{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=OTC+Oral+Rinse+Control",
    "query": {
      "intervention": "OTC Oral Rinse Control"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-16T14:11:09.872Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04409873",
      "title": "Antiseptic Mouthwash / Pre-Procedural Rinse on SARS-CoV-2 Load (COVID-19)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "COVID-19",
        "SARS-CoV 2",
        "Severe Acute Respiratory Syndrome Coronavirus 2",
        "Virus Disease",
        "Coronavirus Infections",
        "Pharyngeal Diseases"
      ],
      "interventions": [
        {
          "name": "Oral-B Mouth Sore mouthwash",
          "type": "DRUG"
        },
        {
          "name": "Crest Pro-Health Multi-Protection mouthwash",
          "type": "DRUG"
        },
        {
          "name": "CloSYS Ultra Sensitive Rinse mouthwash",
          "type": "DRUG"
        },
        {
          "name": "Distilled water",
          "type": "DRUG"
        },
        {
          "name": "Listerine Zero Mouthwash Product",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 54,
      "start_date": "2021-03-31",
      "completion_date": "2022-09-10",
      "has_results": true,
      "last_update_posted_date": "2023-11-18",
      "last_synced_at": "2026-09-16T14:11:09.872Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04409873"
    },
    {
      "nct_id": "NCT02606994",
      "title": "Effect of Over-the-counter Toothpastes on Chemotherapy-induced Oral Mucositis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Mucositis",
        "Neoplasms"
      ],
      "interventions": [
        {
          "name": "Oral Defense Toothpaste",
          "type": "DRUG"
        },
        {
          "name": "Crest Toothpaste",
          "type": "DRUG"
        },
        {
          "name": "Magic Mouth Rinse",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Oral Defense, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2018-05-29",
      "completion_date": "2019-02-04",
      "has_results": false,
      "last_update_posted_date": "2019-02-06",
      "last_synced_at": "2026-09-16T14:11:09.872Z",
      "location_count": 1,
      "location_summary": "Spokane, Washington",
      "locations": [
        {
          "city": "Spokane",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02606994"
    },
    {
      "nct_id": "NCT03154021",
      "title": "Next Science Antimicrobial Mouth Rinse Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Gingivitis",
        "Dental Plaque"
      ],
      "interventions": [
        {
          "name": "Next Science OTC Oral Rinse with Essential Oils",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "OTC Oral Rinse Control",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 118,
      "start_date": "2017-08-28",
      "completion_date": "2018-05-15",
      "has_results": false,
      "last_update_posted_date": "2019-02-18",
      "last_synced_at": "2026-09-16T14:11:09.872Z",
      "location_count": 2,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03154021"
    },
    {
      "nct_id": "NCT01176396",
      "title": "CAMBRA - PBRN Caries Management By Risk Assessment In A Practice-Based Research Network",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Caries prevention active intervention",
          "type": "OTHER"
        },
        {
          "name": "control treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "12 Years to 65 Years"
      },
      "enrollment_count": 460,
      "start_date": "2012-04",
      "completion_date": "2017-05",
      "has_results": false,
      "last_update_posted_date": "2020-04-10",
      "last_synced_at": "2026-09-16T14:11:09.872Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01176396"
    },
    {
      "nct_id": "NCT06660017",
      "title": "Head and Neck Cancer Patients With Oral Mucositis Treated With Ketamine Oral Rinse",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Head and Neck Cancer"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Ketamine Topical",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 62,
      "start_date": "2026-09",
      "completion_date": "2027-11",
      "has_results": false,
      "last_update_posted_date": "2026-08-18",
      "last_synced_at": "2026-09-16T14:11:09.872Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06660017"
    },
    {
      "nct_id": "NCT04620252",
      "title": "Effect of Chewing a Calcium Supplement Before Fluoride Rinse on Salivary Fluoride",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Inactive supplement",
          "type": "DRUG"
        },
        {
          "name": "Tricalcium phosphate supplement",
          "type": "DRUG"
        },
        {
          "name": "Calcium carbonate supplement",
          "type": "DRUG"
        },
        {
          "name": "Calcium citrate supplement",
          "type": "DRUG"
        },
        {
          "name": "Inactive supplement and fluoride mouthwash",
          "type": "DRUG"
        },
        {
          "name": "Calcium carbonate supplement and fluoride mouthwash",
          "type": "DRUG"
        },
        {
          "name": "Calcium citrate supplement and fluoride mouthwash",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 18,
      "start_date": "2021-02-01",
      "completion_date": "2022-03-31",
      "has_results": false,
      "last_update_posted_date": "2022-05-09",
      "last_synced_at": "2026-09-16T14:11:09.872Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04620252"
    }
  ]
}