{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Observational+Protocol&page=6",
    "query": {
      "intervention": "Observational Protocol",
      "page": 6
    },
    "page_size": 10
  },
  "pagination": {
    "page": 6,
    "page_size": 10,
    "total_count": 258,
    "total_pages": 26,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Observational+Protocol&page=7&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Observational+Protocol&page=5&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-31T21:27:21.500Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00698139",
      "title": "Cardiovascular and Neurohormonal Effects of Faster Atrial Pacing Rate",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Medtronic Pacemaker",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 3,
      "start_date": "2011-04",
      "completion_date": "2012-09",
      "has_results": true,
      "last_update_posted_date": "2018-04-27",
      "last_synced_at": "2026-10-31T21:27:21.500Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00698139"
    },
    {
      "nct_id": "NCT05026645",
      "title": "The Medical Management in Patients Exposed to Weapons of Mass Destruction",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chemical Injury",
        "Chemicals; Intoxication",
        "Acute Respiratory Distress Syndrome",
        "Distress Respiratory Syndrome",
        "Medical Emergencies"
      ],
      "interventions": [
        {
          "name": "Clinical interventions performed in acute settings (contaminated environment)",
          "type": "PROCEDURE"
        },
        {
          "name": "Protection (clinician and patient)",
          "type": "PROCEDURE"
        },
        {
          "name": "Decontamination (clinician and patient)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "St. Justine's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1000,
      "start_date": "2020-10-01",
      "completion_date": "2036-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-10-01",
      "last_synced_at": "2026-10-31T21:27:21.500Z",
      "location_count": 1,
      "location_summary": "College Park, Maryland",
      "locations": [
        {
          "city": "College Park",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05026645"
    },
    {
      "nct_id": "NCT02449980",
      "title": "Primary Versus Delayed Surgical Therapy for Pediatric Spontaneous Pneumothorax",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pneumothorax"
      ],
      "interventions": [
        {
          "name": "Primary Surgery Group",
          "type": "PROCEDURE"
        },
        {
          "name": "Initial Non-operative management",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "5 Years to 18 Years"
      },
      "enrollment_count": 3,
      "start_date": "2017-05-05",
      "completion_date": "2019-01-31",
      "has_results": false,
      "last_update_posted_date": "2019-11-06",
      "last_synced_at": "2026-10-31T21:27:21.500Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02449980"
    },
    {
      "nct_id": "NCT01867905",
      "title": "Antibiotic Administration and Blood Culture Positivity in Severe Sepsis and Septic Shock",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Severe Sepsis",
        "Septic Shock",
        "Bacteremia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of British Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 330,
      "start_date": "2014-03-01",
      "completion_date": "2019-04-10",
      "has_results": false,
      "last_update_posted_date": "2019-04-16",
      "last_synced_at": "2026-10-31T21:27:21.500Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01867905"
    },
    {
      "nct_id": "NCT03250832",
      "title": "Study of TSR-033 With an Anti-programmed Cell Death-1 Receptor (PD-1) in Participants With Advanced Solid Tumors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Neoplasms"
      ],
      "interventions": [
        {
          "name": "TSR-033",
          "type": "DRUG"
        },
        {
          "name": "Dostarlimab",
          "type": "DRUG"
        },
        {
          "name": "mFOLFOX6",
          "type": "DRUG"
        },
        {
          "name": "FOLFIRI",
          "type": "DRUG"
        },
        {
          "name": "Bevacizumab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tesaro, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 111,
      "start_date": "2017-08-08",
      "completion_date": "2023-02-13",
      "has_results": true,
      "last_update_posted_date": "2024-04-11",
      "last_synced_at": "2026-10-31T21:27:21.500Z",
      "location_count": 11,
      "location_summary": "Los Angeles, California • Whittier, California • Sarasota, Florida + 8 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Whittier",
          "state": "California"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03250832"
    },
    {
      "nct_id": "NCT02233309",
