{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=OPIOID&page=25",
    "query": {
      "intervention": "OPIOID",
      "page": 25
    },
    "page_size": 10
  },
  "pagination": {
    "page": 25,
    "page_size": 10,
    "total_count": 2682,
    "total_pages": 269,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=OPIOID&page=26&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=OPIOID&page=24&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-26T06:16:05.319Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03655600",
      "title": "Acupressure for Pain and Opioid Use Among Breast Cancer Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer",
        "Fatigue",
        "Chronic Pain"
      ],
      "interventions": [
        {
          "name": "Self-administered acupressure",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 8,
      "start_date": "2018-09-17",
      "completion_date": "2019-10-17",
      "has_results": false,
      "last_update_posted_date": "2019-10-25",
      "last_synced_at": "2026-10-26T06:16:05.319Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03655600"
    },
    {
      "nct_id": "NCT03954964",
      "title": "Increasing Awareness of Opioid Disposal in the Orthopedic Patient Population",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Total Joint Replacement",
        "Hip Total Joint Replacement"
      ],
      "interventions": [
        {
          "name": "Education on disposal of opioids",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2019-06-03",
      "completion_date": "2019-12-31",
      "has_results": false,
      "last_update_posted_date": "2020-03-26",
      "last_synced_at": "2026-10-26T06:16:05.319Z",
      "location_count": 1,
      "location_summary": "Scottsdale, Arizona",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03954964"
    },
    {
      "nct_id": "NCT06709716",
      "title": "Impact of Preoperative Quadratus Lumborum Block on Postoperative Opioid Consumption After Laparoscopic Hysterectomy",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Postoperative Pain",
        "Laparoscopic Hysterectomy",
        "Nerve Block",
        "Quadratus Lumborum Block"
      ],
      "interventions": [
        {
          "name": "Quadratus Lumborum Block (QLB)",
          "type": "DRUG"
        },
        {
          "name": "Quadratus lumborum block",
          "type": "DRUG"
        },
        {
          "name": "Local Anesthetic Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Walter Reed National Military Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 76,
      "start_date": "2024-12-01",
      "completion_date": "2026-02",
      "has_results": false,
      "last_update_posted_date": "2024-11-29",
      "last_synced_at": "2026-10-26T06:16:05.319Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06709716"
    },
    {
      "nct_id": "NCT06731348",
      "title": "Patient Satisfaction With Opioid Restriction After Urogynecologic Surgery",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Patient Satisfaction",
        "Opioid Use After Surgery",
        "Urogynecologic Surgery"
      ],
      "interventions": [
        {
          "name": "restricted opioid prescribing",
          "type": "DRUG"
        },
        {
          "name": "standard opioid prescribing",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Walter Reed National Military Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 92,
      "start_date": "2024-12-01",
      "completion_date": "2026-07-01",
      "has_results": false,
      "last_update_posted_date": "2025-06-11",
      "last_synced_at": "2026-10-26T06:16:05.319Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06731348"
    },
    {
      "nct_id": "NCT05093309",
      "title": "Preventing Opioid Overdose Deaths by Empowering Pharmacists to Dispense Naloxone",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Overdose"
      ],
      "interventions": [
        {
          "name": "Educational Webinar",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Resources",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Reminders",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Auburn University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 55,
      "start_date": "2018-09-18",
      "completion_date": "2019-09-18",
      "has_results": false,
      "last_update_posted_date": "2021-10-26",
      "last_synced_at": "2026-10-26T06:16:05.319Z",
      "location_count": 1,
      "location_summary": "Auburn, Alabama",
      "locations": [
        {
          "city": "Auburn",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05093309"
    },
    {
      "nct_id": "NCT03538652",
      "title": "Just-In-Time Adaptive Interventions for Addictive Behaviors",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Addiction"
      ],
      "interventions": [
        {
          "name": "Formative Interviews (not an intervention)",
          "type": "OTHER"
        },
        {
          "name": "Cognitive-behavioral therapy (CBT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Acceptance and commitment therapy (ACT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "No intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "National Institute on Drug Abuse (NIDA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 9,
      "start_date": "2020-02-19",
      "completion_date": "2020-03-13",
      "has_results": true,
      "last_update_posted_date": "2025-09-09",
      "last_synced_at": "2026-10-26T06:16:05.319Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03538652"
    },
    {
      "nct_id": "NCT04979247",
      "title": "Intravenous Oliceridine and Opioid-related Complications",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Major Surgery"
      ],
      "interventions": [
        {
          "name": "Oliceridine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 204,
      "start_date": "2021-09-15",
      "completion_date": "2024-01-10",
      "has_results": true,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-10-26T06:16:05.319Z",
      "location_count": 3,
      "location_summary": "Winston-Salem, North Carolina • Cleveland, Ohio",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04979247"
    },
    {
      "nct_id": "NCT05256108",
      "title": "Assessment of Abuse Potential of Cebranopadol in Humans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Human Abuse Potential"
      ],
      "interventions": [
        {
          "name": "Oxycodone 40 mg",
          "type": "DRUG"
        },
        {
          "name": "Tramadol 600 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Cebranopadol 600 µg",
          "type": "DRUG"
        },
        {
          "name": "Cebranopadol 1000 µg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tris Pharma, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 38,
      "start_date": "2022-03-28",
      "completion_date": "2022-07-12",
      "has_results": false,
      "last_update_posted_date": "2022-07-27",
      "last_synced_at": "2026-10-26T06:16:05.319Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05256108"
    },
    {
      "nct_id": "NCT05348317",
      "title": "Developing a Telehealth Model to Improve Treatment Access for Rural Veterans With Substance Use Disorders",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Substance Use",
        "Substance Use Disorders",
        "Substance Dependence",
        "Veterans"
      ],
      "interventions": [
        {
          "name": "VetReach",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 25,
      "start_date": "2022-05-19",
      "completion_date": "2027-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-10-13",
      "last_synced_at": "2026-10-26T06:16:05.319Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05348317"
    },
    {
      "nct_id": "NCT02081391",
      "title": "A Study to Look at Tapentadol Oral Solution in Children and Adolescents in Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Acute Pain"
      ],
      "interventions": [
        {
          "name": "Tapentadol oral solution 4 mg/mL",
          "type": "DRUG"
        },
        {
          "name": "Tapentadol oral solution 20 mg/mL",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Grünenthal GmbH",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "1 Day to 18 Years"
      },
      "enrollment_count": 216,
      "start_date": "2015-02-19",
      "completion_date": "2019-03-14",
      "has_results": true,
      "last_update_posted_date": "2020-01-18",
      "last_synced_at": "2026-10-26T06:16:05.319Z",
      "location_count": 13,
      "location_summary": "Little Rock, Arkansas • Stanford, California • Miami, Florida + 9 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02081391"
    }
  ]
}