus Continuous Peripheral Nerve Blocks for Analgesia Following Ankle Surgery", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Moderate-to-severely Painful Ankle Surgery" ], "interventions": [ { "name": "Popliteal nerve block including liposomal bupivacaine", "type": "DRUG" }, { "name": "Adductor canal nerve block including liposomal bupivacaine", "type": "DRUG" }, { "name": "Continuous popliteal nerve block with normal saline", "type": "DRUG" }, { "name": "Popliteal nerve block with exclusively unencapsulated bupivacaine", "type": "DRUG" }, { "name": "Adductor canal nerve block with exclusively unencapsulated bupivacaine", "type": "DRUG" }, { "name": "Continuous popliteal nerve block with unencapsulated bupivacaine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, San Diego", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 140, "start_date": "2025-06-23", "completion_date": "2027-06-22", "has_results": false, "last_update_posted_date": "2026-09-16", "last_synced_at": "2026-09-28T10:55:00.002Z", "location_count": 1, "location_summary": "La Jolla, California", "locations": [ { "city": "La Jolla", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06995352" }, { "nct_id": "NCT03389555", "title": "Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Sepsis", "Septic Shock", "Metabolic Disturbance" ], "interventions": [ { "name": "vitamin C, vitamin B1, hydrocortisone", "type": "DRUG" }, { "name": "Normal saline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Beth Israel Deaconess Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 205, "start_date": "2018-02-09", "completion_date": "2020-02-28", "has_results": true, "last_update_posted_date": "2021-02-16", "last_synced_at": "2026-09-28T10:55:00.002Z", "location_count": 13, "location_summary": "Phoenix, Arizona • Boston, Massachusetts • Cambridge, Massachusetts + 6 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Cambridge", "state": "Massachusetts" }, { "city": "Detroit", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT03389555" }, { "nct_id": "NCT05294640", "title": "Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Eyelid Tumor", "Eyelid Bump", "Eyelid Deformity", "Eyelid Abscess", "Eyelid Boil", "Eyelid Papilloma", "Anesthesia, Local", "Ophthalmology" ], "interventions": [ { "name": "0.9% Bacteriostatic Local Anesthetic Injection", "type": "DRUG" }, { "name": "1% Lidocaine with 1:100,000 epinephrine Local Anesthetic Injection", "type": "DRUG" }, { "name": "Eyelid Lesion Removal", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "110 Years", "sex": "ALL", "summary": "18 Years to 110 Years" }, "enrollment_count": 95, "start_date": "2022-05-17", "completion_date": "2023-02-21", "has_results": true, "last_update_posted_date": "2025-07-08", "last_synced_at": "2026-09-28T10:55:00.002Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05294640" }, { "nct_id": "NCT01916590", "title": "Effectiveness of Continuous Femoral Nerve Block Versus Single Shot Femoral Nerve Block for Pain Control", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Post-operative Pain" ], "interventions": [ { "name": "Bupivicaine", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "20 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "20 Years to 75 Years" }, "enrollment_count": 7, "start_date": "2011-07", "completion_date": "2014-05", "has_results": true, "last_update_posted_date": "2016-08-01", "last_synced_at": "2026-09-28T10:55:00.002Z", "location_count": 1, "location_summary": "Aurora, Colorado", "locations": [ { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT01916590" }, { "nct_id": "NCT02967172", "title": "Efficacy of Multimodal Periarticular Injections in Operatively Treated Ankle Fractures", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Pain, Postoperative", "Ankle Fractures" ], "interventions": [ { "name": "Ropivacaine", "type": "DRUG" }, { "name": "Epinephrine", "type": "DRUG" }, { "name": "Morphine", "type": "DRUG" }, { "name": "0.9% sodium chloride solution", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Iowa", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 100, "start_date": "2016-10", "completion_date": "2018-09-21", "has_results": true, "last_update_posted_date": "2023-12-15", "last_synced_at": "2026-09-28T10:55:00.002Z", "location_count": 1, "location_summary": "Iowa City, Iowa", "locations": [ { "city": "Iowa City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT02967172" }, { "nct_id": "NCT05846399", "title": "CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Cat Bite", "Hand Injuries", "Arm Injury", "Infection, Bacterial", "Anti-bacterial Agents" ], "interventions": [ { "name": "Amoxicillin/clavulanate", "type": "DRUG" }, { "name": "Ciprofloxacin", "type": "DRUG" }, { "name": "Clindamycin", "type": "DRUG" }, { "name": "Placebo (microcrystalline