{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Obesity+pharmacotherapy",
    "query": {
      "intervention": "Obesity pharmacotherapy"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 59,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Obesity+pharmacotherapy&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-01T23:04:09.981Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03418857",
      "title": "Probiotics and Gut Health",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Metabolic Syndrome"
      ],
      "interventions": [
        {
          "name": "Yogurt smoothie with BB-12",
          "type": "DRUG"
        },
        {
          "name": "Yogurt smoothie",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Penn State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "55 Years to 75 Years"
      },
      "enrollment_count": 40,
      "start_date": "2018-06-29",
      "completion_date": "2022-12",
      "has_results": false,
      "last_update_posted_date": "2021-12-14",
      "last_synced_at": "2026-09-01T23:04:09.981Z",
      "location_count": 1,
      "location_summary": "University Park, Pennsylvania",
      "locations": [
        {
          "city": "University Park",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03418857"
    },
    {
      "nct_id": "NCT07736729",
      "title": "Continuous Wearable Biometric Monitoring in Adults Undergoing Obesity Treatment (SMART-BMI)",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Biometric-informed care",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control Arm: Standard Care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Jeff Reeves",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 260,
      "start_date": "2026-08-17",
      "completion_date": "2031-02-28",
      "has_results": false,
      "last_update_posted_date": "2026-07-30",
      "last_synced_at": "2026-09-01T23:04:09.981Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07736729"
    },
    {
      "nct_id": "NCT00532779",
      "title": "A Study of the Safety and Efficacy of Two Doses of Naltrexone SR/Bupropion SR and Placebo in Overweight and Obese Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Obesity",
        "Overweight"
      ],
      "interventions": [
        {
          "name": "Naltrexone SR 16 mg/Bupropion SR 360 mg /day",
          "type": "DRUG"
        },
        {
          "name": "Naltrexone SR 32 mg/Bupropion SR 360 mg /day",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Ancillary therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Orexigen Therapeutics, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 1742,
      "start_date": "2007-10",
      "completion_date": "2009-05",
      "has_results": true,
      "last_update_posted_date": "2014-11-21",
      "last_synced_at": "2026-09-01T23:04:09.981Z",
      "location_count": 34,
      "location_summary": "Birmingham, Alabama • Fairhope, Alabama • Chandler, Arizona + 28 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Fairhope",
          "state": "Alabama"
        },
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00532779"
    },
    {
      "nct_id": "NCT01922934",
      "title": "A Toolbox Approach to Obesity Treatment in Primary Care",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Commercial weight loss program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Colorado Weigh",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Meal replacements",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Obesity pharmacotherapy",
          "type": "DRUG"
        },
        {
          "name": "Recreation center passes",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DIETARY_SUPPLEMENT",
        "DRUG"
      ],
      "sponsor": "Denver Health and Hospital Authority",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 4730,
      "start_date": "2014-01",
      "completion_date": "2016-08",
      "has_results": true,
      "last_update_posted_date": "2017-08-18",
      "last_synced_at": "2026-09-01T23:04:09.981Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01922934"
    },
    {
      "nct_id": "NCT07021937",
      "title": "Brain Plasticity and GLP-1 Receptor Agonist Treatment for Obesity",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Obesity/Therapy"
      ],
      "interventions": [
        {
          "name": "Semaglutide 1.7mg subcutaneous",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "12 Years to 45 Years"
      },
      "enrollment_count": 120,
      "start_date": "2026-06-15",
      "completion_date": "2031-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-02",
      "last_synced_at": "2026-09-01T23:04:09.981Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07021937"
    },
    {
      "nct_id": "NCT06948058",
      "title": "Clinical Research Evaluating Smoking Cessation With E-Cigarettes and Nicotine Therapy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Cessation",
        "Obesity and Obesity-related Medical Conditions"
      ],
      "interventions": [
        {
          "name": "Electronic Cigarettes (EC)",
          "type": "OTHER"
        },
        {
          "name": "Nicotine replacement therapy (NRT)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2025-04-01",
      "completion_date": "2027-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-18",
      "last_synced_at": "2026-09-01T23:04:09.981Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06948058"
    },
    {
      "nct_id": "NCT02496611",
      "title": "Enhancing Weight Loss Maintenance With GLP-1RA (BYDUREON™) in Adolescents With Severe Obesity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Severe Obesity"
      ],
      "interventions": [
        {
          "name": "Weight loss with pharmacotherapy",
          "type": "DRUG"
        },
        {
          "name": "Weight loss without pharmacotherapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "12 Years to 17 Years"
      },
      "enrollment_count": 100,
      "start_date": "2015-12",
      "completion_date": "2020-08-14",
      "has_results": true,
      "last_update_posted_date": "2022-01-03",
      "last_synced_at": "2026-09-01T23:04:09.981Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02496611"
    },
    {
      "nct_id": "NCT04291950",
      "title": "Epigenetics of TNBC in Overweight and Obese Hispanic & Non-Hispanic White Women",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Triple Negative Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Needle core biopsy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Arizona",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2022-08-30",
      "completion_date": "2025-08-30",
      "has_results": false,
      "last_update_posted_date": "2022-12-20",
      "last_synced_at": "2026-09-01T23:04:09.981Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04291950"
    },
    {
      "nct_id": "NCT02029989",
      "title": "Point-of-Care Testing (POCT) Detection and Management of Metabolic Syndrome in Patients With Mental Illness",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hyperlipidemia",
        "Diabetes",
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Glucose and lipids",
          "type": "DEVICE"
        },
        {
          "name": "Glycosylated Hemoglobin A1c",
          "type": "DEVICE"
        },
        {
          "name": "Blood Pressure and Heart Rate",
          "type": "DEVICE"
        },
        {
          "name": "Body mass index",
          "type": "DEVICE"
        },
        {
          "name": "Waist and Hip circumference",
          "type": "DEVICE"
        },
        {
          "name": "Comprehensive Medication Management",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 121,
      "start_date": "2010-02",
      "completion_date": "2012-02",
      "has_results": true,
      "last_update_posted_date": "2024-04-04",
      "last_synced_at": "2026-09-01T23:04:09.981Z",
      "location_count": 1,
      "location_summary": "Duluth, Minnesota",
      "locations": [
        {
          "city": "Duluth",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02029989"
    },
    {
      "nct_id": "NCT05834062",
      "title": "Phentermine/Topiramate as Preventive Pharmacotherapy for Obesity",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Obesity, Adolescent"
      ],
      "interventions": [
        {
          "name": "Qsymia and lifestyle management therapy",
          "type": "DRUG"
        },
        {
          "name": "Placebo and lifestyle management therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "22 Years",
        "sex": "ALL",
        "summary": "16 Years to 22 Years"
      },
      "enrollment_count": 0,
      "start_date": "2023-10-17",
      "completion_date": "2027-08",
      "has_results": false,
      "last_update_posted_date": "2023-10-26",
      "last_synced_at": "2026-09-01T23:04:09.981Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05834062"
    }
  ]
}