{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nose-only+breathing&page=2", "query": { "intervention": "Nose-only breathing", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 60, "total_pages": 6, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nose-only+breathing&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nose-only+breathing&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-01T11:32:39.393Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02074059", "title": "Trial to Assess the Safety and Tolerability of Lucinactant for Inhalation in Premature Neonates", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Respiratory Distress Syndrome" ], "interventions": [ { "name": "Lucinactant for Inhalation", "type": "DRUG" }, { "name": "nCPAP alone", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Windtree Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "29 Weeks", "maximum_age": "34 Weeks", "sex": "ALL", "summary": "29 Weeks to 34 Weeks" }, "enrollment_count": 80, "start_date": "2014-02", "completion_date": "2015-11", "has_results": true, "last_update_posted_date": "2017-04-21", "last_synced_at": "2026-10-01T11:32:39.393Z", "location_count": 11, "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Loma Linda, California + 8 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Loma Linda", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Newark", "state": "Delaware" } ], "official_url": "https://clinicaltrials.gov/study/NCT02074059" }, { "nct_id": "NCT01125748", "title": "A Study Evaluating the Persistency of Response With or Without Xolair (Omalizumab) After Long-term Therapy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Allergic Asthma" ], "interventions": [ { "name": "Omalizumab", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Asthma therapies", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Genentech, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "17 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "17 Years to 70 Years" }, "enrollment_count": 176, "start_date": "2010-05", "completion_date": "2013-08", "has_results": true, "last_update_posted_date": "2014-10-15", "last_synced_at": "2026-10-01T11:32:39.393Z", "location_count": 100, "location_summary": "Huntsville, Alabama • Little Rock, Arkansas • Bakersfield, California + 87 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Bakersfield", "state": "California" }, { "city": "Fresno", "state": "California" }, { "city": "Fresno", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01125748" }, { "nct_id": "NCT05675345", "title": "Physiological Effects of Continuous Negative External Pressure for Acute Hypoxemic Respiratory Failure", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Acute Hypoxemic Respiratory Failure" ], "interventions": [ { "name": "HFNC only", "type": "DEVICE" }, { "name": "HFNC + CNEP10", "type": "DEVICE" }, { "name": "HFNC + CNEP20", "type": "DEVICE" }, { "name": "HFNC + CNEP30", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2024-02-28", "completion_date": "2026-12-31", "has_results": false, "last_update_posted_date": "2024-03-04", "last_synced_at": "2026-10-01T11:32:39.393Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05675345" }, { "nct_id": "NCT05918575", "title": "Postextubation Use of Noninvasive Respiratory Support in Severely Obese Patients", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Obesity, Morbid", "Extubation Failure" ], "interventions": [ { "name": "Noninvasive ventilation alternating with high flow nasal cannula", "type": "DEVICE" }, { "name": "High flow nasal cannula", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Rush University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 250, "start_date": "2023-07-10", "completion_date": "2028-12-01", "has_results": false, "last_update_posted_date": "2026-08-07", "last_synced_at": "2026-10-01T11:32:39.393Z", "location_count": 4, "location_summary": "Chicago, Illinois • Winfield, Illinois • Houston, Texas + 1 more", "locations": [ { "city": "Chicago", "state": "Illinois" }, { "city": "Winfield", "state": "Illinois" }, { "city": "Houston", "state": "Texas" }, { "city": "Milwaukee", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT05918575" }, { "nct_id": "NCT06521502", "title": "The APS Phenotyping Study", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "ARDS", "Sepsis", "Pneumonia" ], "interventions": [ { "name": "Blood collection", "type": "OTHER" }, { "name": "Urine Collection", "type": "OTHER" }, { "name": "Nasal, oral, and rectal swabs", "type": "OTHER" }, { "name": "Stool collection", "type": "OTHER" }, { "name": "Heat Moisture Exchange Filter collection", "type": "OTHER" }, { "name": "Tracheal Aspirate sample collection", "type": "OTHER" }, { "name": "Non-bronchoscopic bronchoalveolar lavage (NBBAL)", "type": "PROCEDURE" }, { "name": "Surveys", "type": "OTHER" }, { "name": "Short physical performance battery", "type": "OTHER" }, { "name": "Hand grip strength", "type": "OTHER" }, { "name": "CNS Vital Signs", "type": "OTHER" }, { "name": "Muscle