{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Oral+bovine+type+I+collagen",
    "query": {
      "intervention": "Oral bovine type I collagen"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 5,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-02T10:37:25.987Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02579187",
      "title": "MicroRNA and MicroRNA Inhibitors Socket Study, Pilot Clinical Trial",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Tooth Extraction Status Nos"
      ],
      "interventions": [
        {
          "name": "tooth extraction",
          "type": "PROCEDURE"
        },
        {
          "name": "CBCT scan",
          "type": "RADIATION"
        },
        {
          "name": "Anesthesia",
          "type": "DRUG"
        },
        {
          "name": "clinical measurements",
          "type": "OTHER"
        },
        {
          "name": "Biodegradable sponge (type I bovine collagen)",
          "type": "DRUG"
        },
        {
          "name": "10µg of pSil-miR200c",
          "type": "DRUG"
        },
        {
          "name": "cross mattress suture",
          "type": "PROCEDURE"
        },
        {
          "name": "10µg of PMIS miR200a plasmids",
          "type": "DRUG"
        },
        {
          "name": "5µg of pSil-miR200c and 5µg of PMIS miR200a",
          "type": "DRUG"
        },
        {
          "name": "Blood",
          "type": "PROCEDURE"
        },
        {
          "name": "Photos/videos",
          "type": "OTHER"
        },
        {
          "name": "Wound fluid",
          "type": "PROCEDURE"
        },
        {
          "name": "saliva",
          "type": "PROCEDURE"
        },
        {
          "name": "periapical xray",
          "type": "RADIATION"
        },
        {
          "name": "PVS impression",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "RADIATION",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Gustavo Avila-Ortiz DDS, MS, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "25 Years to 65 Years"
      },
      "enrollment_count": 0,
      "start_date": "2025-12-31",
      "completion_date": "2030-09",
      "has_results": false,
      "last_update_posted_date": "2019-07-17",
      "last_synced_at": "2026-10-02T10:37:25.987Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02579187"
    },
    {
      "nct_id": "NCT05419778",
      "title": "Alveolar Ridge Preservation Procedures",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alveolar Ridge Preservation"
      ],
      "interventions": [
        {
          "name": "Osteogen plug®",
          "type": "DEVICE"
        },
        {
          "name": "MInerOss®",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Tennessee",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 14,
      "start_date": "2019-02-08",
      "completion_date": "2021-01-11",
      "has_results": false,
      "last_update_posted_date": "2022-07-08",
      "last_synced_at": "2026-10-02T10:37:25.987Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05419778"
    },
    {
      "nct_id": "NCT00005675",
      "title": "Oral Type I Collagen for Relieving Scleroderma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Scleroderma",
        "Connective Tissue Diseases"
      ],
      "interventions": [
        {
          "name": "Oral bovine type I collagen",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 168,
      "start_date": "2000-04",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2010-05-25",
      "last_synced_at": "2026-10-02T10:37:25.987Z",
      "location_count": 12,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • Farmington, Connecticut + 9 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Farmington",
          "state": "Connecticut"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00005675"
    },
    {
      "nct_id": "NCT01134081",
      "title": "Expression of Angiogenic Biomarkers During Healing of Intra-Oral Soft Tissue Engineered Grafts",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingival Recession"
      ],
      "interventions": [
        {
          "name": "CelTx™",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Free Gingival Graft",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "PROCEDURE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2008-01",
      "completion_date": "2008-12",
      "has_results": true,
      "last_update_posted_date": "2017-08-21",
      "last_synced_at": "2026-10-02T10:37:25.987Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01134081"
    },
    {
      "nct_id": "NCT05505084",
      "title": "Alveolar Ridge Preservation Following Tooth Extraction.",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Tooth Fractures",
        "Tooth Extraction Status Nos",
        "Caries"
      ],
      "interventions": [
        {
          "name": "Tooth extraction and ridge preservation using different barrier mermbranes",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 47,
      "start_date": "2022-08-15",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-08",
      "last_synced_at": "2026-10-02T10:37:25.987Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05505084"
    }
  ]
}