{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=OPTIMIZE&page=25",
    "query": {
      "intervention": "OPTIMIZE",
      "page": 25
    },
    "page_size": 10
  },
  "pagination": {
    "page": 25,
    "page_size": 10,
    "total_count": 664,
    "total_pages": 67,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=OPTIMIZE&page=26&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=OPTIMIZE&page=24&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-27T15:06:12.917Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05842889",
      "title": "Adaptation and Implementation of Peer Support in Brazil",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Peer Support"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 48,
      "start_date": "2024-08-01",
      "completion_date": "2025-05",
      "has_results": false,
      "last_update_posted_date": "2025-01-13",
      "last_synced_at": "2026-10-27T15:06:12.917Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05842889"
    },
    {
      "nct_id": "NCT04462159",
      "title": "The Young Heart Study",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atherosclerotic Cardiovascular Disease",
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "Risk Reduction Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Northwell Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "59 Years",
        "sex": "ALL",
        "summary": "18 Years to 59 Years"
      },
      "enrollment_count": 60,
      "start_date": "2020-05-27",
      "completion_date": "2026-05-27",
      "has_results": false,
      "last_update_posted_date": "2023-11-01",
      "last_synced_at": "2026-10-27T15:06:12.917Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04462159"
    },
    {
      "nct_id": "NCT02236559",
      "title": "High Flow Therapy for the Treatment of Respiratory Failure in the ED",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "Noninvasive positive pressure ventilation (NIPPV)",
          "type": "DEVICE"
        },
        {
          "name": "Vapotherm",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vapotherm, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 204,
      "start_date": "2014-09",
      "completion_date": "2017-02",
      "has_results": true,
      "last_update_posted_date": "2019-05-23",
      "last_synced_at": "2026-10-27T15:06:12.917Z",
      "location_count": 5,
      "location_summary": "Athens, Georgia • Florence, South Carolina • Chattanooga, Tennessee + 2 more",
      "locations": [
        {
          "city": "Athens",
          "state": "Georgia"
        },
        {
          "city": "Florence",
          "state": "South Carolina"
        },
        {
          "city": "Chattanooga",
          "state": "Tennessee"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "The Woodlands",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02236559"
    },
    {
      "nct_id": "NCT03098277",
      "title": "Movement Tracking Devices to Monitor Physical Activity in Patients Undergoing Chemotherapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Solid Neoplasm"
      ],
      "interventions": [
        {
          "name": "Accelerometer",
          "type": "OTHER"
        },
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        },
        {
          "name": "Physical Activity Measurement",
          "type": "OTHER"
        },
        {
          "name": "Telephone-Based Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 41,
      "start_date": "2016-05-06",
      "completion_date": "2019-02-06",
      "has_results": false,
      "last_update_posted_date": "2025-06-25",
      "last_synced_at": "2026-10-27T15:06:12.917Z",
      "location_count": 3,
      "location_summary": "Los Angeles, California • Newport Beach, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03098277"
    },
    {
      "nct_id": "NCT04060953",
      "title": "Quality of Life in Managing Chronic Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Health-Related Quality of Life Report",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Texas Health Science Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "21 Years to 79 Years"
      },
      "enrollment_count": 102,
      "start_date": "2019-08-16",
      "completion_date": "2020-01-14",
      "has_results": false,
      "last_update_posted_date": "2020-02-26",
      "last_synced_at": "2026-10-27T15:06:12.917Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04060953"
    },
    {
      "nct_id": "NCT05062902",
      "title": "A Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain Management",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Interstitial Cystitis",
        "Chronic Pain",
        "Pelvic Floor; Relaxation",
        "Pelvic Floor Disorders"
      ],
      "interventions": [
        {
          "name": "High Density Surface Electromyographic, precision botulinum neurotoxin injection guidance medical device",
          "type": "DEVICE"
        },
        {
          "name": "Botulinum Neurotoxin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "HillMed Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 60 Years · Female only"
      },
      "enrollment_count": 46,
      "start_date": "2025-09-15",
      "completion_date": "2027-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-08-19",
      "last_synced_at": "2026-10-27T15:06:12.917Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05062902"
    },
    {
      "nct_id": "NCT04576442",
      "title": "Evaluation of the Asthma Management Program to Promote Activity for Students in Schools (Asthma-PASS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Asthma in Children"
      ],
      "interventions": [
        {
          "name": "Asthma-PASS",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Basic Asthma Management (AM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Child/Caregiver Education session",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "4 Years to 12 Years"
      },
      "enrollment_count": 452,
      "start_date": "2021-02-09",
      "completion_date": "2025-08-27",
      "has_results": false,
      "last_update_posted_date": "2026-09-25",
      "last_synced_at": "2026-10-27T15:06:12.917Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04576442"
    },
    {
      "nct_id": "NCT05422573",
      "title": "Clinical Trial of the Sequence of Cardiovascular Genetic Counseling and Testing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Genetic Counseling",
        "Inherited Cardiac Disease"
      ],
      "interventions": [
        {
          "name": "post-test cardiovascular genetic counseling with pre-test education by video",
          "type": "BEHAVIORAL"
        },
        {
          "name": "required phone call with genetic counselor pre-test",
          "type": "BEHAVIORAL"
        },
        {
          "name": "optional phone call with genetic counselor pre-test",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 393,
      "start_date": "2022-12-20",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-09-09",
      "last_synced_at": "2026-10-27T15:06:12.917Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05422573"
    },
    {
      "nct_id": "NCT03492229",
      "title": "Cortical Priming to Optimize Gait Rehabilitation Post Stroke",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke"
      ],
      "interventions": [
        {
          "name": "tDCS",
          "type": "OTHER"
        },
        {
          "name": "AMT",
          "type": "OTHER"
        },
        {
          "name": "Treadmill training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 81,
      "start_date": "2014-01-01",
      "completion_date": "2020-08-15",
      "has_results": false,
      "last_update_posted_date": "2022-08-29",
      "last_synced_at": "2026-10-27T15:06:12.917Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03492229"
    },
    {
      "nct_id": "NCT03242057",
      "title": "Comparison of Primary Extubation Failure Between NIPPV and NI-NAVA",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Preterm Infant",
        "BPD - Bronchopulmonary Dysplasia",
        "Barotrauma"
      ],
      "interventions": [
        {
          "name": "NAVA",
          "type": "OTHER"
        },
        {
          "name": "NIPPV",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "24 Weeks",
        "maximum_age": "32 Weeks",
        "sex": "ALL",
        "summary": "24 Weeks to 32 Weeks"
      },
      "enrollment_count": 30,
      "start_date": "2017-10-23",
      "completion_date": "2019-09-05",
      "has_results": false,
      "last_update_posted_date": "2020-02-19",
      "last_synced_at": "2026-10-27T15:06:12.917Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03242057"
    }
  ]
}