{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Normal+saline+solution&page=80", "query": { "intervention": "Normal saline solution", "page": 80 }, "page_size": 10 }, "pagination": { "page": 80, "page_size": 10, "total_count": 2691, "total_pages": 270, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Normal+saline+solution&page=81&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Normal+saline+solution&page=79&page_size=10" }, "source": "remote", "last_synced_at": "2026-11-06T01:53:53.543Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00419991", "title": "Open Label Non-comparative Clinical Trial of Tigecycline in Patients With Catheter Infection", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Staphylococcal Infections" ], "interventions": [ { "name": "Tigecycline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "CPL Associates", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 10, "start_date": "2007-01", "completion_date": "2008-05", "has_results": false, "last_update_posted_date": "2011-06-22", "last_synced_at": "2026-11-06T01:53:53.543Z", "location_count": 3, "location_summary": "Huntsville, Alabama • Marietta, Georgia • Cumberland, Maryland", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Marietta", "state": "Georgia" }, { "city": "Cumberland", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00419991" }, { "nct_id": "NCT00775658", "title": "Olopatadine Eye Drops and Allergy Skin Testing", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Allergic Rhinitis", "Allergic Conjunctivitis" ], "interventions": [ { "name": "olopatadine", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 24, "start_date": "2008-01", "completion_date": "2008-06", "has_results": true, "last_update_posted_date": "2017-07-12", "last_synced_at": "2026-11-06T01:53:53.543Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00775658" }, { "nct_id": "NCT01960348", "title": "APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "TTR-mediated Amyloidosis", "Amyloidosis, Hereditary", "Amyloid Neuropathies, Familial", "Familial Amyloid Polyneuropathies", "Amyloid Neuropathies", "Amyloidosis, Hereditary, Transthyretin-Related" ], "interventions": [ { "name": "patisiran (ALN-TTR02)", "type": "DRUG" }, { "name": "Sterile Normal Saline (0.9% NaCl)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Alnylam Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 225, "start_date": "2013-11", "completion_date": "2017-08", "has_results": true, "last_update_posted_date": "2024-04-22", "last_synced_at": "2026-11-06T01:53:53.543Z", "location_count": 13, "location_summary": "La Mesa, California • Orange, California • Denver, Colorado + 9 more", "locations": [ { "city": "La Mesa", "state": "California" }, { "city": "Orange", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT01960348" }, { "nct_id": "NCT04210115", "title": "Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Esophageal Squamous Cell Carcinoma (ESCC)", "Gastroesophageal Junction Carcinoma (GEJC)", "Esophageal Adenocarcinoma (EAC)" ], "interventions": [ { "name": "pembrolizumab", "type": "BIOLOGICAL" }, { "name": "placebo", "type": "DRUG" }, { "name": "cisplatin", "type": "DRUG" }, { "name": "5-FU", "type": "DRUG" }, { "name": "radiotherapy", "type": "RADIATION" }, { "name": "leucovorin", "type": "DRUG" }, { "name": "levoleucovorin", "type": "DRUG" }, { "name": "oxaliplatin", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG", "RADIATION" ], "sponsor": "Merck Sharp & Dohme LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 703, "start_date": "2020-02-28", "completion_date": "2026-06-26", "has_results": false, "last_update_posted_date": "2026-10-30", "last_synced_at": "2026-11-06T01:53:53.543Z", "location_count": 19, "location_summary": "Long Beach, California • Columbus, Georgia • Westwood, Kansas + 16 more", "locations": [ { "city": "Long Beach", "state": "California" }, { "city": "Columbus", "state": "Georgia" }, { "city": "Westwood", "state": "Kansas" }, { "city": "Wichita", "state": "Kansas" }, { "city": "New Orleans", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT04210115" }, { "nct_id": "NCT01913340", "title": "Neonatal Erythropoietin And Therapeutic Hypothermia Outcomes in Newborn Brain Injury (NEATO)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Hypoxic-ischemic Encephalopathy", "Neonatal Encephalopathy", "Birth Asphyxia" ], "interventions": [ { "name": "Erythropoietin", "type": "DRUG" }, { "name": "Normal saline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Minutes", "maximum_age": "24 Hours", "sex": "ALL", "summary": "30 Minutes to 24 Hours" }, "enrollment_count": 50, "start_date": "2013-09", "completion_date": "2016-09", "has_results": true, "last_update_posted_date": "2020-07-13", "last_synced_at": "2026-11-06T01:53:53.543Z", "location_count": 7, "location_summary": "Little Rock, Arkansas • Palo Alto, California • San Francisco, California + 4 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Palo Alto", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Santa Clara", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" } ], "official_url": "https://clinicaltrials.gov/study/NCT01913340" }, { "nct_id": "NCT02810340", "title": "Study of Meninigococcal Conjugate Vaccine Containing Serogroups A,C,Y,W and X (MCV5) in Healthy Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Meningococcal Vaccines" ], "interventions": [ { "name": "Adjuvanted MCV-5", "type": "BIOLOGICAL" }, { "name": "Non-Adjuvanted MCV-5", "type": "BIOLOGICAL" }, { "name": "Menactra®", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "PATH", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": 60, "start_date": "2016-08-01", "completion_date": "2017-10-13", "has_results": true, "last_update_posted_date": "2021-06-09", "last_synced_at": "2026-11-06T01:53:53.543Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT02810340" }, { "nct_id": "NCT05283850", "title": "Surviving PEA in Roanoke (SPEAR) Study", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Cardiac Arrest", "Pulseless Electrical Activity" ], "interventions": [ { "name": "High Calcium, Low Sodium (HCLS) Crystalloid Therapy", "type": "DRUG" }, { "name": "High Calcium, High Sodium (HCHS) Crystalloid Therapy", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Carol Bernier", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 342, "start_date": "2022-02-16", "completion_date": "2027-02", "has_results": false, "last_update_posted_date": "2022-03-17", "last_synced_at": "2026-11-06T01:53:53.543Z", "location_count": 1, "location_summary": "Roanoke, Virginia", "locations": [ { "city": "Roanoke", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT05283850" }, { "nct_id": "NCT03213249", "title": "Bacterial Biofilms in Reconstructive Breast Prostheses Following Mastectomy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Breast Implant Infection", "Mammoplasty" ], "interventions": [ { "name": "Normal saline", "type": "OTHER" }, { "name": "Cefazolin", "type": "DRUG" }, { "name": "Skin biopsy", "type": "PROCEDURE" }, { "name": "Bilateral skin- or nipple-sparing mastectomies", "type": "PROCEDURE" }, { "name": "Tissue expander", "type": "DEVICE" }, { "name": "Breast implant", "type": "DEVICE" }, { "name": "Autologous flap", "type": "PROCEDURE" }, { "name": "Acellular dermal matrix sling", "type": "OTHER" }, { "name": "Gentamicin", "type": "DRUG" }, { "name": "Bacitracin", "type": "DRUG" } ], "intervention_types": [ "OTHER", "DRUG", "PROCEDURE", "DEVICE" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "FEMALE", "summary": "18 Years to 75 Years · Female only" }, "enrollment_count": 19, "start_date": "2017-07-25", "completion_date": "2018-09-26", "has_results": false, "last_update_posted_date": "2019-02-08", "last_synced_at": "2026-11-06T01:53:53.543Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT03213249" }, { "nct_id": "NCT02175225", "title": "Intracerebral Hemorrhage Deferoxamine Trial - iDEF Ttrial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Intracerebral Hemorrhage" ], "interventions": [ { "name": "Deferoxamine Mesylate", "type": "DRUG" }, { "name": "Placebo (for Deferoxamine Mesylate)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Beth Israel Deaconess Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 294, "start_date": "2014-10", "completion_date": "2018-05-30", "has_results": true, "last_update_posted_date": "2019-05-30", "last_synced_at": "2026-11-06T01:53:53.543Z", "location_count": 25, "location_summary": "Phoenix, Arizona • Palo Alto, California • San Francisco, California + 18 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Palo Alto", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "New Haven", "state": "Connecticut" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02175225" }, { "nct_id": "NCT00657540", "title": "Black Widow Spider Antivenin for Patients With Systemic Latrodectism", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Latrodectism" ], "interventions": [ { "name": "Analatro", "type": "DRUG" }, { "name": "Saline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Instituto Bioclon S.A. de C.V.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "10 Years", "maximum_age": null, "sex": "ALL", "summary": "10 Years and older" }, "enrollment_count": 60, "start_date": "2009-10", "completion_date": "2014-10", "has_results": true, "last_update_posted_date": "2018-04-03", "last_synced_at": "2026-11-06T01:53:53.543Z", "location_count": 16, "location_summary": "Phoenix, Arizona • Davis, California • Fresno, California + 11 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Davis", "state": "California" }, { "city": "Fresno", "state": "California" }, { "city": "Irvine", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00657540" } ] }