{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Oral+hygiene+measures",
    "query": {
      "intervention": "Oral hygiene measures"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-20T02:54:11.182Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00779909",
      "title": "Dose-dependent Anti-inflammatory Effects of Vitamin D in a Human Gingivitis Model",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "vitamin D3",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Boston University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 35,
      "start_date": "2008-12",
      "completion_date": "2011-09",
      "has_results": true,
      "last_update_posted_date": "2017-10-02",
      "last_synced_at": "2026-09-20T02:54:11.182Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00779909"
    },
    {
      "nct_id": "NCT05470023",
      "title": "Imaging-based Assessment of Oral Biofilm and Gingival Health",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Plaque, Dental",
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "OTC Toothpastes or Mouthrinses",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 275,
      "start_date": "2022-09-01",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2025-12-23",
      "last_synced_at": "2026-09-20T02:54:11.182Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05470023"
    },
    {
      "nct_id": "NCT01584024",
      "title": "Resin Infiltration to Arrest Early Tooth Decay",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Resin infiltration",
          "type": "DEVICE"
        },
        {
          "name": "Sham treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "24 Years",
        "sex": "ALL",
        "summary": "18 Years to 24 Years"
      },
      "enrollment_count": 42,
      "start_date": "2013-03",
      "completion_date": "2017-12-31",
      "has_results": true,
      "last_update_posted_date": "2019-02-12",
      "last_synced_at": "2026-09-20T02:54:11.182Z",
      "location_count": 1,
      "location_summary": "West Point, New York",
      "locations": [
        {
          "city": "West Point",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01584024"
    },
    {
      "nct_id": "NCT03237624",
      "title": "Functional Chewing Gum in Reduction of Gingival Inflammation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Functional Chitosan Chewing Gum",
          "type": "DEVICE"
        },
        {
          "name": "Control Chewing Gum",
          "type": "DEVICE"
        },
        {
          "name": "Oral hygiene measures",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2018-01-31",
      "completion_date": "2020-01-31",
      "has_results": false,
      "last_update_posted_date": "2024-11-26",
      "last_synced_at": "2026-09-20T02:54:11.182Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03237624"
    },
    {
      "nct_id": "NCT06063876",
      "title": "Experimental Peri-implant Mucositis on Implant Sites That Were Previously Treated With or Without Implantoplasty",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Peri-implant Mucositis",
        "Peri-Implantitis"
      ],
      "interventions": [
        {
          "name": "Induction of experimental peri-implant mucositis",
          "type": "PROCEDURE"
        },
        {
          "name": "Resolution of experimental peri-implant mucositis",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2023-09-05",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2026-07-07",
      "last_synced_at": "2026-09-20T02:54:11.182Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06063876"
    },
    {
      "nct_id": "NCT01496456",
      "title": "Radiographic Progression of Infiltrated Caries Lesions In-vivo",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Resin infiltration",
          "type": "DEVICE"
        },
        {
          "name": "Caries management",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "14 Years to 35 Years"
      },
      "enrollment_count": 17,
      "start_date": "2010-05",
      "completion_date": "2014-07",
      "has_results": true,
      "last_update_posted_date": "2017-08-08",
      "last_synced_at": "2026-09-20T02:54:11.182Z",
      "location_count": 1,
      "location_summary": "Toledo, Ohio",
      "locations": [
        {
          "city": "Toledo",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01496456"
    },
    {
      "nct_id": "NCT01111942",
      "title": "A Pilot Study of Induction Chemotherapy Followed by Surgery for Locally Advanced Resectable Head and Neck Cancer",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Head and Neck Cancer"
      ],
      "interventions": [
        {
          "name": "radiation combined with weekly carboplatin",
          "type": "OTHER"
        },
        {
          "name": "conservation surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Southern Illinois University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2010-02",
      "completion_date": "2014-01",
      "has_results": false,
      "last_update_posted_date": "2015-08-05",
      "last_synced_at": "2026-09-20T02:54:11.182Z",
      "location_count": 1,
      "location_summary": "Springfield, Illinois",
      "locations": [
        {
          "city": "Springfield",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01111942"
    },
    {
      "nct_id": "NCT05321719",
      "title": "Multi-Media Parent-based Intervention to Promote Dental Hygiene Among Young Children: BeReady2Smile II",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Plaque"
      ],
      "interventions": [
        {
          "name": "Comparison Condition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "BeReady2Smile video only",
          "type": "BEHAVIORAL"
        },
        {
          "name": "BeReady2Smile video and BeReady2Smile app completely self-guided",
          "type": "BEHAVIORAL"
        },
        {
          "name": "\"Complete\" BeReady2Smile video and BeReady2Smile app guided by a Coach",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Oregon Research Behavioral Intervention Strategies, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 228,
      "start_date": "2023-04-10",
      "completion_date": "2024-04-30",
      "has_results": false,
      "last_update_posted_date": "2025-10-08",
      "last_synced_at": "2026-09-20T02:54:11.182Z",
      "location_count": 1,
      "location_summary": "Springfield, Oregon",
      "locations": [
        {
          "city": "Springfield",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05321719"
    }
  ]
}