{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Normal+saline+as+placebo+comparator&page=5", "query": { "intervention": "Normal saline as placebo comparator", "page": 5 }, "page_size": 10 }, "pagination": { "page": 5, "page_size": 10, "total_count": 942, "total_pages": 95, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Normal+saline+as+placebo+comparator&page=6&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Normal+saline+as+placebo+comparator&page=4&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-07T18:31:53.911Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01667120", "title": "The Use of Ketorolac in Surgical Neonates", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Postoperative Pain Control in Surgical Neonates" ], "interventions": [ { "name": "Ketorolac", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Nationwide Children's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Week", "maximum_age": "3 Months", "sex": "ALL", "summary": "1 Week to 3 Months" }, "enrollment_count": 0, "start_date": "2012-07", "completion_date": "2018-12-31", "has_results": false, "last_update_posted_date": "2025-10-29", "last_synced_at": "2026-10-07T18:31:53.911Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01667120" }, { "nct_id": "NCT01381549", "title": "GSK2251052 in Complicated Urinary Tract Infection", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Infections, Urinary Tract" ], "interventions": [ { "name": "GSK2251052", "type": "DRUG" }, { "name": "imipenem-cilastatin", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2011-06-28", "completion_date": "2012-03-06", "has_results": true, "last_update_posted_date": "2017-09-08", "last_synced_at": "2026-10-07T18:31:53.911Z", "location_count": 4, "location_summary": "Los Angeles, California • Council Bluffs, Iowa • Topeka, Kansas + 1 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Council Bluffs", "state": "Iowa" }, { "city": "Topeka", "state": "Kansas" }, { "city": "Corsicana", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01381549" }, { "nct_id": "NCT03066778", "title": "A Study of Pembrolizumab (MK-3475) in Combination With Etoposide/Platinum (Cisplatin or Carboplatin) for Participants With Extensive Stage Small Cell Lung Cancer (MK-3475-604/KEYNOTE-604)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Small Cell Lung Cancer (SCLC)" ], "interventions": [ { "name": "Pembrolizumab", "type": "BIOLOGICAL" }, { "name": "Normal saline solution", "type": "DRUG" }, { "name": "Carboplatin", "type": "DRUG" }, { "name": "Cisplatin", "type": "DRUG" }, { "name": "Etoposide", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Merck Sharp & Dohme LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 453, "start_date": "2017-05-02", "completion_date": "2021-09-21", "has_results": true, "last_update_posted_date": "2022-10-03", "last_synced_at": "2026-10-07T18:31:53.911Z", "location_count": 27, "location_summary": "Miami, Florida • Chicago, Illinois • Evanston, Illinois + 21 more", "locations": [ { "city": "Miami", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Evanston", "state": "Illinois" }, { "city": "Munster", "state": "Indiana" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT03066778" }, { "nct_id": "NCT06503978", "title": "Microbiota Transplant Therapy for Children With Both Autism Spectrum Disorder and Gastrointestinal Disorders", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Autism Spectrum Disorder", "Gastro-Intestinal Disorder", "Constipation", "Diarrhea" ], "interventions": [ { "name": "MTP-101P", "type": "COMBINATION_PRODUCT" }, { "name": "Vancomycin", "type": "COMBINATION_PRODUCT" }, { "name": "Miralax", "type": "COMBINATION_PRODUCT" }, { "name": "Antacid", "type": "COMBINATION_PRODUCT" }, { "name": "Placebo MTP-101P", "type": "COMBINATION_PRODUCT" }, { "name": "Placebo Vancomycin", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "COMBINATION_PRODUCT" ], "sponsor": "Gut-Brain-Axis Therapeutics Inc.", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "4 Years", "maximum_age": "18 Years", "sex": "ALL", "summary": "4 Years to 18 Years" }, "enrollment_count": 60, "start_date": "2024-08-20", "completion_date": "2026-08-17", "has_results": false, "last_update_posted_date": "2024-09-25", "last_synced_at": "2026-10-07T18:31:53.911Z", "location_count": 1, "location_summary": "Tempe, Arizona", "locations": [ { "city": "Tempe", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT06503978" }, { "nct_id": "NCT04502693", "title": "Effectiveness of GlaxoSmithKline Biologicals S.A's Meningococcal Group B and Combined ABCWY Vaccines in Healthy Adolescents and Young Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Infections, Meningococcal" ], "interventions": [ { "name": "rMenB+OMV NZ vaccine", "type": "COMBINATION_PRODUCT" }, { "name": "Meningococcal