Ultrasound", "type": "OTHER" }, { "name": "Muscle Strength", "type": "OTHER" }, { "name": "Spirometry", "type": "OTHER" }, { "name": "Lung Diffusion Testing (DLCO)", "type": "OTHER" }, { "name": "Chest CT Scan", "type": "RADIATION" } ], "intervention_types": [ "OTHER", "PROCEDURE", "RADIATION" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 4000, "start_date": "2024-07-25", "completion_date": "2029-04-30", "has_results": false, "last_update_posted_date": "2026-02-20", "last_synced_at": "2026-10-01T11:32:39.393Z", "location_count": 20, "location_summary": "Fresno, California • Palo Alto, California • San Francisco, California + 12 more", "locations": [ { "city": "Fresno", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Denver", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT06521502" }, { "nct_id": "NCT02636868", "title": "The Safety and Efficacy of Lucinactant for Inhalation in Premature Neonates 26 to 32 Weeks Gestational Age", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Respiratory Distress Syndrome" ], "interventions": [ { "name": "Lucinactant delivered via investigational delivery device", "type": "DRUG" }, { "name": "nCPAP", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Windtree Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "26 Weeks", "maximum_age": "32 Weeks", "sex": "ALL", "summary": "26 Weeks to 32 Weeks" }, "enrollment_count": 221, "start_date": "2015-12", "completion_date": "2019-08-06", "has_results": true, "last_update_posted_date": "2021-04-23", "last_synced_at": "2026-10-01T11:32:39.393Z", "location_count": 22, "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Loma Linda, California + 18 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Loma Linda", "state": "California" }, { "city": "Orange", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02636868" }, { "nct_id": "NCT02464696", "title": "Non-invasive Ventilation in Reducing the Need for Intubation in Patients With Cancer and Respiratory Failure", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hematopoietic and Lymphoid Cell Neoplasm", "Malignant Solid Neoplasm" ], "interventions": [ { "name": "Methylprednisolone", "type": "DRUG" }, { "name": "Oxygen Therapy", "type": "PROCEDURE" }, { "name": "Positive Air Pressure Device", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "PROCEDURE", "DEVICE" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 256, "start_date": "2015-10-06", "completion_date": "2026-10-01", "has_results": false, "last_update_posted_date": "2026-09-14", "last_synced_at": "2026-10-01T11:32:39.393Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02464696" }, { "nct_id": "NCT07449715", "title": "Respiration From Pleth Validation", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Respiratory Rate Monitoring" ], "interventions": [ { "name": "Physiological Monitoring with SpO₂ Sensors and Capnography", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Philips Clinical & Medical Affairs Global", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "4 Years", "maximum_age": null, "sex": "ALL", "summary": "4 Years and older" }, "enrollment_count": 113, "start_date": "2026-02-06", "completion_date": "2026-05-25", "has_results": false, "last_update_posted_date": "2026-03-04", "last_synced_at": "2026-10-01T11:32:39.393Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT07449715" }, { "nct_id": "NCT04170062", "title": "Oxygen Savings With Administered Oxygen and High Flow Ambient Air At Rest", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Pulmonary Disease, Chronic Obstructive", "Lung Diseases, Interstitial", "Pulmonary Fibrosis", "Hypoxemia", "Dyspnea", "Oxygen Inhalation Therapy" ], "interventions": [ { "name": "Nasal Delivery of High-Flow Air and Oxygen Therapy", "type": "DEVICE" }, { "name": "Nasal Delivery of Oxygen Therapy", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Johns Hopkins University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "30 Years to 100 Years" }, "enrollment_count": 11, "start_date": "2020-12-15", "completion_date": "2024-12-16", "has_results": false, "last_update_posted_date": "2024-12-24", "last_synced_at": "2026-10-01T11:32:39.393Z", "location_count": 2, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT04170062" }, { "nct_id": "NCT02689531", "title": "CTTI Risk Factors for HABP/VABP Study", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Pneumonia, Ventilator-Associated", "Pneumonia, Bacterial", "Pneumonia, Hospital-Acquired" ], "interventions": [], "intervention_types": [], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 7530, "start_date": "2016-02", "completion_date": "2018-02", "has_results": false, "last_update_posted_date": "2023-06-15", "last_synced_at": "2026-10-01T11:32:39.393Z", "location_count": 15, "location_summary": "Birmingham, Alabama • Los Angeles, California • Chicago, Illinois + 12 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Louisville", "state": "Kentucky" }, { "city": "New Orleans", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT02689531" } ] }