{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Ocular+Surface+Disease+Index",
    "query": {
      "intervention": "Ocular Surface Disease Index"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 9,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-27T15:28:34.958Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02761707",
      "title": "Biomarkers in Neural Disorders",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Parkinson's Disease",
        "Alzheimer's Disease",
        "Progressive Supranuclear Palsy",
        "Essential Tremor",
        "Multiple System Atrophy",
        "Drug Induced Parkinson's Disease",
        "Diffuse Lewy Body Disease",
        "Myasthenia Gravis",
        "Spinal Cord Injuries"
      ],
      "interventions": [
        {
          "name": "Electrical Brainstem Responses",
          "type": "OTHER"
        },
        {
          "name": "Olfactory Tests",
          "type": "OTHER"
        },
        {
          "name": "Visual Deprivation",
          "type": "OTHER"
        },
        {
          "name": "Peripheral Nerve Stimulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 54,
      "start_date": "2016-06",
      "completion_date": "2019-07-16",
      "has_results": false,
      "last_update_posted_date": "2019-07-18",
      "last_synced_at": "2026-09-27T15:28:34.958Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02761707"
    },
    {
      "nct_id": "NCT04493658",
      "title": "Differential Diagnosis of Sjögren's Versus Non-Sjögren's Dry Eye",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Keratoconjunctivitis Sicca",
        "Dry Eye Syndromes",
        "Ocular Surface Disease",
        "Sjogren's Syndrome"
      ],
      "interventions": [
        {
          "name": "Questionnaires",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Tear fluid sampling",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Impression Cytology",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 92,
      "start_date": "2021-01-11",
      "completion_date": "2022-10-03",
      "has_results": false,
      "last_update_posted_date": "2023-01-05",
      "last_synced_at": "2026-09-27T15:28:34.958Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04493658"
    },
    {
      "nct_id": "NCT05966532",
      "title": "Emotional Cognition: Establishing Constructs and Neural-Behavioral Mechanisms in Older Adults With Depression",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Major Depressive Disorder (MDD)",
        "Healthy Adult Volunteer"
      ],
      "interventions": [
        {
          "name": "Hot Cognitive Task",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cold cognitive tasks",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Structural magnetic resonance imaging (sMRI)",
          "type": "OTHER"
        },
        {
          "name": "Magnetoencephalography imaging (MEG)",
          "type": "OTHER"
        },
        {
          "name": "four self-report forms per the requirement of the NIH Common Data Elements project",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Four self-report measures to assess interpersonal functioning",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Clinical assessments",
          "type": "BEHAVIORAL"
        },
        {
          "name": "ATHF",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 276,
      "start_date": "2023-12-11",
      "completion_date": "2027-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-30",
      "last_synced_at": "2026-09-27T15:28:34.958Z",
      "location_count": 2,
      "location_summary": "Arlington, Texas • Dallas, Texas",
      "locations": [
        {
          "city": "Arlington",
          "state": "Texas"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05966532"
    },
    {
      "nct_id": "NCT07268599",
      "title": "Moderate-to-Severe Dry Eye Disease Relief Using Acoltremon",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dry Eye Disease (DED)"
      ],
      "interventions": [
        {
          "name": "Acoltremon",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Colvard Kandavel Eye Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 50,
      "start_date": "2025-11-24",
      "completion_date": "2026-10",
      "has_results": false,
      "last_update_posted_date": "2025-12-08",
      "last_synced_at": "2026-09-27T15:28:34.958Z",
      "location_count": 1,
      "location_summary": "Encino, California",
      "locations": [
        {
          "city": "Encino",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07268599"
    },
    {
      "nct_id": "NCT02042820",
      "title": "Ocular Surface Immune Response in Dry Eye Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dry Eye Disease"
      ],
      "interventions": [
        {
          "name": "In vivo confocal microscopy (IVCM)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Tufts Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 67,
      "start_date": "2014-01",
      "completion_date": "2015-07",
      "has_results": false,
      "last_update_posted_date": "2017-10-18",
      "last_synced_at": "2026-09-27T15:28:34.958Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02042820"
    },
    {
      "nct_id": "NCT03560609",
      "title": "Optic Nerve Head Structural Response to IOP Elevation in Patients With Keratoconus",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Keratoconus",
        "Glaucoma"
      ],
      "interventions": [
        {
          "name": "Ophthalmodynamometer",
          "type": "DEVICE"
        },
        {
          "name": "Goldmann applanation tonometer",
          "type": "DEVICE"
        },
        {
          "name": "Pentacam",
          "type": "DEVICE"
        },
        {
          "name": "ORA",
          "type": "DEVICE"
        },
        {
          "name": "Optical Coherence Tomography (OCT)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 3,
      "start_date": "2018-11-15",
      "completion_date": "2024-01-19",
      "has_results": true,
      "last_update_posted_date": "2025-01-29",
      "last_synced_at": "2026-09-27T15:28:34.958Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03560609"
    },
    {
      "nct_id": "NCT03396809",
      "title": "Punctal Plugs and Iodine Related Discomfort",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dry Eye Syndromes"
      ],
      "interventions": [
        {
          "name": "Punctal plug",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of New Mexico",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2017-07-26",
      "completion_date": "2018-12-07",
      "has_results": false,
      "last_update_posted_date": "2024-03-13",
      "last_synced_at": "2026-09-27T15:28:34.958Z",
      "location_count": 1,
      "location_summary": "Albuquerque, New Mexico",
      "locations": [
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03396809"
    },
    {
      "nct_id": "NCT07510087",
      "title": "Glaucoma Related Quality of Life",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Glaucoma"
      ],
      "interventions": [
        {
          "name": "GQL-15",
          "type": "OTHER"
        },
        {
          "name": "Glaucoma Symptom Scale",
          "type": "OTHER"
        },
        {
          "name": "NEI Vision Function Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Ocular Surface Disease Index",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Marc Toeteberg-Harms",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5000,
      "start_date": "2024-12-30",
      "completion_date": "2027-05-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-06",
      "last_synced_at": "2026-09-27T15:28:34.958Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07510087"
    },
    {
      "nct_id": "NCT05615805",
      "title": "The Effect of Ocular Rinse Volume on Surface Irritation After Intravitreal Injections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intravitreal Injection",
        "Ocular Rinse",
        "Age-Related Macular Degeneration",
        "Diabetic Macular Edema",
        "Cystoid Macular Edema"
      ],
      "interventions": [
        {
          "name": "OSDI questionnaire",
          "type": "OTHER"
        },
        {
          "name": "SPEEDII questionnaire",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 142,
      "start_date": "2021-03-01",
      "completion_date": "2021-10-01",
      "has_results": false,
      "last_update_posted_date": "2023-04-25",
      "last_synced_at": "2026-09-27T15:28:34.958Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05615805"
    }
  ]
}