cellulose)", "type": "OTHER" }, { "name": "Wound management", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "OTHER", "PROCEDURE" ], "sponsor": "University of Missouri-Columbia", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 72, "start_date": "2023-09-07", "completion_date": "2027-08-01", "has_results": false, "last_update_posted_date": "2025-10-15", "last_synced_at": "2026-09-28T10:55:00.002Z", "location_count": 1, "location_summary": "Columbia, Missouri", "locations": [ { "city": "Columbia", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT05846399" }, { "nct_id": "NCT04037605", "title": "Hormonal Mechanisms of Sleep Restriction - Axis Study in Older Men and Postmenopausal Women", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Sleep Restriction" ], "interventions": [ { "name": "Ketoconazole Pill (also known as nizoral)", "type": "DRUG" }, { "name": "Ganirelix", "type": "DRUG" }, { "name": "Dexamethasone Pill", "type": "DRUG" }, { "name": "Dexamethasone injection", "type": "DRUG" }, { "name": "Cosyntropin Injectable Product", "type": "DRUG" }, { "name": "Recombinant Human Luteinizing Hormone (also known as luveris)", "type": "DRUG" }, { "name": "Hydrocortisone Injection (also known as solu-cortef)", "type": "DRUG" }, { "name": "Gonadorelin (also known as Lutrepulse)", "type": "DRUG" }, { "name": "Corticorelin (also known as Acthrel)", "type": "DRUG" }, { "name": "Placebo oral tablet", "type": "DRUG" }, { "name": "Saline Solution", "type": "DRUG" }, { "name": "Saline solution for injection", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "60 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "60 Years to 80 Years" }, "enrollment_count": 5, "start_date": "2020-02-09", "completion_date": "2026-06-24", "has_results": false, "last_update_posted_date": "2025-09-11", "last_synced_at": "2026-09-28T10:55:00.002Z", "location_count": 1, "location_summary": "Torrance, California", "locations": [ { "city": "Torrance", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04037605" }, { "nct_id": "NCT03840122", "title": "ACB + IPACK Block With or Without Local Infiltration in RA-TKA", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Knee Arthropathy" ], "interventions": [ { "name": "ACB + IPACK block with injection of local anesthetic", "type": "OTHER" }, { "name": "ACB + IPACK block without injection", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Louisville", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 0, "start_date": "2019-10-08", "completion_date": "2019-10-08", "has_results": false, "last_update_posted_date": "2019-10-10", "last_synced_at": "2026-09-28T10:55:00.002Z", "location_count": 1, "location_summary": "Louisville, Kentucky", "locations": [ { "city": "Louisville", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT03840122" }, { "nct_id": "NCT07276906", "title": "Comparing Intramuscular Fentanyl and Ketorolac With Nerve of Arnold (NOA) Block for Bilateral Myringotomy", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Postoperative Pain" ], "interventions": [ { "name": "Fentanyl", "type": "DRUG" }, { "name": "Ketorolac", "type": "DRUG" }, { "name": "Nerve of Arnold Block", "type": "PROCEDURE" }, { "name": "Sham Intramuscular Injection", "type": "PROCEDURE" }, { "name": "Sham Nerve of Arnold Block", "type": "PROCEDURE" }, { "name": "Dexmedetomidine", "type": "DRUG" }, { "name": "Bupivacaine", "type": "DRUG" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "University of South Alabama", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Months", "maximum_age": "6 Years", "sex": "ALL", "summary": "6 Months to 6 Years" }, "enrollment_count": 300, "start_date": "2026-01", "completion_date": "2026-08", "has_results": false, "last_update_posted_date": "2025-12-11", "last_synced_at": "2026-09-28T10:55:00.002Z", "location_count": 1, "location_summary": "Mobile, Alabama", "locations": [ { "city": "Mobile", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT07276906" }, { "nct_id": "NCT01595386", "title": "Effect of Postop Steroids on Cardiovascular/Respiratory Function in Neonates Undergoing Cardiopulmonary Bypass", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Heart Disease Congenital Complex" ], "interventions": [ { "name": "Hydrocortisone", "type": "DRUG" }, { "name": "Normal Saline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Alabama at Birmingham", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Day", "maximum_age": "28 Days", "sex": "ALL", "summary": "1 Day to 28 Days" }, "enrollment_count": 40, "start_date": "2012-04", "completion_date": "2013-11", "has_results": true, "last_update_posted_date": "2015-11-10", "last_synced_at": "2026-09-28T10:55:00.002Z", "location_count": 1, "location_summary": "Birmingham, Alabama", "locations": [ { "city": "Birmingham", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT01595386" } ] }