      "title": "A Prospective Observational Study of Epidural Pressures During Caudal Epidural in the Pediatric Population",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Anesthesia, Caudal"
      ],
      "interventions": [
        {
          "name": "Monitoring of pressures during caudal anesthesia",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Jessica Goeller",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 36,
      "start_date": "2014-04",
      "completion_date": "2014-09",
      "has_results": true,
      "last_update_posted_date": "2015-05-28",
      "last_synced_at": "2026-10-31T21:27:21.500Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02233309"
    },
    {
      "nct_id": "NCT01306994",
      "title": "Study of Resting and Exercising Body Functioning in Freeman-Sheldon Syndrome and Related Conditions",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Arthrogryposis",
        "Craniofacial Abnormalities"
      ],
      "interventions": [
        {
          "name": "Lactate, Glucose, and Adenosine Triphosphate Blood Levels",
          "type": "OTHER"
        },
        {
          "name": "Physiological Stress Test",
          "type": "PROCEDURE"
        },
        {
          "name": "Functional Enquiry Form",
          "type": "OTHER"
        },
        {
          "name": "Strength, Joint ROM, Girth and Length Measurements",
          "type": "OTHER"
        },
        {
          "name": "Study Physical Examination",
          "type": "OTHER"
        },
        {
          "name": "Observational Gait Analysis",
          "type": "OTHER"
        },
        {
          "name": "Mental Health Interview",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Freeman-Sheldon Research Group, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 0,
      "start_date": "2014-03",
      "completion_date": "2022-06",
      "has_results": false,
      "last_update_posted_date": "2022-06-06",
      "last_synced_at": "2026-10-31T21:27:21.500Z",
      "location_count": 1,
      "location_summary": "Buckhannon, West Virginia",
      "locations": [
        {
          "city": "Buckhannon",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01306994"
    },
    {
      "nct_id": "NCT00869245",
      "title": "Efficacy Evaluation of Observation Unit Cardiac Magnetic Resonance Imaging (MRI) in Patients With Intermediate Risk Acute Chest Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Coronary Syndrome",
        "Chest Pain"
      ],
      "interventions": [
        {
          "name": "OU - Cardiac MRI",
          "type": "OTHER"
        },
        {
          "name": "OU - Conventional Care Testing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 124,
      "start_date": "2009-03",
      "completion_date": "2011-10",
      "has_results": false,
      "last_update_posted_date": "2017-11-08",
      "last_synced_at": "2026-10-31T21:27:21.500Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00869245"
    },
    {
      "nct_id": "NCT03127722",
      "title": "Study to Assess Outcomes in Women Undergoing Either Hysteroscopic Sterilization (Essure®) or Laparoscopic Tubal Sterilization",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Contraception"
      ],
      "interventions": [
        {
          "name": "Blood draw",
          "type": "PROCEDURE"
        },
        {
          "name": "ESSURE (BAY1454032)",
          "type": "DEVICE"
        },
        {
          "name": "Laparoscopic tubal sterilization",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Bayer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "21 Years and older · Female only"
      },
      "enrollment_count": 990,
      "start_date": "2017-05-03",
      "completion_date": "2024-12-31",
      "has_results": true,
      "last_update_posted_date": "2026-05-22",
      "last_synced_at": "2026-10-31T21:27:21.500Z",
      "location_count": 57,
      "location_summary": "Chandler, Arizona • Phoenix, Arizona • Tucson, Arizona + 47 more",
      "locations": [
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03127722"
    },
    {
      "nct_id": "NCT00179478",
      "title": "Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Multiple Sclerosis",
        "Optic Neuritis",
        "Transverse Myelitis",
        "Acute Brainstem/Cerebellar Syndrome"
      ],
      "interventions": [
        {
          "name": "interferon beta 1a 30 ug IM once weekly",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 155,
      "start_date": "2001-02",
      "completion_date": "2009-03",
      "has_results": true,
      "last_update_posted_date": "2017-09-06",
      "last_synced_at": "2026-10-31T21:27:21.500Z",
      "location_count": 20,
      "location_summary": "Derby, Connecticut • Tampa, Florida • Atlanta, Georgia + 16 more",
      "locations": [
        {
          "city": "Derby",
          "state": "Connecticut"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Elk Grove",
          "state": "Illinois"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00179478"
    }
  ]
}