{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Orthodontic+Treatment&page=2",
    "query": {
      "intervention": "Orthodontic Treatment",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Orthodontic+Treatment&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-29T10:20:23.645Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01500187",
      "title": "Fluoride Varnish for Treatment of White Spot Lesions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "White Spot Lesions"
      ],
      "interventions": [
        {
          "name": "Vanish Varnish",
          "type": "DEVICE"
        },
        {
          "name": "Pediagel",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Solventum US LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "12 Years to 16 Years"
      },
      "enrollment_count": 38,
      "start_date": "2012-02",
      "completion_date": "2014-03-31",
      "has_results": true,
      "last_update_posted_date": "2024-10-02",
      "last_synced_at": "2026-09-29T10:20:23.645Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01500187"
    },
    {
      "nct_id": "NCT02026258",
      "title": "Efficiency of Piezotome-Corticision Assisted Orthodontics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mandibular Anterior Crowding",
        "Piezocision",
        "Pain Perception"
      ],
      "interventions": [
        {
          "name": "Piezotome-Corticision",
          "type": "PROCEDURE"
        },
        {
          "name": "Orthodontics",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "UConn Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 41,
      "start_date": "2011-12",
      "completion_date": "2016-01",
      "has_results": true,
      "last_update_posted_date": "2017-08-07",
      "last_synced_at": "2026-09-29T10:20:23.645Z",
      "location_count": 1,
      "location_summary": "Farmington, Connecticut",
      "locations": [
        {
          "city": "Farmington",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02026258"
    },
    {
      "nct_id": "NCT03202355",
      "title": "The Effect of OrthoPulse Photobiomodulation on the Rate of Tooth Movement During Alignment With Fixed Appliances",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Malocclusion"
      ],
      "interventions": [
        {
          "name": "Fixed Appliance Orthodontic Treatment",
          "type": "DEVICE"
        },
        {
          "name": "OrthoPulse™",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Biolux Research Holdings, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "11 Years to 60 Years"
      },
      "enrollment_count": 10,
      "start_date": "2017-04-20",
      "completion_date": "2019-03-11",
      "has_results": false,
      "last_update_posted_date": "2019-04-08",
      "last_synced_at": "2026-09-29T10:20:23.645Z",
      "location_count": 3,
      "location_summary": "Chandler, Arizona • Peoria, Arizona • Phoenix, Arizona",
      "locations": [
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Peoria",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03202355"
    },
    {
      "nct_id": "NCT05639907",
      "title": "Miniscrew Stability and Peri-implant Inflammation When Precoated K21 vs Ethanol Control",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Inflammation Caused by the Placement of a Temporary Anchorage Device"
      ],
      "interventions": [
        {
          "name": "K21 Cavity cleanser",
          "type": "DEVICE"
        },
        {
          "name": "Ethanol control",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2022-11-11",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-09-29T10:20:23.645Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05639907"
    },
    {
      "nct_id": "NCT04218331",
      "title": "Boosting Language Outcomes of Minimally Verbal Children With ASD (BLOOM)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autism Spectrum Disorder"
      ],
      "interventions": [
        {
          "name": "JASPER",
          "type": "BEHAVIORAL"
        },
        {
          "name": "PROMPT",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "42 Months",
        "maximum_age": "66 Months",
        "sex": "ALL",
        "summary": "42 Months to 66 Months"
      },
      "enrollment_count": 56,
      "start_date": "2021-04-29",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-23",
      "last_synced_at": "2026-09-29T10:20:23.645Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04218331"
    },
    {
      "nct_id": "NCT04556448",
      "title": "RCT Comparing Invisalign and Traditional Orthodontic Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Malocclusion, Angle Class II"
      ],
      "interventions": [
        {
          "name": "Aligners",
          "type": "OTHER"
        },
        {
          "name": "Clear braces",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Texas A&M University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "17 Years and older"
      },
      "enrollment_count": 78,
      "start_date": "2013-01-01",
      "completion_date": "2019-03-01",
      "has_results": false,
      "last_update_posted_date": "2020-09-21",
      "last_synced_at": "2026-09-29T10:20:23.645Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04556448"
    },
    {
      "nct_id": "NCT02868554",
      "title": "Accelerated Invisalign Therapy in Conjunction With Acceledent Aura",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Malocclusion"
      ],
      "interventions": [
        {
          "name": "AcceleDent Aura",
          "type": "DEVICE"
        },
        {
          "name": "Accelerated Invisalign therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 34,
      "start_date": "2016-08",
      "completion_date": "2019-04-26",
      "has_results": true,
      "last_update_posted_date": "2020-01-27",
      "last_synced_at": "2026-09-29T10:20:23.645Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02868554"
    },
    {
      "nct_id": "NCT03779659",
      "title": "Effectiveness of Synapse Transcutaneous Electronic Nerve Stimulation (TENS) During Dental Procedures Among Children",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Fear",
        "Anesthesia, Local",
        "Pediatric Dentistry"
      ],
      "interventions": [
        {
          "name": "Synapse TENS device",
          "type": "DEVICE"
        },
        {
          "name": "Topical anesthetic gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Boston University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "6 Years to 14 Years"
      },
      "enrollment_count": 0,
      "start_date": "2021-07",
      "completion_date": "2023-02",
      "has_results": false,
      "last_update_posted_date": "2021-06-08",
      "last_synced_at": "2026-09-29T10:20:23.645Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03779659"
    },
    {
      "nct_id": "NCT02267850",
      "title": "Effect of Intra-Oral Photobiomodulation on Orthodontic Treatment Time",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Malocclusion"
      ],
      "interventions": [
        {
          "name": "Fixed Orthodontic Appliance Treatment",
          "type": "OTHER"
        },
        {
          "name": "OrthoPulse™",
          "type": "DEVICE"
        },
        {
          "name": "Non-Functional OrthoPulse™",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Biolux Research Holdings, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "12 Years to 40 Years"
      },
      "enrollment_count": 29,
      "start_date": "2013-05",
      "completion_date": "2016-05",
      "has_results": true,
      "last_update_posted_date": "2018-09-21",
      "last_synced_at": "2026-09-29T10:20:23.645Z",
      "location_count": 1,
      "location_summary": "Suwanee, Georgia",
      "locations": [
        {
          "city": "Suwanee",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02267850"
    },
    {
      "nct_id": "NCT03141788",
      "title": "Evaluation of Clear Aligner Trays to Straighten Teeth",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Malocclusion"
      ],
      "interventions": [
        {
          "name": "Clear Aligner",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Solventum Orthodontics Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "14 Years and older"
      },
      "enrollment_count": 52,
      "start_date": "2017-01-30",
      "completion_date": "2019-10-09",
      "has_results": true,
      "last_update_posted_date": "2024-12-02",
      "last_synced_at": "2026-09-29T10:20:23.645Z",
      "location_count": 9,
      "location_summary": "Denver, Colorado • Kennesaw, Georgia • Catonsville, Maryland + 5 more",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Kennesaw",
          "state": "Georgia"
        },
        {
          "city": "Catonsville",
          "state": "Maryland"
        },
        {
          "city": "Woodbury",
          "state": "Minnesota"
        },
        {
          "city": "Woodbury",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03141788"
    }
  ]
}