{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Optical+Spectroscopy",
    "query": {
      "intervention": "Optical Spectroscopy"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 93,
    "total_pages": 10,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Optical+Spectroscopy&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-08T14:00:29.439Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02340468",
      "title": "Breast Tumor Oxygenation During Exercise",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Breast Tumor"
      ],
      "interventions": [
        {
          "name": "diffuse optical spectroscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "21 Years to 70 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2015-04",
      "completion_date": "2018-01",
      "has_results": false,
      "last_update_posted_date": "2022-11-01",
      "last_synced_at": "2026-09-08T14:00:29.439Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02340468"
    },
    {
      "nct_id": "NCT07610746",
      "title": "Cerebral Physiology of NOWS",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neonatal Opioid Withdrawal",
        "Neonatal Opioid Withdrawal Syndrome",
        "Opioid Use Disorder",
        "Intrauterine Exposure"
      ],
      "interventions": [
        {
          "name": "FD-NIRS and DCS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Day",
        "sex": "ALL",
        "summary": "Up to 1 Day"
      },
      "enrollment_count": 46,
      "start_date": "2026-08-11",
      "completion_date": "2027-08",
      "has_results": false,
      "last_update_posted_date": "2026-08-19",
      "last_synced_at": "2026-09-08T14:00:29.439Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07610746"
    },
    {
      "nct_id": "NCT01034670",
      "title": "Advanced Gastrointestinal Endoscopic Imaging",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gastrointestinal Diseases",
        "Gastric (Stomach) Cancer",
        "Gastrointestinal Stromal Tumor (GIST)"
      ],
      "interventions": [
        {
          "name": "Dual axis endoscopic microscope",
          "type": "DEVICE"
        },
        {
          "name": "wide field fluorescence system",
          "type": "DEVICE"
        },
        {
          "name": "CellVizio",
          "type": "DEVICE"
        },
        {
          "name": "fluorescent Peptide",
          "type": "DRUG"
        },
        {
          "name": "fluorescein",
          "type": "DRUG"
        },
        {
          "name": "indocyanine green",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3,
      "start_date": "2009-06",
      "completion_date": "2017-09-25",
      "has_results": true,
      "last_update_posted_date": "2024-06-26",
      "last_synced_at": "2026-09-08T14:00:29.439Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01034670"
    },
    {
      "nct_id": "NCT05859334",
      "title": "Testing the Anti-cancer Drug Erdafitinib for Brain Cancers That Have Returned or Progressed Following Treatment",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Recurrent Glioma",
        "Recurrent WHO Grade 2 Glioma",
        "Recurrent WHO Grade 3 Glioma",
        "Recurrent WHO Grade 4 Glioma"
      ],
      "interventions": [
        {
          "name": "Biospecimen Collection",
          "type": "PROCEDURE"
        },
        {
          "name": "Erdafitinib",
          "type": "DRUG"
        },
        {
          "name": "Magnetic Resonance Imaging",
          "type": "PROCEDURE"
        },
        {
          "name": "Optical Coherence Tomography",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2024-01-04",
      "completion_date": "2026-10-23",
      "has_results": false,
      "last_update_posted_date": "2026-08-17",
      "last_synced_at": "2026-09-08T14:00:29.439Z",
      "location_count": 27,
      "location_summary": "Aurora, Colorado • Coral Gables, Florida • Deerfield Beach, Florida + 19 more",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Coral Gables",
          "state": "Florida"
        },
        {
          "city": "Deerfield Beach",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Shiloh",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05859334"
    },
    {
      "nct_id": "NCT04743362",
      "title": "A Study of Noninvasive Methods to Evaluate Skin and Mucosal Conditions",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Skin Lesion",
        "Mucosal Lesion"
      ],
      "interventions": [
        {
          "name": "Dermoscopic imaging",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "3-dimensional total body photography",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Confocal microscopy",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Optical Coherence Tomography imaging",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Ultrasound",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Hyperspectral imaging",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Electrical impedance spectroscopy",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Patient self-imaging",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 5010,
      "start_date": "2021-02-02",
      "completion_date": "2031-08-02",
      "has_results": false,
      "last_update_posted_date": "2026-04-23",
      "last_synced_at": "2026-09-08T14:00:29.439Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04743362"
    },
    {
      "nct_id": "NCT01277263",
      "title": "Predicting Pathological Response Within the 1st Week of Chemotherapy Using Diffuse Optical Spectroscopic Imaging",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Diffuse Optical Spectroscopy Imaging",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "21 Years to 75 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2010-12",
      "completion_date": "2018-12",
      "has_results": false,
      "last_update_posted_date": "2022-11-01",
      "last_synced_at": "2026-09-08T14:00:29.439Z",
      "location_count": 3,
      "location_summary": "Costa Mesa, California • Irvine, California • Orange, California",
      "locations": [
        {
          "city": "Costa Mesa",
          "state": "California"
        },
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01277263"
    },
    {
      "nct_id": "NCT01765205",
      "title": "Newborn Screening for Critical Congenital Heart Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congenital Cardiovascular Malformation"
      ],
      "interventions": [
        {
          "name": "Pulse Oximetry using the INVOS (In Vivo Optical Spectroscopy) Cerebral/Somatic Oximeter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Hours",
        "maximum_age": "2 Weeks",
        "sex": "ALL",
        "summary": "12 Hours to 2 Weeks"
      },
      "enrollment_count": 20,
      "start_date": "2010-03",
      "completion_date": "2014-01",
      "has_results": false,
      "last_update_posted_date": "2014-03-14",
      "last_synced_at": "2026-09-08T14:00:29.439Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01765205"
    },
    {
      "nct_id": "NCT03293888",
      "title": "Spectral Analysis Probe to Identify Glioblastoma Cells",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Glioblastoma"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2017-10-31",
      "completion_date": "2018-09-30",
      "has_results": false,
      "last_update_posted_date": "2019-01-25",
      "last_synced_at": "2026-09-08T14:00:29.439Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03293888"
    },
    {
      "nct_id": "NCT00786721",
      "title": "Mitochondria and Metabolic Syndrome in a Southern California Chinese Cohort",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Metabolic Syndrome",
        "Type 2 Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Diffuse Optical Spectroscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 9,
      "start_date": "2006-11",
      "completion_date": "2010-08",
      "has_results": false,
      "last_update_posted_date": "2022-11-01",
      "last_synced_at": "2026-09-08T14:00:29.439Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00786721"
    },
    {
      "nct_id": "NCT02168114",
      "title": "Magnetic Resonance and Optical Imaging of Dystrophic and Damaged Muscle",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Duchenne Muscular Dystrophy"
      ],
      "interventions": [
        {
          "name": "Exercising",
          "type": "OTHER"
        },
        {
          "name": "Optical and Magnetic Resonance Imaging and Spectroscopy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "55 Years",
        "sex": "MALE",
        "summary": "10 Years to 55 Years · Male only"
      },
      "enrollment_count": 17,
      "start_date": "2014-07",
      "completion_date": "2018-01-08",
      "has_results": false,
      "last_update_posted_date": "2018-01-12",
      "last_synced_at": "2026-09-08T14:00:29.439Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02168114"
    }
  ]
}