{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Normosol",
    "query": {
      "intervention": "Normosol"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-02T17:03:25.339Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03054922",
      "title": "Impact of Intraoperative Fluid Management on Electrolyte and Acid-base Variables",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Anesthesia"
      ],
      "interventions": [
        {
          "name": "Normal Saline",
          "type": "DRUG"
        },
        {
          "name": "Lactated Ringer",
          "type": "DRUG"
        },
        {
          "name": "Normosol-R Inj",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Nationwide Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "10 Years to 21 Years"
      },
      "enrollment_count": 59,
      "start_date": "2017-02-23",
      "completion_date": "2018-09-30",
      "has_results": true,
      "last_update_posted_date": "2020-03-25",
      "last_synced_at": "2026-09-02T17:03:25.339Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03054922"
    },
    {
      "nct_id": "NCT01606787",
      "title": "Mannitol Use During Partial Nephrectomy Prior to Renal Ischemia and Impact on Renal Function Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Renal Cancer"
      ],
      "interventions": [
        {
          "name": "mannitol",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 210,
      "start_date": "2012-05-22",
      "completion_date": "2018-02",
      "has_results": true,
      "last_update_posted_date": "2018-10-15",
      "last_synced_at": "2026-09-02T17:03:25.339Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01606787"
    },
    {
      "nct_id": "NCT06822374",
      "title": "Hypertonic Saline in Posterior Spinal Fusion",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Scoliosis Idiopathic",
        "Scoliosis;Congenital"
      ],
      "interventions": [
        {
          "name": "Normosol-R",
          "type": "DRUG"
        },
        {
          "name": "buffered 2% hypertonic saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Joseph D. Tobias",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "10 Years to 25 Years"
      },
      "enrollment_count": 0,
      "start_date": "2025-12",
      "completion_date": "2028-05",
      "has_results": false,
      "last_update_posted_date": "2025-11-10",
      "last_synced_at": "2026-09-02T17:03:25.339Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06822374"
    },
    {
      "nct_id": "NCT00389311",
      "title": "A Pilot Study for Toxicity Evaluation of HIV Rectal Microbicides",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "Normosol-R",
          "type": "DRUG"
        },
        {
          "name": "Nonoxynol-9",
          "type": "DRUG"
        },
        {
          "name": "Gastrointestinal instrumentation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "21 Years and older · Male only"
      },
      "enrollment_count": 12,
      "start_date": "2007-04",
      "completion_date": "2009-06",
      "has_results": false,
      "last_update_posted_date": "2015-04-01",
      "last_synced_at": "2026-09-02T17:03:25.339Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00389311"
    },
    {
      "nct_id": "NCT00696618",
      "title": "Enema Use and Acceptability in HIV Negative Men Who Have Sex With Men",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "Fleet Enema",
          "type": "DRUG"
        },
        {
          "name": "tap water enema",
          "type": "DRUG"
        },
        {
          "name": "Normosol-R enema",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 9,
      "start_date": "2007-07",
      "completion_date": "2012-03",
      "has_results": true,
      "last_update_posted_date": "2017-04-28",
      "last_synced_at": "2026-09-02T17:03:25.339Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00696618"
    },
    {
      "nct_id": "NCT01058746",
      "title": "Randomized Trial of Restrictive Versus Liberal Perioperative Fluid Management for Patients Undergoing Pancreatic Resection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pancreatic Cancer"
      ],
      "interventions": [
        {
          "name": "restrictive perioperative fluid management",
          "type": "OTHER"
        },
        {
          "name": "Liberal perioperative fluid management",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 331,
      "start_date": "2010-01",
      "completion_date": "2019-09",
      "has_results": false,
      "last_update_posted_date": "2019-09-25",
      "last_synced_at": "2026-09-02T17:03:25.339Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01058746"
    },
    {
      "nct_id": "NCT03537898",
      "title": "Balanced Solutions and Plasma Electrolytes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critical Illness",
        "Acidosis, Metabolic"
      ],
      "interventions": [
        {
          "name": "Lactated Ringer's",
          "type": "OTHER"
        },
        {
          "name": "Normosol",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2093,
      "start_date": "2018-06-01",
      "completion_date": "2019-03-02",
      "has_results": false,
      "last_update_posted_date": "2019-10-11",
      "last_synced_at": "2026-09-02T17:03:25.339Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03537898"
    },
    {
      "nct_id": "NCT07408583",
      "title": "Prenatal Transplantation for Fetuses With Fanconi Anemia",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Fanconi Anemia",
        "Anemia, Hypoplastic, Congenital",
        "Congenital Bone Marrow Failure Syndromes",
        "Bone Marrow Failure Disorders",
        "Genetic Diseases, Inborn",
        "Congenital, Hereditary, and Neonatal Diseases and Abnormalities",
        "DNA Repair-Deficiency Disorders",
        "Cancer Predisposition Syndrome"
      ],
      "interventions": [
        {
          "name": "IUHSCT for FA-affected fetuses",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Agnieszka Czechowicz",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 12,
      "start_date": "2028-01",
      "completion_date": "2033-07",
      "has_results": false,
      "last_update_posted_date": "2026-06-16",
      "last_synced_at": "2026-09-02T17:03:25.339Z",
      "location_count": 2,
      "location_summary": "San Francisco, California • Stanford, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07408583"
    },
    {
      "nct_id": "NCT01053741",
      "title": "Effect of Seminal Fluid on the Colon Wall; Implications for HIV Transmission",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Human Immunodeficiency Virus (HIV)"
      ],
      "interventions": [
        {
          "name": "Radiolabeled autologous seminal fluid",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Radiolabeled Normosol-R",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "21 Years and older · Male only"
      },
      "enrollment_count": 11,
      "start_date": "2008-03",
      "completion_date": "2009-12",
      "has_results": true,
      "last_update_posted_date": "2017-05-25",
      "last_synced_at": "2026-09-02T17:03:25.339Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01053741"
    },
    {
      "nct_id": "NCT02986698",
      "title": "In Utero Hematopoietic Stem Cell Transplantation for Alpha-thalassemia Major (ATM)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Alpha Thalassemia Major",
        "Hemoglobinopathy; With Thalassemia",
        "Hemoglobinopathies",
        "Fetal Anemia",
        "Fetal Hydrops",
        "Alpha; Thalassemia",
        "Thalassemia Major",
        "Thalassemia Alpha",
        "A-Thalassemia"
      ],
      "interventions": [
        {
          "name": "in utero hematopoietic stem cell transplantation",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Weeks",
        "maximum_age": "26 Weeks",
        "sex": "ALL",
        "summary": "18 Weeks to 26 Weeks"
      },
      "enrollment_count": 6,
      "start_date": "2017-10-05",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-01-27",
      "last_synced_at": "2026-09-02T17:03:25.339Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02986698"
    }
  ]
}