{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nutritive+Sweetener&page=2",
    "query": {
      "intervention": "Nutritive Sweetener",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nutritive+Sweetener&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-29T10:51:46.631Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05967741",
      "title": "The Effects of Dietary Erythritol on Platelet Reactivity and Vascular Inflammation",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Platelet Aggregation, Spontaneous",
        "Vascular Thrombosis"
      ],
      "interventions": [
        {
          "name": "Erythritol",
          "type": "OTHER"
        },
        {
          "name": "Aspartame",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 14,
      "start_date": "2023-07-20",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-09-14",
      "last_synced_at": "2026-09-29T10:51:46.631Z",
      "location_count": 1,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05967741"
    },
    {
      "nct_id": "NCT01103921",
      "title": "The Metabolic Effects of Consuming Sugar-Sweetened Beverages for Two Weeks",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Metabolic Syndrome",
        "Insulin Resistance",
        "Dyslipidemia"
      ],
      "interventions": [
        {
          "name": "Glucose",
          "type": "OTHER"
        },
        {
          "name": "Fructose",
          "type": "OTHER"
        },
        {
          "name": "High-Fructose Corn Syrup",
          "type": "OTHER"
        },
        {
          "name": "No sugar (Aspartame)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 214,
      "start_date": "2008-10",
      "completion_date": "2014-01",
      "has_results": false,
      "last_update_posted_date": "2017-05-30",
      "last_synced_at": "2026-09-29T10:51:46.631Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01103921"
    },
    {
      "nct_id": "NCT06842693",
      "title": "Testing Non-nutritive Sweetener Labels in Chile",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diet, Healthy"
      ],
      "interventions": [
        {
          "name": "Control",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Chilean non-nutritive sweetener label",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Colombian non-nutritive sweetener label",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3916,
      "start_date": "2025-07-14",
      "completion_date": "2025-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-09-09",
      "last_synced_at": "2026-09-29T10:51:46.631Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06842693"
    },
    {
      "nct_id": "NCT03579043",
      "title": "The Effects of Beverages on Food Liking",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Nutritive Sweetener",
          "type": "OTHER"
        },
        {
          "name": "Non-Nutritive Sweetener",
          "type": "OTHER"
        },
        {
          "name": "Carbonated Water",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The University of Tennessee, Knoxville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 0,
      "start_date": "2018-05-22",
      "completion_date": "2018-09-30",
      "has_results": false,
      "last_update_posted_date": "2018-11-20",
      "last_synced_at": "2026-09-29T10:51:46.631Z",
      "location_count": 1,
      "location_summary": "Knoxville, Tennessee",
      "locations": [
        {
          "city": "Knoxville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03579043"
    },
    {
      "nct_id": "NCT04567108",
      "title": "Health Effects of Substituting Sugary Beverages With Artificially-sweetened Beverages or Water",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Body Weight"
      ],
      "interventions": [
        {
          "name": "Maintain usual SSBs",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Substitute to non-SSBs",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Study app",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Beverage delivery",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "69 Years",
        "sex": "ALL",
        "summary": "20 Years to 69 Years"
      },
      "enrollment_count": 461,
      "start_date": "2021-04-22",
      "completion_date": "2026-05-21",
      "has_results": false,
      "last_update_posted_date": "2026-07-17",
      "last_synced_at": "2026-09-29T10:51:46.631Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04567108"
    },
    {
      "nct_id": "NCT06933290",
      "title": "Effect of Flavored, Carbonated Drinks on Salivary Flow, Salivary Composition, and Taste Perceptions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Taste Perception",
        "Saliva Production"
      ],
      "interventions": [
        {
          "name": "Beverage",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "PepsiCo Global R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 13,
      "start_date": "2025-03-24",
      "completion_date": "2025-05-22",
      "has_results": false,
      "last_update_posted_date": "2026-06-30",
      "last_synced_at": "2026-09-29T10:51:46.631Z",
      "location_count": 1,
      "location_summary": "Valhalla, New York",
      "locations": [
        {
          "city": "Valhalla",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06933290"
    },
    {
      "nct_id": "NCT01324921",
      "title": "Effect of Nutritional Products on Metabolic Parameters in Subjects With Type 2 Diabetics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 2"
      ],
      "interventions": [
        {
          "name": "No breakfast/beverage only",
          "type": "OTHER"
        },
        {
          "name": "Breakfast",
          "type": "OTHER"
        },
        {
          "name": "10004RF",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Abbott Nutrition",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 37,
      "start_date": "2010-08",
      "completion_date": "2010-09",
      "has_results": false,
      "last_update_posted_date": "2011-03-30",
      "last_synced_at": "2026-09-29T10:51:46.631Z",
      "location_count": 2,
      "location_summary": "Glen Ellyn, Illinois • Cincinnati, Ohio",
      "locations": [
        {
          "city": "Glen Ellyn",
          "state": "Illinois"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01324921"
    },
    {
      "nct_id": "NCT06387316",
      "title": "Cephalic Phase Responses to Nutritive and Non-Nutritive Sweeteners",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pre Diabetes"
      ],
      "interventions": [
        {
          "name": "No Oral Stimulation",
          "type": "OTHER"
        },
        {
          "name": "Oral water stimulation",
          "type": "OTHER"
        },
        {
          "name": "Oral Salt Stimulation",
          "type": "OTHER"
        },
        {
          "name": "Oral Sucralose Stimulation",
          "type": "OTHER"
        },
        {
          "name": "Oral Sucrose stimulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Purdue University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 30,
      "start_date": "2024-03-26",
      "completion_date": "2025-03-30",
      "has_results": false,
      "last_update_posted_date": "2024-04-29",
      "last_synced_at": "2026-09-29T10:51:46.631Z",
      "location_count": 1,
      "location_summary": "West Lafayette, Indiana",
      "locations": [
        {
          "city": "West Lafayette",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06387316"
    },
    {
      "nct_id": "NCT04208256",
      "title": "Food Intake and the Adolescent Brain",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Feeding Behavior",
        "Brain",
        "Adolescent"
      ],
      "interventions": [
        {
          "name": "Energy Stimulus",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "13 Years to 18 Years"
      },
      "enrollment_count": 63,
      "start_date": "2019-12-30",
      "completion_date": "2024-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-06-08",
      "last_synced_at": "2026-09-29T10:51:46.631Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04208256"
    },
    {
      "nct_id": "NCT02018237",
      "title": "High Fructose Corn Syrup",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nonalcoholic Fatty Liver Disease",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "High fructose corn syrup diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard diet (low in high fructose corn syrup)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 47,
      "start_date": "2012-03",
      "completion_date": "2016-03",
      "has_results": false,
      "last_update_posted_date": "2017-03-27",
      "last_synced_at": "2026-09-29T10:51:46.631Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02018237"
    }
  ]
}