{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Optical+Imaging",
    "query": {
      "intervention": "Optical Imaging"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 460,
    "total_pages": 46,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Optical+Imaging&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T07:51:40.716Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03324997",
      "title": "Restylane Silk for Treatment of Chest Wrinkles",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Wrinkle"
      ],
      "interventions": [
        {
          "name": "Restylane Silk",
          "type": "DRUG"
        },
        {
          "name": "Saline",
          "type": "DRUG"
        },
        {
          "name": "Optical Coherence Tomography",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Heidi Waldorf",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "25 Years to 55 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2018-01-28",
      "completion_date": "2018-01-28",
      "has_results": false,
      "last_update_posted_date": "2018-03-06",
      "last_synced_at": "2026-09-03T07:51:40.716Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03324997"
    },
    {
      "nct_id": "NCT01281488",
      "title": "Fluorescence Imaging in Finding Tumors in Patients With Kidney Tumors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Recurrent Renal Cell Cancer",
        "Stage I Renal Cell Cancer",
        "Stage II Renal Cell Cancer"
      ],
      "interventions": [
        {
          "name": "fluorescence imaging",
          "type": "PROCEDURE"
        },
        {
          "name": "laparoscopic surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "indocyanine green",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "City of Hope Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 28,
      "start_date": "2011-10-20",
      "completion_date": "2017-10-09",
      "has_results": false,
      "last_update_posted_date": "2017-10-13",
      "last_synced_at": "2026-09-03T07:51:40.716Z",
      "location_count": 1,
      "location_summary": "Duarte, California",
      "locations": [
        {
          "city": "Duarte",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01281488"
    },
    {
      "nct_id": "NCT06374498",
      "title": "Study to Determine the Clinical Significance of Intravascular OCT-NIRAF",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Diseases",
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "OCT-NIRAF",
          "type": "DEVICE"
        },
        {
          "name": "LUMISIGHT Injection",
          "type": "DRUG"
        },
        {
          "name": "OCT-NIRAF following LUMISIGHT Injection",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2024-07-08",
      "completion_date": "2028-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-14",
      "last_synced_at": "2026-09-03T07:51:40.716Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06374498"
    },
    {
      "nct_id": "NCT03713268",
      "title": "Intraoperative OCT Guidance of Intraocular Surgery II",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Macular Holes",
        "Epiretinal Membrane",
        "Diabetic Retinopathy",
        "Retinal Detachment",
        "Retinal Disease",
        "Preretinal Fibrosis",
        "Cataract",
        "Ocular Tumor",
        "Strabismus",
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Microscope integrated optical coherence tomography",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "4 Weeks",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "4 Weeks and older"
      },
      "enrollment_count": 262,
      "start_date": "2018-09-30",
      "completion_date": "2027-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-06",
      "last_synced_at": "2026-09-03T07:51:40.716Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03713268"
    },
    {
      "nct_id": "NCT03694626",
      "title": "Objectively Diagnose and Monitor Treatment of Light Sensitivity",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Photophobia",
        "Traumatic Brain Injury",
        "Migraine"
      ],
      "interventions": [
        {
          "name": "Pupillography",
          "type": "DEVICE"
        },
        {
          "name": "Ocular Coherence Tomography (OCT)",
          "type": "DEVICE"
        },
        {
          "name": "Wrist-watch sensor device",
          "type": "DEVICE"
        },
        {
          "name": "Videography",
          "type": "DEVICE"
        },
        {
          "name": "Electrophysiology",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Randy Kardon",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 120,
      "start_date": "2019-07-11",
      "completion_date": "2028-01-01",
      "has_results": false,
      "last_update_posted_date": "2025-11-24",
      "last_synced_at": "2026-09-03T07:51:40.716Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03694626"
