{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Oral+water+stimulation",
    "query": {
      "intervention": "Oral water stimulation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Oral+water+stimulation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-16T00:40:18.375Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04786873",
      "title": "A Research Study of How Well Macimorelin Works to Find Out if Children Have a Lack of Growth Hormone and How Safe it is",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Growth Hormone Deficiency"
      ],
      "interventions": [
        {
          "name": "Macimorelin",
          "type": "DRUG"
        },
        {
          "name": "Arginine",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Clonidine",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "AEterna Zentaris",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "2 Years to 17 Years"
      },
      "enrollment_count": 101,
      "start_date": "2021-11-16",
      "completion_date": "2024-06-13",
      "has_results": false,
      "last_update_posted_date": "2024-08-12",
      "last_synced_at": "2026-09-16T00:40:18.375Z",
      "location_count": 12,
      "location_summary": "Tucson, Arizona • Greenwood Village, Colorado • St. Petersburg, Florida + 9 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Greenwood Village",
          "state": "Colorado"
        },
        {
          "city": "St. Petersburg",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Boise",
          "state": "Idaho"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04786873"
    },
    {
      "nct_id": "NCT07049952",
      "title": "BabySTrong II taVNS Feeding Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Feeding Delays",
        "Neonates and Term Infants"
      ],
      "interventions": [
        {
          "name": "taVNS",
          "type": "DEVICE"
        },
        {
          "name": "NAC and taVNS",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "inactive taVNS",
          "type": "DEVICE"
        },
        {
          "name": "sterile water and inactive taVNS",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "39 Weeks",
        "maximum_age": "54 Weeks",
        "sex": "ALL",
        "summary": "39 Weeks to 54 Weeks"
      },
      "enrollment_count": 88,
      "start_date": "2025-11-16",
      "completion_date": "2027-12-30",
      "has_results": false,
      "last_update_posted_date": "2025-11-21",
      "last_synced_at": "2026-09-16T00:40:18.375Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07049952"
    },
    {
      "nct_id": "NCT04749745",
      "title": "Effects of L-theanine on Motor Cortex Excitability in Healthy Subjects: A Paired-Pulse TMS Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Cortical Excitability",
        "Psychiatric Disorder"
      ],
      "interventions": [
        {
          "name": "L-theanine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Butler Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 11,
      "start_date": "2020-06-09",
      "completion_date": "2021-05-31",
      "has_results": true,
      "last_update_posted_date": "2021-09-23",
      "last_synced_at": "2026-09-16T00:40:18.375Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04749745"
    },
    {
      "nct_id": "NCT01977482",
      "title": "Evaluation of Dose Response Relationship, Safety and Efficacy of GSK1278863 in Hemodialysis-dependent Subjects With Chronic Kidney Disease Associated Anemia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anaemia"
      ],
      "interventions": [
        {
          "name": "GSK1278863",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "rhEPO",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 216,
      "start_date": "2013-11-01",
      "completion_date": "2015-02-06",
      "has_results": true,
      "last_update_posted_date": "2018-06-08",
      "last_synced_at": "2026-09-16T00:40:18.375Z",
      "location_count": 17,
      "location_summary": "Azusa, California • Los Angeles, California • San Dimas, California + 13 more",
      "locations": [
        {
          "city": "Azusa",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Dimas",
          "state": "California"
        },
        {
          "city": "West Hills",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01977482"
    },
    {
      "nct_id": "NCT04206540",
      "title": "Effect of Stimulation on the Vagus Nerve",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Subjects"
      ],
      "interventions": [
        {
          "name": "Transcutaneous Auricular Vagus Nerve Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Vagal Stimulation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2019-07-22",
      "completion_date": "2027-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-06",
      "last_synced_at": "2026-09-16T00:40:18.375Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04206540"
    },
    {
      "nct_id": "NCT03844230",
      "title": "Role of Sweetness in Glucose Regulation",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Control - Inhibition",
          "type": "OTHER"
        },
        {
          "name": "Experimental I- Inhibition",
          "type": "OTHER"
        },
        {
          "name": "Experimental II- Inhibition",
          "type": "OTHER"
        },
        {
          "name": "Control- Stimulation",
          "type": "OTHER"
        },
        {
