{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Optical+Spectroscopy+Measurement&page=2",
    "query": {
      "intervention": "Optical Spectroscopy Measurement",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 25,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Optical+Spectroscopy+Measurement&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Optical+Spectroscopy+Measurement&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-21T21:05:05.171Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04031521",
      "title": "Near Infrared Spectroscopy in Sickle Cell Pediatric Patients",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sickle Cell Disease"
      ],
      "interventions": [
        {
          "name": "Near infrared spectroscopy",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Children's National Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "6 Years to 21 Years"
      },
      "enrollment_count": 0,
      "start_date": "2019-06-26",
      "completion_date": "2023-09-03",
      "has_results": false,
      "last_update_posted_date": "2023-09-14",
      "last_synced_at": "2026-10-21T21:05:05.171Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04031521"
    },
    {
      "nct_id": "NCT00918788",
      "title": "Laser Spectroscopy of Breast Tissue Through a Needle Device",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "biologic sample preservation procedure",
          "type": "OTHER"
        },
        {
          "name": "immunohistochemistry staining method",
          "type": "OTHER"
        },
        {
          "name": "light microscopy",
          "type": "OTHER"
        },
        {
          "name": "medical chart review",
          "type": "OTHER"
        },
        {
          "name": "histopathologic examination",
          "type": "PROCEDURE"
        },
        {
          "name": "needle biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "spectroscopy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Case Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 17,
      "start_date": "2008-04",
      "completion_date": "2013-02",
      "has_results": false,
      "last_update_posted_date": "2013-08-22",
      "last_synced_at": "2026-10-21T21:05:05.171Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00918788"
    },
    {
      "nct_id": "NCT01765205",
      "title": "Newborn Screening for Critical Congenital Heart Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congenital Cardiovascular Malformation"
      ],
      "interventions": [
        {
          "name": "Pulse Oximetry using the INVOS (In Vivo Optical Spectroscopy) Cerebral/Somatic Oximeter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Hours",
        "maximum_age": "2 Weeks",
        "sex": "ALL",
        "summary": "12 Hours to 2 Weeks"
      },
      "enrollment_count": 20,
      "start_date": "2010-03",
      "completion_date": "2014-01",
      "has_results": false,
      "last_update_posted_date": "2014-03-14",
      "last_synced_at": "2026-10-21T21:05:05.171Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01765205"
    },
    {
      "nct_id": "NCT00540683",
      "title": "Measurement of the Distribution of Optical Properties in Adult Human Muscle",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Muscle Disorder"
      ],
      "interventions": [
        {
          "name": "Diffuse Optical Spectroscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 0,
      "start_date": "2004-10",
      "completion_date": "2018-07",
      "has_results": false,
      "last_update_posted_date": "2022-10-20",
      "last_synced_at": "2026-10-21T21:05:05.171Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00540683"
    },
    {
      "nct_id": "NCT00540540",
      "title": "Measurements of Breast Tissue Optical Properties",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Accessory; Breast Tissue"
      ],
      "interventions": [
        {
          "name": "Diffuse Optical Spectroscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 75 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "1995-12",
      "completion_date": "2018-07",
      "has_results": false,
      "last_update_posted_date": "2022-10-20",
      "last_synced_at": "2026-10-21T21:05:05.171Z",
      "location_count": 4,
      "location_summary": "Costa Mesa, California • Irvine, California • La Jolla San Diego, California + 1 more",
      "locations": [
        {
          "city": "Costa Mesa",
          "state": "California"
        },
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "La Jolla San Diego",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00540540"
    },
    {
      "nct_id": "NCT00488332",
      "title": "An Exploratory Study on Optical Assessment of Oral Mucositis",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Head and Neck Cancer",
        "Oral Mucositis"
      ],
      "interventions": [
        {
          "name": "Optical Coherence Tomography",
          "type": "PROCEDURE"
        },
        {
          "name": "Fluorescence Spectroscopy",
          "type": "PROCEDURE"
        },
        {
          "name": "Pain Scale Questionnaire",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BEHAVIORAL"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2006-03",
      "completion_date": "2010-07",
      "has_results": false,
      "last_update_posted_date": "2012-07-20",
      "last_synced_at": "2026-10-21T21:05:05.171Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00488332"
    },
    {
      "nct_id": "NCT02995837",
      "title": "Cerebral Blood Flow and Childhood Obstructive Sleep Apnea",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Obstructive Sleep Apnea Syndrome"
      ],
      "interventions": [
        {
          "name": "Sleep Study",
          "type": "OTHER"
        },
        {
          "name": "Neurocognitive Testing",
          "type": "OTHER"
        },
        {
          "name": "CBF During Wakefulness",
          "type": "OTHER"
        },
        {
          "name": "CBF During Sleep",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "6 Years to 12 Years"
      },
      "enrollment_count": 47,
      "start_date": "2016-10",
      "completion_date": "2022-01-01",
      "has_results": true,
      "last_update_posted_date": "2024-07-09",
      "last_synced_at": "2026-10-21T21:05:05.171Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02995837"
    },
    {
      "nct_id": "NCT01982357",
      "title": "Measurement of Neonatal Microvascular Hemodynamics Using Non-invasive Optical Technologies",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Infant, Premature, Diseases"
      ],
      "interventions": [
        {
          "name": "Laser Speckle Imaging and Diffuse Optical Spectroscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Minute",
        "maximum_age": "1 Month",
        "sex": "ALL",
        "summary": "1 Minute to 1 Month"
      },
      "enrollment_count": 32,
      "start_date": "2013-07-17",
      "completion_date": "2015-06-30",
      "has_results": false,
      "last_update_posted_date": "2022-11-01",
      "last_synced_at": "2026-10-21T21:05:05.171Z",
      "location_count": 1,
      "location_summary": "Orange, California",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01982357"
    },
    {
      "nct_id": "NCT07610746",
      "title": "Cerebral Physiology of NOWS",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neonatal Opioid Withdrawal",
        "Neonatal Opioid Withdrawal Syndrome",
        "Opioid Use Disorder",
        "Intrauterine Exposure"
      ],
      "interventions": [
        {
          "name": "FD-NIRS and DCS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Day",
        "sex": "ALL",
        "summary": "Up to 1 Day"
      },
      "enrollment_count": 46,
      "start_date": "2026-08-11",
      "completion_date": "2027-08",
      "has_results": false,
      "last_update_posted_date": "2026-08-19",
      "last_synced_at": "2026-10-21T21:05:05.171Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07610746"
    },
    {
      "nct_id": "NCT02169726",
      "title": "A Pilot Study Non-Invasive Guidance for Therapeutic Ultrasound Treatment of Lower Back Muscle Injuries",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Injury; Muscle, Back, Lower"
      ],
      "interventions": [
        {
          "name": "Diffuse Optical Spectroscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2013-12",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2022-11-01",
      "last_synced_at": "2026-10-21T21:05:05.171Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02169726"
    }
  ]
}