{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Operative&page=20", "query": { "intervention": "Operative", "page": 20 }, "page_size": 10 }, "pagination": { "page": 20, "page_size": 10, "total_count": 8313, "total_pages": 832, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Operative&page=21&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Operative&page=19&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-22T02:30:00.640Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06258525", "title": "SAMe in Prevention of Oxaliplatin-associated Liver Injury", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Colorectal Cancer", "Liver Metastases", "Liver Metastasis Colon Cancer", "Liver Injury", "Sinusoidal Obstruction Syndrome", "5-Fluorouracil Toxicity", "Liver Toxicity, Chemically-Induced" ], "interventions": [ { "name": "Standard of care oxaliplatin-based chemotherapy", "type": "RADIATION" }, { "name": "S-adenosylmethionine (SAMe) supplement", "type": "DIETARY_SUPPLEMENT" }, { "name": "Surgery", "type": "PROCEDURE" } ], "intervention_types": [ "RADIATION", "DIETARY_SUPPLEMENT", "PROCEDURE" ], "sponsor": "Cedars-Sinai Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": "2026-10", "completion_date": "2028-10", "has_results": false, "last_update_posted_date": "2026-09-30", "last_synced_at": "2026-10-22T02:30:00.640Z", "location_count": 2, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06258525" }, { "nct_id": "NCT05617716", "title": "Spine Radiosurgery for Symptomatic Metastatic Neoplasms", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Metastatic Neoplasm to the Spine", "Metastatic Neoplasm" ], "interventions": [ { "name": "Conventional external beam radiation therapy dose (EBRT)", "type": "RADIATION" }, { "name": "Spine radiosurgery/stereotactic body radiation therapy standard dose", "type": "RADIATION" }, { "name": "Spine radiosurgery/stereotactic body radiation therapy high dose", "type": "RADIATION" } ], "intervention_types": [ "RADIATION" ], "sponsor": "University of Oklahoma", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 240, "start_date": "2025-09-09", "completion_date": "2029-09-30", "has_results": false, "last_update_posted_date": "2025-10-20", "last_synced_at": "2026-10-22T02:30:00.640Z", "location_count": 2, "location_summary": "Baltimore, Maryland • Oklahoma City, Oklahoma", "locations": [ { "city": "Baltimore", "state": "Maryland" }, { "city": "Oklahoma City", "state": "Oklahoma" } ], "official_url": "https://clinicaltrials.gov/study/NCT05617716" }, { "nct_id": "NCT01035008", "title": "Confocal Endomicroscopy of Pancreatic InVivo", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Pancreatic Cysts" ], "interventions": [ { "name": "Endoscopic Ultrasound (EUS)", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2009-12", "completion_date": "2011-11", "has_results": false, "last_update_posted_date": "2012-10-23", "last_synced_at": "2026-10-22T02:30:00.640Z", "location_count": 1, "location_summary": "Jacksonville, Florida", "locations": [ { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01035008" }, { "nct_id": "NCT06342440", "title": "Early Detection of Advanced Adenomas and Colorectal Cancer", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Colorectal Cancer", "Colorectal Neoplasms", "Colorectal Polyp", "Colorectal Adenocarcinoma", "Colorectal Disorders", "Colorectal Dysplasia", "Colorectal Cancer Stage I", "Colorectal Cancer Stage II", "Colorectal Cancer Stage III", "Colorectal Cancer Stage IV", "Colorectal Neoplasms Malignant", "Colorectal Serrated Adenocarcinoma", "Colorectal Adenoma With Severe Dysplasia", "Colorectal Adenoma With Mild Dysplasia", "Colorectal Adenoma With Moderate Dysplasia", "Colorectal Adenoma and Carcinoma 1", "Colorectal Adenomatous Polyp", "Colorectal Adenocarcinoma Metastatic in the Liver" ], "interventions": [ { "name": "DENEB", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "City of Hope Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 2000, "start_date": "2020-03-15", "completion_date": "2028-06-18", "has_results": false, "last_update_posted_date": "2026-07-07", "last_synced_at": "2026-10-22T02:30:00.640Z", "location_count": 2, "location_summary": "Monrovia, California • San Diego, California", "locations": [ { "city": "Monrovia", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06342440" }, { "nct_id": "NCT01996826", "title": "A Multi-Center Study of the Safety and Efficacy of Bevacizumab in High-Risk Corneal Transplant Survival", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Corneal Neovascularization", "Corneal Graft Failure" ], "interventions": [ { "name": "Avastin® (bevacizumab)", "type": "DRUG" }, { "name": "0.9% NaCl & Refresh Liquigel", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Reza Dana, MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 75, "start_date": "2014-04", "completion_date": "2019-04", "has_results": true, "last_update_posted_date": "2020-08-10", "last_synced_at": "2026-10-22T02:30:00.640Z", "location_count": 3, "location_summary": "Miami, Florida • Boston, Massachusetts • New York, New York", "locations": [ { "city": "Miami", "state": "Florida" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01996826" }, { "nct_id": "NCT01866943", "title": "Role