{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=OPTIMIZE&page=9",
    "query": {
      "intervention": "OPTIMIZE",
      "page": 9
    },
    "page_size": 10
  },
  "pagination": {
    "page": 9,
    "page_size": 10,
    "total_count": 664,
    "total_pages": 67,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=OPTIMIZE&page=10&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=OPTIMIZE&page=8&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-24T21:39:42.438Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03541785",
      "title": "Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric AKI",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Kidney Injury",
        "Renal Replacement Therapy",
        "Pediatric Intensive Care Units"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "3 Months to 25 Years"
      },
      "enrollment_count": 420,
      "start_date": "2018-07-01",
      "completion_date": "2029-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-23",
      "last_synced_at": "2026-10-24T21:39:42.438Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03541785"
    },
    {
      "nct_id": "NCT04882449",
      "title": "Surveillance and Alert-based Multiparameter Monitoring to Reduce Worsening Heart Failure Events",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Bodyport Cardiac Scale",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Bodyport Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 329,
      "start_date": "2021-07-08",
      "completion_date": "2023-07-31",
      "has_results": true,
      "last_update_posted_date": "2025-02-10",
      "last_synced_at": "2026-10-24T21:39:42.438Z",
      "location_count": 8,
      "location_summary": "Boynton Beach, Florida • Panama City, Florida • Gainesville, Georgia + 5 more",
      "locations": [
        {
          "city": "Boynton Beach",
          "state": "Florida"
        },
        {
          "city": "Panama City",
          "state": "Florida"
        },
        {
          "city": "Gainesville",
          "state": "Georgia"
        },
        {
          "city": "Kansas City",
          "state": "Kansas"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04882449"
    },
    {
      "nct_id": "NCT06541041",
      "title": "Nerve Transfers Plus Electrical Stimulation to Improve Hand Function in Cervical Spinal Cord Injury",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cervical Spinal Cord Injury",
        "Cervical Spinal Cord Paralysis",
        "Tetraplegia",
        "Tetraplegia/Tetraparesis",
        "Tetraplegic Spinal Paralysis"
      ],
      "interventions": [
        {
          "name": "Brief intraoperative electrical stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Temporary Postoperative Peripheral Nerve Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 10,
      "start_date": "2025-02-10",
      "completion_date": "2028-09",
      "has_results": false,
      "last_update_posted_date": "2025-02-19",
      "last_synced_at": "2026-10-24T21:39:42.438Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06541041"
    },
    {
      "nct_id": "NCT01990222",
      "title": "Leveraging Mobile Health Technology to Optimize Early Stimulant Medication Treatment: A Feasibility Pilot",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Attention Deficit Disorder With Hyperactivity"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "5 Years to 12 Years"
      },
      "enrollment_count": 26,
      "start_date": "2014-01",
      "completion_date": "2018-10",
      "has_results": false,
      "last_update_posted_date": "2020-02-17",
      "last_synced_at": "2026-10-24T21:39:42.438Z",
      "location_count": 3,
      "location_summary": "Los Angeles, California • Northridge, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Northridge",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01990222"
    },
    {
      "nct_id": "NCT04442724",
      "title": "Bladder Fiducial Markers and Multiparametric-MRI (Mp-MRI) to Optimize Bladder Chemo-radiotherapy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bladder Cancer",
        "Urinary Bladder Neoplasm",
        "Urologic Neoplasms",
        "Neoplasms",
        "Urinary Bladder Diseases"
      ],
      "interventions": [
        {
          "name": "Fiducial marker placement",
          "type": "PROCEDURE"
        },
        {
          "name": "Multiparametric MRI (mpMRI)",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2020-07-01",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-08-14",
      "last_synced_at": "2026-10-24T21:39:42.438Z",
      "location_count": 3,
      "location_summary": "Los Angeles, California • Boston, Massachusetts",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04442724"
    },
    {
      "nct_id": "NCT02609880",
      "title": "Cognitive Behavioral Effects on Sleep, Pain, and Cytokines in Gynecologic Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Genital Neoplasms, Female",
        "Insomnia",
        "Pain",
        "Adaptation, Psychological"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Psychoeducation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 90 Years · Female only"
      },
      "enrollment_count": 64,
      "start_date": "2009-07",
      "completion_date": "2023-05-02",
      "has_results": false,
      "last_update_posted_date": "2023-06-15",
      "last_synced_at": "2026-10-24T21:39:42.438Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02609880"
    },
    {
      "nct_id": "NCT00241969",
      "title": "Behavioral & Nutritional Treatment to Help CF Preschoolers Grow",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cystic Fibrosis",
        "Pancreatic Cystic Fibrosis"
      ],
      "interventions": [
        {
          "name": "Behavioral and Nutrition Treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Education and Attention Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "6 Years",
        "sex": "ALL",
        "summary": "2 Years to 6 Years"
      },
      "enrollment_count": 78,
      "start_date": "2006-01",
      "completion_date": "2015-06",
      "has_results": true,
      "last_update_posted_date": "2018-05-22",
      "last_synced_at": "2026-10-24T21:39:42.438Z",
      "location_count": 5,
      "location_summary": "Tucson, Arizona • Ann Arbor, Michigan • Cincinnati, Ohio + 2 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00241969"
    },
    {
      "nct_id": "NCT05235360",
      "title": "Factorial Trial Testing Guided Thinking Tasks to Optimize a Physical Activity Intervention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Physical Inactivity"
      ],
      "interventions": [
        {
          "name": "Episodic future thinking",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Positive affect imagery",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Action planning",
          "type": "BEHAVIORAL"
        },
        {
          "name": "High dose",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Recent thinking",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Neutral imagery",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Low dose",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Southern Methodist University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 184,
      "start_date": "2022-02-14",
      "completion_date": "2025-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-20",
      "last_synced_at": "2026-10-24T21:39:42.438Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05235360"
    },
    {
      "nct_id": "NCT06139523",
      "title": "Optimize Pediatric OCT Imaging",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Retinal Disease",
        "Glaucoma",
        "Optic Nerve Diseases"
      ],
      "interventions": [
        {
          "name": "Investigational contact OCT system",
          "type": "DEVICE"
        },
        {
          "name": "Investigational noncontact OCT system:",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 30,
      "start_date": "2024-01-24",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-08-05",
      "last_synced_at": "2026-10-24T21:39:42.438Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06139523"
    },
    {
      "nct_id": "NCT07507435",
      "title": "Optimizing Medications and Lung Health in People With HIV Through Pharmacist-led Proactive E-Consults",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV",
        "Inhaled Corticosteroid",
        "Proton Pump Inhibitor",
        "Smoking Cessation",
        "Pneumonia"
      ],
      "interventions": [
        {
          "name": "E-consult",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Seattle Institute for Biomedical and Clinical Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 480,
      "start_date": "2026-09",
      "completion_date": "2029-09",
      "has_results": false,
      "last_update_posted_date": "2026-09-16",
      "last_synced_at": "2026-10-24T21:39:42.438Z",
      "location_count": 3,
      "location_summary": "Boise, Idaho • Minneapolis, Minnesota • Seattle, Washington",
      "locations": [
        {
          "city": "Boise",
          "state": "Idaho"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07507435"
    }
  ]
}