Groups A, C, W and Y Conjugate Vaccine (MenACWY)", "type": "BIOLOGICAL" }, { "name": "Placebo", "type": "COMBINATION_PRODUCT" }, { "name": "MenABCWY-1", "type": "COMBINATION_PRODUCT" }, { "name": "MenABCWY-2", "type": "COMBINATION_PRODUCT" }, { "name": "MenABCWY-3", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "COMBINATION_PRODUCT", "BIOLOGICAL" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "10 Years", "maximum_age": "25 Years", "sex": "ALL", "summary": "10 Years to 25 Years" }, "enrollment_count": 3657, "start_date": "2020-08-14", "completion_date": "2022-09-13", "has_results": true, "last_update_posted_date": "2024-03-05", "last_synced_at": "2026-10-07T18:31:53.911Z", "location_count": 64, "location_summary": "Chandler, Arizona • Glendale, Arizona • Jonesboro, Arkansas + 51 more", "locations": [ { "city": "Chandler", "state": "Arizona" }, { "city": "Glendale", "state": "Arizona" }, { "city": "Jonesboro", "state": "Arkansas" }, { "city": "Bell Gardens", "state": "California" }, { "city": "Canoga Park", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04502693" }, { "nct_id": "NCT01544998", "title": "Tadalafil and Nesiritide as Therapy in Pre-clinical Heart Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Congestive Heart Failure" ], "interventions": [ { "name": "Nesiritide", "type": "DRUG" }, { "name": "Tadalafil", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Saline load", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "21 Years to 90 Years" }, "enrollment_count": 43, "start_date": "2012-02", "completion_date": "2014-08", "has_results": true, "last_update_posted_date": "2018-03-22", "last_synced_at": "2026-10-07T18:31:53.911Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT01544998" }, { "nct_id": "NCT07160244", "title": "BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Multivalent Group B streptococcus vaccine", "type": "BIOLOGICAL" }, { "name": "Placebo", "type": "BIOLOGICAL" }, { "name": "Infanrix hexa", "type": "BIOLOGICAL" }, { "name": "Prevenar 20", "type": "BIOLOGICAL" }, { "name": "Pediarix", "type": "BIOLOGICAL" }, { "name": "Prevnar 20", "type": "BIOLOGICAL" }, { "name": "Infanrix", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "1 Day", "maximum_age": "49 Years", "sex": "ALL", "summary": "1 Day to 49 Years" }, "enrollment_count": 6000, "start_date": "2025-08-25", "completion_date": "2029-03-02", "has_results": false, "last_update_posted_date": "2026-09-25", "last_synced_at": "2026-10-07T18:31:53.911Z", "location_count": 120, "location_summary": "Birmingham, Alabama • Dothan, Alabama • Mobile, Alabama + 56 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Dothan", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT07160244" }, { "nct_id": "NCT02354859", "title": "A Phase 2 IV Gallium Study for Patients With Cystic Fibrosis (IGNITE Study)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cystic Fibrosis" ], "interventions": [ { "name": "Gallium nitrate", "type": "DRUG" }, { "name": "Normal Saline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 119, "start_date": "2016-03", "completion_date": "2018-02-01", "has_results": true, "last_update_posted_date": "2019-03-21", "last_synced_at": "2026-10-07T18:31:53.911Z", "location_count": 23, "location_summary": "Birmingham, Alabama • La Jolla, California • Denver, Colorado + 20 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "La Jolla", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02354859" }, { "nct_id": "NCT02873819", "title": "Safety and Efficacy Study of GL-0817 (With Cyclophosphamide) for the Prevention of Recurrence of Squamous Cell Carcinoma of the Oral Cavity", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Squamous Cell Carcinoma of the Oral Cavity" ], "interventions": [ { "name": "GL-0817", "type": "DRUG" }, { "name": "Hiltonol", "type": "DRUG" }, { "name": "Sargramostim", "type": "DRUG" }, { "name": "cyclophosphamide", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Gliknik Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 80, "start_date": "2017-03-30", "completion_date": "2021-05-25", "has_results": false, "last_update_posted_date": "2022-03-08", "last_synced_at": "2026-10-07T18:31:53.911Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT02873819" }, { "nct_id": "NCT05233566", "title": "Ketamine for Postoperative Avoidance of Depressive Symptoms: The K-PASS Feasibility Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Postoperative Depression" ], "interventions": [ { "name": "Ketamine", "type": "DRUG" }, { "name": "Normal saline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 32, "start_date": "2022-04-25", "completion_date": "2023-03-08", "has_results": true, "last_update_posted_date": "2026-08-21", "last_synced_at": "2026-10-07T18:31:53.911Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT05233566" } ] }