{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Oscillatory+Positive+Expiratory+Pressure",
    "query": {
      "intervention": "Oscillatory Positive Expiratory Pressure"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-21T19:46:06.502Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05388708",
      "title": "ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment (ASCEND)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Respiratory Distress Syndrome",
        "Extracorporeal Membrane Oxygenation"
      ],
      "interventions": [
        {
          "name": "ECMO support",
          "type": "DEVICE"
        },
        {
          "name": "PROSpect protocolized therapies",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Days",
        "maximum_age": "20 Years",
        "sex": "ALL",
        "summary": "14 Days to 20 Years"
      },
      "enrollment_count": 550,
      "start_date": "2021-02-04",
      "completion_date": "2027-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-14",
      "last_synced_at": "2026-09-21T19:46:06.502Z",
      "location_count": 72,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 62 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05388708"
    },
    {
      "nct_id": "NCT04540510",
      "title": "OPEP Devices in Acute Inpatient Treatment of Pneumonia",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Community-acquired Pneumonia"
      ],
      "interventions": [
        {
          "name": "OPEP therapy",
          "type": "DEVICE"
        },
        {
          "name": "Standard care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Danbury Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 11,
      "start_date": "2019-08-13",
      "completion_date": "2021-02-18",
      "has_results": true,
      "last_update_posted_date": "2021-09-24",
      "last_synced_at": "2026-09-21T19:46:06.502Z",
      "location_count": 1,
      "location_summary": "Norwalk, Connecticut",
      "locations": [
        {
          "city": "Norwalk",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04540510"
    },
    {
      "nct_id": "NCT05873504",
      "title": "Outcome Comparisons of Vibratory Airway Clearance Devices",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Airway Clearance Impairment"
      ],
      "interventions": [
        {
          "name": "High Oscillatory Index Device",
          "type": "DEVICE"
        },
        {
          "name": "Low Oscillatory Index Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 64,
      "start_date": "2023-05-01",
      "completion_date": "2026-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-19",
      "last_synced_at": "2026-09-21T19:46:06.502Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05873504"
    },
    {
      "nct_id": "NCT00839644",
      "title": "Airway Secretion Clearance in Cystic Fibrosis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cystic Fibrosis"
      ],
      "interventions": [
        {
          "name": "High frequency chest wall oscillation",
          "type": "DEVICE"
        },
        {
          "name": "Oscillatory Positive Expiratory Pressure",
          "type": "DEVICE"
        },
        {
          "name": "PD&P: Postural drainage and percussion",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "7 Years and older"
      },
      "enrollment_count": 166,
      "start_date": "1999-12",
      "completion_date": "2003-06",
      "has_results": false,
      "last_update_posted_date": "2012-10-02",
      "last_synced_at": "2026-09-21T19:46:06.502Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00839644"
    },
    {
      "nct_id": "NCT03078127",
      "title": "Researching the Effects of Airway Clearance Therapies in Cystic Fibrosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cystic Fibrosis",
        "Mucociliary Clearance Defect"
      ],
      "interventions": [
        {
          "name": "Baseline (Huff-Cough alone)",
          "type": "OTHER"
        },
        {
          "name": "Oscillatory Positive Expiatory Pressure Device",
          "type": "DEVICE"
        },
        {
          "name": "Whole-Body Vibration Platform",
          "type": "DEVICE"
        },
        {
          "name": "High Frequency Chest Wall Oscillatory Vest",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2017-02-01",
      "completion_date": "2018-01-10",
      "has_results": true,
      "last_update_posted_date": "2019-03-05",
      "last_synced_at": "2026-09-21T19:46:06.502Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03078127"
    },
    {
      "nct_id": "NCT04774848",
      "title": "High Frequency Oscillatory Ventilation Versus High Frequency Jet Ventilation for Congenital Diaphragmatic Hernia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Congenital Diaphragmatic Hernia"
      ],
      "interventions": [
        {
          "name": "High Frequency Jet Ventilator",
          "type": "DEVICE"
        },
        {
          "name": "High Frequency Oscillatory Ventilator",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "Up to 24 Hours"
      },
      "enrollment_count": 50,
      "start_date": "2020-12-30",
      "completion_date": "2025-08-28",
      "has_results": false,
      "last_update_posted_date": "2025-04-04",
      "last_synced_at": "2026-09-21T19:46:06.502Z",
      "location_count": 2,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04774848"
    }
  ]
}