of Topical Tranexamic Acid in Total Hip Arthroplasty", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Post Operative Blood Loss" ], "interventions": [ { "name": "Tranexamic Acid", "type": "DRUG" }, { "name": "Normal Saline Solution", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Northwell Health", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 41, "start_date": "2011-11", "completion_date": "2016-10", "has_results": true, "last_update_posted_date": "2018-03-13", "last_synced_at": "2026-10-22T02:30:00.640Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01866943" }, { "nct_id": "NCT03762889", "title": "Peri-operative Application of Eyeprotx General Anesthesia Goggles As Prevention Against Corneal Injury Post Intubation.", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Corneal Injuries" ], "interventions": [ { "name": "Eyeprotx™ General Anesthesia Protective Goggles", "type": "DEVICE" }, { "name": "Eyelid Tape", "type": "DEVICE" }, { "name": "Eye Ointment", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of Miami", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2019-06", "completion_date": "2019-12", "has_results": false, "last_update_posted_date": "2019-06-06", "last_synced_at": "2026-10-22T02:30:00.640Z", "location_count": 1, "location_summary": "Miami, Florida", "locations": [ { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03762889" }, { "nct_id": "NCT03314974", "title": "Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Acute Leukemia", "Acute Myeloid Leukemia", "Acute Lymphoblastic Leukemia", "Lymphoma", "Chronic Myelogenous Leukemia", "Plasma Cell Leukemia", "Myeloproliferative Neoplasms", "Myelofibrosis", "Myelodysplasia", "Refractory Anemia", "High Risk Anemia", "Chronic Lymphocytic Leukemia", "Small Lymphocytic Lymphoma", "Marginal Zone B-Cell Lymphoma", "Follicular Lymphoma", "Lymphoplasmacytic Lymphoma", "Mantle-Cell Lymphoma", "Prolymphocytic Leukemia", "Diffuse Large Cell Non Hodgkins Lymphoma", "Lymphoblastic Lymphoma", "Burkitt Lymphoma", "High Grade Non-Hodgkin's Lymphoma, Adult", "Multiple Myeloma", "Juvenile Myelomonocytic Leukemia", "Biphenotypic/Undifferentiated/Prolymphocytic Leukemias", "MRD Positive Leukemia", "Natural Killer Cell Malignancies", "Acquired Bone Marrow Failure Syndromes" ], "interventions": [ { "name": "HSCT with TBI Regimen", "type": "BIOLOGICAL" }, { "name": "HSCT with Non-TBI Regimen", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Masonic Cancer Center, University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "60 Years", "sex": "ALL", "summary": "Up to 60 Years" }, "enrollment_count": 300, "start_date": "2018-03-30", "completion_date": "2028-06-10", "has_results": false, "last_update_posted_date": "2026-06-25", "last_synced_at": "2026-10-22T02:30:00.640Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT03314974" }, { "nct_id": "NCT00715910", "title": "The Long-term Antibody Persistence of GSK Biologicals' Meningococcal Vaccine GSK134612 in Healthy Adolescents/Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Infections, Meningococcal" ], "interventions": [ { "name": "Nimenrix", "type": "BIOLOGICAL" }, { "name": "Blood sampling", "type": "PROCEDURE" } ], "intervention_types": [ "BIOLOGICAL", "PROCEDURE" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "15 Years", "maximum_age": "30 Years", "sex": "ALL", "summary": "15 Years to 30 Years" }, "enrollment_count": 818, "start_date": "2008-07", "completion_date": "2013-10", "has_results": true, "last_update_posted_date": "2014-11-27", "last_synced_at": "2026-10-22T02:30:00.640Z", "location_count": 10, "location_summary": "Daly City, California • Fairfield, California • Redwood City, California + 6 more", "locations": [ { "city": "Daly City", "state": "California" }, { "city": "Fairfield", "state": "California" }, { "city": "Redwood City", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Vallejo", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00715910" }, { "nct_id": "NCT06940297", "title": "Dasatinib and Quercetin With CAR-T Therapy for the Treatment of Patients With Relapsed or Refractory Multiple Myeloma", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Recurrent Multiple Myeloma", "Refractory Multiple Myeloma" ], "interventions": [ { "name": "Biopsy Procedure", "type": "PROCEDURE" }, { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Bone Marrow Aspiration", "type": "PROCEDURE" }, { "name": "Bone Marrow Biopsy", "type": "PROCEDURE" }, { "name": "Ciltacabtagene Autoleucel", "type": "BIOLOGICAL" }, { "name": "Computed Tomography", "type": "PROCEDURE" }, { "name": "Cyclophosphamide", "type": "DRUG" }, { "name": "Dasatinib", "type": "DRUG" }, { "name": "Fludarabine", "type": "DRUG" }, { "name": "Positron Emission Tomography", "type": "PROCEDURE" }, { "name": "Quercetin", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "BIOLOGICAL", "DRUG" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 44, "start_date": "2025-09-18", "completion_date": "2031-08-15", "has_results": false, "last_update_posted_date": "2026-08-26", "last_synced_at": "2026-10-22T02:30:00.640Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT06940297" } ] }