{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Opt-in",
    "query": {
      "intervention": "Opt-in"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 264,
    "total_pages": 27,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Opt-in&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-10T13:34:42.550Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02017548",
      "title": "Default Options in Advance Directives",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "This Study Will Focus on Advance Care Planning Among Patients With Life-limiting Illnesses"
      ],
      "interventions": [
        {
          "name": "Life-extension default advance directive",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Comfort default advance directive",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 270,
      "start_date": "2014-01",
      "completion_date": "2016-11",
      "has_results": false,
      "last_update_posted_date": "2019-04-01",
      "last_synced_at": "2026-09-10T13:34:42.550Z",
      "location_count": 4,
      "location_summary": "Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02017548"
    },
    {
      "nct_id": "NCT04109027",
      "title": "Strengthening Neuro-Cognitive Skills for Success in School, Work and Beyond",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "TBI",
        "Cognitive Dysfunction"
      ],
      "interventions": [
        {
          "name": "BrainStrong-GSR",
          "type": "BEHAVIORAL"
        },
        {
          "name": "BrainStrong-OPT",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 120,
      "start_date": "2024-06-10",
      "completion_date": "2026-05-25",
      "has_results": false,
      "last_update_posted_date": "2025-11-17",
      "last_synced_at": "2026-09-10T13:34:42.550Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04109027"
    },
    {
      "nct_id": "NCT05609188",
      "title": "Black Economic Equity Movement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mental Health Wellness 1",
        "Health Care Utilization",
        "Financial Hardship",
        "Education, Professional"
      ],
      "interventions": [
        {
          "name": "Guaranteed Income",
          "type": "OTHER"
        },
        {
          "name": "Peer learning circles",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Financial coaching",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "24 Years",
        "sex": "ALL",
        "summary": "18 Years to 24 Years"
      },
      "enrollment_count": 300,
      "start_date": "2022-11-01",
      "completion_date": "2025-09-22",
      "has_results": false,
      "last_update_posted_date": "2026-06-05",
      "last_synced_at": "2026-09-10T13:34:42.550Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05609188"
    },
    {
      "nct_id": "NCT07525076",
      "title": "Implementation of an Opt-Out Testing and Rapid Diagnostic Strategy for Syphilis and HIV in Pregnant Patients Presenting to the Emergency Department",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV Infections",
        "Syphilis Infection"
      ],
      "interventions": [
        {
          "name": "Chembio HIV/Syphilis rapid Point of Care (POC) test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Laboratory-based HIV and syphilis testing",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "14 Years to 45 Years · Female only"
      },
      "enrollment_count": 1400,
      "start_date": "2026-04-15",
      "completion_date": "2028-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-13",
      "last_synced_at": "2026-09-10T13:34:42.550Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07525076"
    },
    {
      "nct_id": "NCT03516799",
      "title": "Acupuncture Intervention for AYA With Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Palliative Care"
      ],
      "interventions": [
        {
          "name": "Acupuncture",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "24 Years",
        "sex": "ALL",
        "summary": "13 Years to 24 Years"
      },
      "enrollment_count": 55,
      "start_date": "2018-08-13",
      "completion_date": "2019-11-08",
      "has_results": false,
      "last_update_posted_date": "2019-12-18",
      "last_synced_at": "2026-09-10T13:34:42.550Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03516799"
    },
    {
      "nct_id": "NCT06788977",
      "title": "External Trigeminal Nerve Stimulation for Migraine Treatment in Pregnancy",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pregnancy",
        "Migraine",
        "Headache",
        "Postpartum",
        "Depression",
        "Anxiety"
      ],
      "interventions": [
        {
          "name": "external Trigeminal Nerve Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cefaly Technology",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "44 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 44 Years · Female only"
      },
      "enrollment_count": 550,
      "start_date": "2024-11-25",
      "completion_date": "2030-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-15",
      "last_synced_at": "2026-09-10T13:34:42.550Z",
      "location_count": 1,
      "location_summary": "Darien, Connecticut",
      "locations": [
        {
          "city": "Darien",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06788977"
    },
    {
      "nct_id": "NCT00940511",
      "title": "Effects of Coordinated Care for Disabled Medicaid Recipients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Conditions Faced by Medicaid Recipients With Disabilities"
      ],
      "interventions": [
        {
          "name": "Coordinated care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "MDRC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 2618,
      "start_date": "2009-08",
      "completion_date": "2013-01",
      "has_results": false,
      "last_update_posted_date": "2016-03-16",
      "last_synced_at": "2026-09-10T13:34:42.550Z",
      "location_count": 1,
      "location_summary": "Jefferson County, Colorado",
      "locations": [
        {
          "city": "Jefferson County",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00940511"
    },
    {
      "nct_id": "NCT03564587",
      "title": "Improving Health-Promoting Behaviors in Adolescent Cancer Survivors Using AWAKE: A Feasibility Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Health Behavior"
      ],
      "interventions": [
        {
          "name": "AWAKE",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "13 Years to 17 Years"
      },
      "enrollment_count": 92,
      "start_date": "2018-06-20",
      "completion_date": "2020-09-15",
      "has_results": false,
      "last_update_posted_date": "2021-12-08",
      "last_synced_at": "2026-09-10T13:34:42.550Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03564587"
    },
    {
      "nct_id": "NCT03526380",
      "title": "The OPT-IN Project",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid-Related Disorders"
      ],
      "interventions": [
        {
          "name": "Behavioral: the OPT-IN Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 92,
      "start_date": "2018-10-11",
      "completion_date": "2020-06-30",
      "has_results": false,
      "last_update_posted_date": "2020-08-13",
      "last_synced_at": "2026-09-10T13:34:42.550Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03526380"
    },
    {
      "nct_id": "NCT05724615",
      "title": "Default Bulk Ordering and Text Messaging to Enhance Outreach for Lipid Screening (Missing Lipids)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atherosclerotic Cardiovascular Disease"
      ],
      "interventions": [
        {
          "name": "Outreach + Bulk ordering",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Outreach + Bulk ordering + Text Based Reminders and Scheduling assistance",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "20 Years to 75 Years"
      },
      "enrollment_count": 1000,
      "start_date": "2023-06-05",
      "completion_date": "2023-12-07",
      "has_results": false,
      "last_update_posted_date": "2024-01-05",
      "last_synced_at": "2026-09-10T13:34:42.550Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05724615"
    }
  ]
}