{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Opti-Free",
    "query": {
      "intervention": "Opti-Free"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 26,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Opti-Free&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-10T01:21:44.918Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03034928",
      "title": "Clinical Biocompatibility Evaluation of Contact Lens Coatings",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors",
        "Ametropia"
      ],
      "interventions": [
        {
          "name": "Contact lens with investigational coating 1",
          "type": "DEVICE"
        },
        {
          "name": "Balafilcon A contact lens",
          "type": "DEVICE"
        },
        {
          "name": "OPTI-FREE® RepleniSH® MPDS",
          "type": "DEVICE"
        },
        {
          "name": "Contact lens with investigational coating 2",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 33,
      "start_date": "2017-02-14",
      "completion_date": "2017-03-14",
      "has_results": true,
      "last_update_posted_date": "2020-02-18",
      "last_synced_at": "2026-09-10T01:21:44.918Z",
      "location_count": 1,
      "location_summary": "Johns Creek, Georgia",
      "locations": [
        {
          "city": "Johns Creek",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03034928"
    },
    {
      "nct_id": "NCT06592521",
      "title": "OPTI-FREE Family STUDY",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Contact Lens Care"
      ],
      "interventions": [
        {
          "name": "OPTI-FREE EXPRESS MPDS and Alcon contact lens case",
          "type": "DEVICE"
        },
        {
          "name": "OPTI-FREE PureMoist MPDS and Alcon contact lens case",
          "type": "DEVICE"
        },
        {
          "name": "OPTI-FREE REPLENISH MPDS and Alcon contact lens case",
          "type": "DEVICE"
        },
        {
          "name": "Habitual contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "7 Years to 17 Years"
      },
      "enrollment_count": 0,
      "start_date": "2025-10",
      "completion_date": "2026-01",
      "has_results": false,
      "last_update_posted_date": "2025-09-16",
      "last_synced_at": "2026-09-10T01:21:44.918Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06592521"
    },
    {
      "nct_id": "NCT01211535",
      "title": "Subjective Comfort With Multipurpose Care Solutions in Soft Contact Lens Wearers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia",
        "Astigmatism",
        "Refractive Error"
      ],
      "interventions": [
        {
          "name": "OPTI-FREE RepleniSH multipurpose solution",
          "type": "DEVICE"
        },
        {
          "name": "ReNu Biotrue multipurpose solution",
          "type": "DEVICE"
        },
        {
          "name": "Silicone hydrogel contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 104,
      "start_date": "2010-09",
      "completion_date": "2010-11",
      "has_results": true,
      "last_update_posted_date": "2012-11-12",
      "last_synced_at": "2026-09-10T01:21:44.918Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01211535"
    },
    {
      "nct_id": "NCT00961051",
      "title": "Evaluation of an Investigational Multi-Purpose Solution (MPS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Study Focus is Healthy Contact Lens Wearers"
      ],
      "interventions": [
        {
          "name": "Investigational MPS",
          "type": "DEVICE"
        },
        {
          "name": "Opti-Free",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Optics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 270,
      "start_date": "2009-02",
      "completion_date": "2009-11",
      "has_results": true,
      "last_update_posted_date": "2014-01-07",
      "last_synced_at": "2026-09-10T01:21:44.918Z",
      "location_count": 9,
      "location_summary": "San Diego, California • Waipahu, Hawaii • Warrensburg, Missouri + 6 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Waipahu",
          "state": "Hawaii"
        },
        {
          "city": "Warrensburg",
          "state": "Missouri"
        },
        {
          "city": "Athens",
          "state": "Ohio"
        },
        {
          "city": "Beachwood",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00961051"
    },
    {
      "nct_id": "NCT00724269",
      "title": "Comparison of OPTI-FREE RepleniSH and ReNu Multi-Plus Lens Care Regimens on Corneal Epithelium",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Contact Lens Wear"
      ],
      "interventions": [
        {
          "name": "OPTI-FREE RepleniSH",
          "type": "DEVICE"
        },
        {
          "name": "ReNu MultiPlus MPS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2009-10",
      "completion_date": "2011-07",
      "has_results": false,
      "last_update_posted_date": "2012-10-01",
      "last_synced_at": "2026-09-10T01:21:44.918Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00724269"
    },
    {
      "nct_id": "NCT00519948",
      "title": "Comfort and Cleaning Evaluation of Multipurpose Solutions in Contact Lens Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Patient Comfort",
        "Lens Cleanliness"
      ],
      "interventions": [
        {
          "name": "new MPS, opti-free express no rub MPS",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Innovative Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": null,
      "completion_date": "2008-06",
      "has_results": false,
      "last_update_posted_date": "2008-06-19",
      "last_synced_at": "2026-09-10T01:21:44.918Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00519948"
    },
    {
      "nct_id": "NCT00733291",
      "title": "Evaluation of Daily Disposable Lenses With Multi-Purpose Solution (MPS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Nelfilcon A contact lens",
          "type": "DEVICE"
        },
        {
          "name": "Etafilcon A contact lens",
          "type": "DEVICE"
        },
        {
          "name": "FID 107027 solution",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 64,
      "start_date": "2008-01",
      "completion_date": "2008-02",
      "has_results": true,
      "last_update_posted_date": "2011-12-28",
      "last_synced_at": "2026-09-10T01:21:44.918Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00733291"
    },
    {
      "nct_id": "NCT04055519",
      "title": "Clinical Performance Assessment of a Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Lehfilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Multi-purpose disinfection solution",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2019-09-19",
      "completion_date": "2019-12-03",
      "has_results": true,
      "last_update_posted_date": "2021-05-13",
      "last_synced_at": "2026-09-10T01:21:44.918Z",
      "location_count": 3,
      "location_summary": "Maitland, Florida • Bloomington, Illinois • Memphis, Tennessee",
      "locations": [
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Bloomington",
          "state": "Illinois"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04055519"
    },
    {
      "nct_id": "NCT00995189",
      "title": "Clinical Evaluation of the Causes of Contact Lens Related Dry Eye",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Contact Lens Related Dry Eye"
      ],
      "interventions": [
        {
          "name": "Opti-Free RepleniSH",
          "type": "DEVICE"
        },
        {
          "name": "ReNu MultiPlus",
          "type": "DEVICE"
        },
        {
          "name": "Contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 159,
      "start_date": "2009-08",
      "completion_date": "2010-04",
      "has_results": false,
      "last_update_posted_date": "2016-11-17",
      "last_synced_at": "2026-09-10T01:21:44.918Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00995189"
    },
    {
      "nct_id": "NCT04789382",
      "title": "Three Daily Wear Monthly Replacement Silicone Hydrogel Contact Lenses With Two Multi-purpose Disinfecting Solution Combinations",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "LID018869+RepleniSH",
          "type": "DEVICE"
        },
        {
          "name": "LID018869+Biotrue",
          "type": "DEVICE"
        },
        {
          "name": "Biofinity+RepleniSH",
          "type": "DEVICE"
        },
        {
          "name": "PV+Biotrue",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2021-04-07",
      "completion_date": "2021-05-07",
      "has_results": true,
      "last_update_posted_date": "2022-05-25",
      "last_synced_at": "2026-09-10T01:21:44.918Z",
      "location_count": 1,
      "location_summary": "Maitland, Florida",
      "locations": [
        {
          "city": "Maitland",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04789382"
    }
  ]
}