          "name": "Experimental I- Stimulation",
          "type": "OTHER"
        },
        {
          "name": "Experimental II- Stimulation",
          "type": "OTHER"
        },
        {
          "name": "Sensory Evaluation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Illinois at Urbana-Champaign",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "21 Years to 40 Years"
      },
      "enrollment_count": 80,
      "start_date": "2019-04-24",
      "completion_date": "2022-12-31",
      "has_results": false,
      "last_update_posted_date": "2021-04-27",
      "last_synced_at": "2026-09-16T00:40:18.375Z",
      "location_count": 1,
      "location_summary": "Champaign, Illinois",
      "locations": [
        {
          "city": "Champaign",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03844230"
    },
    {
      "nct_id": "NCT01800318",
      "title": "Does Noninvasive Electrical Stimulation of Acupuncture Points (NESAP) Reduce Heelstick Pain in Infants?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "NESAP",
          "type": "DEVICE"
        },
        {
          "name": "24% oral Sucrose",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham NESAP",
          "type": "DEVICE"
        },
        {
          "name": "Oral water",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Arkansas",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "3 Days",
        "sex": "ALL",
        "summary": "1 Day to 3 Days"
      },
      "enrollment_count": 162,
      "start_date": "2013-03",
      "completion_date": "2015-02",
      "has_results": true,
      "last_update_posted_date": "2017-01-16",
      "last_synced_at": "2026-09-16T00:40:18.375Z",
      "location_count": 2,
      "location_summary": "Little Rock, Arkansas • Stanford, California",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01800318"
    },
    {
      "nct_id": "NCT03276481",
      "title": "Prospective Evaluation of Taste Function In Multiple Myeloma Patients Undergoing Autologous Hematopoietic Cell Transplantation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Multiple Myeloma"
      ],
      "interventions": [
        {
          "name": "Oral microbiota assessment",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Comprehensive chemical gustometry",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Measurement of salivary flow",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Surveys assessing taste disturbances",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "BEHAVIORAL"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 47,
      "start_date": "2017-08-28",
      "completion_date": "2023-07-12",
      "has_results": false,
      "last_update_posted_date": "2023-07-14",
      "last_synced_at": "2026-09-16T00:40:18.375Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03276481"
    },
    {
      "nct_id": "NCT00968253",
      "title": "RAD001 Study in Treatment of Relapsed or Refractory Acute Lymphocytic Leukemia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Leukemia",
        "Acute Lymphocytic Leukemia"
      ],
      "interventions": [
        {
          "name": "Everolimus (RAD001)",
          "type": "DRUG"
        },
        {
          "name": "Cyclophosphamide",
          "type": "DRUG"
        },
        {
          "name": "Vincristine",
          "type": "DRUG"
        },
        {
          "name": "Doxorubicin",
          "type": "DRUG"
        },
        {
          "name": "Dexamethasone",
          "type": "DRUG"
        },
        {
          "name": "Mesna",
          "type": "DRUG"
        },
        {
          "name": "Methotrexate",
          "type": "DRUG"
        },
        {
          "name": "Ara-C (Cytarabine)",
          "type": "DRUG"
        },
        {
          "name": "Methylprednisone",
          "type": "DRUG"
        },
        {
          "name": "G-CSF",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "10 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2009-11",
      "completion_date": "2015-12",
      "has_results": true,
      "last_update_posted_date": "2019-02-27",
      "last_synced_at": "2026-09-16T00:40:18.375Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00968253"
    },
    {
      "nct_id": "NCT04100486",
      "title": "Non-Invasive Bioelectronic Analytics",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Autonomic Dysfunction",
        "Autonomic Imbalance",
        "Autonomic Nervous System Diseases",
        "Vagus Nerve Autonomic Disorder"
      ],
      "interventions": [
        {
          "name": "Standing-Squatting-Standing Test",
          "type": "OTHER"
        },
        {
          "name": "Deep Breathing Test",
          "type": "OTHER"
        },
        {
          "name": "Cold Pressor Test",
          "type": "OTHER"
        },
        {
          "name": "Cold Face Test",
          "type": "OTHER"
        },
        {
          "name": "Valsalva Maneuver",
          "type": "OTHER"
        },
        {
          "name": "Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Northwell Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 48,
      "start_date": "2019-08-29",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2026-06-09",
      "last_synced_at": "2026-09-16T00:40:18.375Z",
      "location_count": 1,
      "location_summary": "Manhasset, New York",
      "locations": [
        {
          "city": "Manhasset",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04100486"
    }
  ]
}