{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Open+Surgery&page=10", "query": { "intervention": "Open Surgery", "page": 10 }, "page_size": 10 }, "pagination": { "page": 10, "page_size": 10, "total_count": 1549, "total_pages": 155, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Open+Surgery&page=11&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Open+Surgery&page=9&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-26T21:35:19.921Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06355791", "title": "Post-Market Clinical Study of Functional Motion Outcomes in Subjects Treated With the Minuteman Device", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Degenerative Conditions of the Lumbar Spine", "Lumbar Spinal Stenosis", "Spondylolisthesis" ], "interventions": [ { "name": "Minuteman G5 Device", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Spinal Simplicity LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 150, "start_date": "2024-05-29", "completion_date": "2030-12", "has_results": false, "last_update_posted_date": "2025-10-03", "last_synced_at": "2026-10-26T21:35:19.921Z", "location_count": 6, "location_summary": "Newnan, Georgia • Indianapolis, Indiana • Kansas City, Kansas + 3 more", "locations": [ { "city": "Newnan", "state": "Georgia" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Kansas City", "state": "Kansas" }, { "city": "Edina", "state": "Minnesota" }, { "city": "Eugene", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT06355791" }, { "nct_id": "NCT07071350", "title": "Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Autonomic Nervous System Disease", "Concussive Injury", "Mild Traumatic Brain Injury", "Post Traumatic Stress Disorder", "Persistent Post Concussion Syndrome" ], "interventions": [ { "name": "HRV Coherence Ratio", "type": "OTHER" }, { "name": "NSI", "type": "BEHAVIORAL" }, { "name": "Pittsburgh Sleep Quality Index (PSQI)", "type": "BEHAVIORAL" }, { "name": "Quantitative Sleep Measures", "type": "BEHAVIORAL" }, { "name": "Patient Global Impression of Change (PGIC)", "type": "BEHAVIORAL" }, { "name": "Cognitive Performance/NIH Toolbox Cognitive Battery", "type": "BEHAVIORAL" }, { "name": "Pain Interference/TBI-QoL Pain Interference Short-Form", "type": "OTHER" }, { "name": "Patient Health Questionnaire-9 (PHQ-9)", "type": "BEHAVIORAL" }, { "name": "PTSD Checklist for DSM-5 (PCL-5)", "type": "BEHAVIORAL" }, { "name": "HRV Biofeedback (HRV-B)", "type": "OTHER" }, { "name": "Psychoeducational (Edu) Comparator Intervention", "type": "OTHER" } ], "intervention_types": [ "OTHER", "BEHAVIORAL" ], "sponsor": "Virginia Commonwealth University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 148, "start_date": "2025-09-02", "completion_date": "2028-09", "has_results": false, "last_update_posted_date": "2026-09-22", "last_synced_at": "2026-10-26T21:35:19.921Z", "location_count": 1, "location_summary": "Richmond, Virginia", "locations": [ { "city": "Richmond", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT07071350" }, { "nct_id": "NCT03343197", "title": "Study of AG-120 and AG-881 in Subjects With Low Grade Glioma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Glioma" ], "interventions": [ { "name": "AG-120", "type": "DRUG" }, { "name": "AG881", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Institut de Recherches Internationales Servier", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 49, "start_date": "2018-03-20", "completion_date": "2025-03-28", "has_results": false, "last_update_posted_date": "2026-02-17", "last_synced_at": "2026-10-26T21:35:19.921Z", "location_count": 6, "location_summary": "Los Angeles, California • San Francisco, California • Boston, Massachusetts + 3 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "New York", "state": "New York" }, { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03343197" }, { "nct_id": "NCT04014075", "title": "DS-8201a in HER2-positive Gastric Cancer That Cannot Be Surgically Removed or Has Spread (DESTINY-Gastric02)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Adenocarcinoma Gastric Stage IV With Metastases", "Adenocarcinoma - GEJ" ], "interventions": [ { "name": "Trastuzumab deruxtecan", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 79, "start_date": "2019-11-26", "completion_date": "2024-02-13", "has_results": true, "last_update_posted_date": "2025-04-03", "last_synced_at": "2026-10-26T21:35:19.921Z", "location_count": 20, "location_summary": "Duarte, California • Los Angeles, California • Monterey, California + 15 more", "locations": [ { "city": "Duarte", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Monterey", "state": "California" }, { "city": "Santa Monica", "state": "California" }, { "city": "Hartford", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT04014075" }, { "nct_id": "NCT03231228", "title": "Safety of 1 g and 2 g of Cefazolin in Pediatric Subjects", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Postoperative Infection" ], "interventions": [ { "name": "Cefazolin 1 g Infusion", "type": "DRUG" }, { "name": "Cefazolin 2 g Infusion", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "B. Braun Medical Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "10 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "10 Years to 17 Years" }, "enrollment_count": 61, "start_date": "2017-11-20", "completion_date": "2019-07-31", "has_results": true, "last_update_posted_date": "2020-07-13", "last_synced_at": "2026-10-26T21:35:19.921Z", "location_count": 5, "location_summary": "Little Rock, Arkansas • Columbia, Missouri • Dallas, Texas + 2 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Columbia", "state": "Missouri" }, { "city": "Dallas", "state": "Texas" }, { "city": "Houston", "state": "Texas" }, { "city": "Roanoke", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT03231228" }, { "nct_id": "NCT03861065", "title": "Secondary Versus Tertiary Wound Closure in High Risk Gynecologic Abdominal Surgical Incisions", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Surgical Incision" ], "interventions": [ { "name": "Tertiary Wound Closure", "type": "PROCEDURE" }, { "name": "Historical Wound Closure", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Wake Forest University Health Sciences", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "FEMALE", "summary": "18 Years to 65 Years · Female only" }, "enrollment_count": 8, "start_date": "2019-02-27", "completion_date": "2020-11-26", "has_results": true, "last_update_posted_date": "2026-04-17", "last_synced_at": "2026-10-26T21:35:19.921Z", "location_count": 1, "location_summary": "Winston-Salem, North Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03861065" }, { "nct_id": "NCT05589896", "title": "A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Acute Leukemia", "Acute Lymphoblastic Leukemia", "Acute Myeloid Leukemia", "Acute Biphenotypic Leukemia", "Acute Undifferentiated Leukemia", "CLL (Chronic Lymphocytic Leukemia)", "Chronic Myeloid Leukemia (CML)", "MDS (Myelodysplastic Syndrome)", "Non-Hodgkin Lymphomas", "Hodgkins Lymphoma", "Cutaneous T Cell Lymphomas (CTCL)" ], "interventions": [ { "name": "Ossium HPC Marrow, Bone Marrow Transplant", "type": "OTHER" }, { "name": "Pre-transplant conditioning - Myeloablative (MAC)", "type": "OTHER" }, { "name": "Pre-transplant conditioning - Reduced Intensity (RIC)", "type": "OTHER" }, { "name": "Post-transplant treatment", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Ossium Health, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 12, "start_date": "2024-08-16", "completion_date": "2029-05-31", "has_results": false, "last_update_posted_date": "2026-09-10", "last_synced_at": "2026-10-26T21:35:19.921Z", "location_count": 9, "location_summary": "Duarte, California • Tampa, Florida • Atlanta, Georgia + 6 more", "locations": [ { "city": "Duarte", "state": "California" }, { "city": "Tampa", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT05589896" }, { "nct_id": "NCT00863603", "title": "The Effect of Oxygen on Healing an Artery From the \"Injury\" of Surgery", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "End Stage Renal Disease" ], "interventions": [ { "name": "oxygen", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 46, "start_date": "2005-01", "completion_date": "2009-08", "has_results": false, "last_update_posted_date": "2012-05-25", "last_synced_at": "2026-10-26T21:35:19.921Z", "location_count": 3, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" }, { "city": "Minneapolis", "state": "Minnesota" }, { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00863603" }, { "nct_id": "NCT01696188", "title": "A Study Comparing Two Methods of Placing an Interscalene Nerve Catheter for Postoperative Pain Control in Patients Who Undergo Open Shoulder Surgery.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Shoulder Pain" ], "interventions": [ { "name": "interscalene nerve catheter", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Thomas Jefferson University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 84, "start_date": "2012-07", "completion_date": "2014-06", "has_results": true, "last_update_posted_date": "2015-11-16", "last_synced_at": "2026-10-26T21:35:19.921Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01696188" }, { "nct_id": "NCT03745794", "title": "Repeat Quadratus Lumborum Block to Reduce Opioid Need in Patients After Pancreatic Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pancreatic Carcinoma" ], "interventions": [ { "name": "Best Practice", "type": "OTHER" }, { "name": "Quadratus Lumborum Block", "type": "DRUG" }, { "name": "Quality-of-Life Assessment", "type": "OTHER" }, { "name": "Questionnaire Administration", "type": "OTHER" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 136, "start_date": "2019-02-28", "completion_date": "2025-07-31", "has_results": true, "last_update_posted_date": "2025-12-23", "last_synced_at": "2026-10-26T21:35:19.921Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03745794" } ] }