    },
    {
      "nct_id": "NCT05863195",
      "title": "Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Metastatic Colorectal Carcinoma",
        "Metastatic Malignant Neoplasm in the Liver",
        "Stage IV Colorectal Cancer AJCC v8",
        "Unresectable Colorectal Carcinoma"
      ],
      "interventions": [
        {
          "name": "Bevacizumab",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Cetuximab",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Computed Tomography",
          "type": "PROCEDURE"
        },
        {
          "name": "Floxuridine",
          "type": "DRUG"
        },
        {
          "name": "Fluorouracil",
          "type": "DRUG"
        },
        {
          "name": "Implantation",
          "type": "PROCEDURE"
        },
        {
          "name": "Intrahepatic Infusion Procedure",
          "type": "PROCEDURE"
        },
        {
          "name": "Irinotecan",
          "type": "DRUG"
        },
        {
          "name": "Leucovorin",
          "type": "DRUG"
        },
        {
          "name": "Oxaliplatin",
          "type": "DRUG"
        },
        {
          "name": "Panitumumab",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Single Photon Emission Computed Tomography",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "ECOG-ACRIN Cancer Research Group",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 408,
      "start_date": "2023-10-19",
      "completion_date": "2034-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-18",
      "last_synced_at": "2026-09-03T07:51:40.716Z",
      "location_count": 62,
      "location_summary": "Birmingham, Alabama • Gilbert, Arizona • Phoenix, Arizona + 48 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Gilbert",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Sun City",
          "state": "Arizona"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05863195"
    },
    {
      "nct_id": "NCT01295931",
      "title": "Nuclear and Near-Infrared (NIR) Imaging in Melanoma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Melanoma"
      ],
      "interventions": [
        {
          "name": "Indocyanine Green (IC-Green)",
          "type": "DRUG"
        },
        {
          "name": "Imaging",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2011-02",
      "completion_date": "2014-10",
      "has_results": false,
      "last_update_posted_date": "2015-10-07",
      "last_synced_at": "2026-09-03T07:51:40.716Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01295931"
    },
    {
      "nct_id": "NCT07024719",
      "title": "4D Duke Microscope Integrated Optical Coherence Tomography in a Zeiss Artevo 800",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Corneal Diseases",
        "Retinal Diseases",
        "Ocular Diseases"
      ],
      "interventions": [
        {
          "name": "4D MIOCT integrated into a Zeiss Artevo 800",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2025-07-24",
      "completion_date": "2026-10",
      "has_results": false,
      "last_update_posted_date": "2026-01-16",
      "last_synced_at": "2026-09-03T07:51:40.716Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07024719"
    },
    {
      "nct_id": "NCT03640494",
      "title": "Bedside Optical Retinal Assessment of Hypoxic Ischemic Encephalopathy in Infants",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypoxic-Ischemic Encephalopathy"
      ],
      "interventions": [
        {
          "name": "Optical Coherence Tomography",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "20 Days",
        "sex": "ALL",
        "summary": "Up to 20 Days"
      },
      "enrollment_count": 57,
      "start_date": "2018-08-28",
      "completion_date": "2021-02-28",
      "has_results": false,
      "last_update_posted_date": "2021-04-08",
      "last_synced_at": "2026-09-03T07:51:40.716Z",
      "location_count": 2,
      "location_summary": "Durham, North Carolina • Salt Lake City, Utah",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03640494"
    },
    {
      "nct_id": "NCT01212029",
      "title": "Testing and Calibration of Non-Invasive Optical Imaging Technology for Functional Brain Imaging",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognition"
      ],
      "interventions": [
        {
          "name": "Behavioral measures",
          "type": "BEHAVIORAL"
        },
        {
          "name": "fNIRS Devices & Application",
          "type": "DEVICE"
        },
        {
          "name": "Physiological measures",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 159,
      "start_date": "2011-09-08",
      "completion_date": "2024-10-02",
      "has_results": true,
      "last_update_posted_date": "2025-04-17",
      "last_synced_at": "2026-09-03T07:51:40.716Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01212029"
    }
  ]
}