{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Oxygen+21+%25&page=5", "query": { "intervention": "Oxygen 21 %", "page": 5 }, "page_size": 10 }, "pagination": { "page": 5, "page_size": 10, "total_count": 99, "total_pages": 10, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Oxygen+21+%25&page=6&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Oxygen+21+%25&page=4&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-09T06:35:16.645Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04626791", "title": "Modified VR-CAP and Acalabrutinib as First Line Therapy for the Treatment of Transplant-Eligible Patients With Mantle Cell Lymphoma", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Mantle Cell Lymphoma" ], "interventions": [ { "name": "Acalabrutinib", "type": "DRUG" }, { "name": "Bortezomib", "type": "DRUG" }, { "name": "Cyclophosphamide", "type": "DRUG" }, { "name": "Cytarabine", "type": "DRUG" }, { "name": "Doxorubicin Hydrochloride", "type": "DRUG" }, { "name": "Prednisone", "type": "DRUG" }, { "name": "Rituximab", "type": "BIOLOGICAL" }, { "name": "Rituximab and Hyaluronidase Human", "type": "BIOLOGICAL" } ], "intervention_types": [ "DRUG", "BIOLOGICAL" ], "sponsor": "Academic and Community Cancer Research United", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 41, "start_date": "2021-08-03", "completion_date": "2028-08-03", "has_results": true, "last_update_posted_date": "2026-08-25", "last_synced_at": "2026-10-09T06:35:16.645Z", "location_count": 3, "location_summary": "New York, New York • Charlotte, North Carolina • Seattle, Washington", "locations": [ { "city": "New York", "state": "New York" }, { "city": "Charlotte", "state": "North Carolina" }, { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT04626791" }, { "nct_id": "NCT04280484", "title": "Acute Intermittent Hypoxia in Persons With Multiple Sclerosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Multiple Sclerosis, Relapsing-Remitting" ], "interventions": [ { "name": "Intermittent Hypoxia", "type": "OTHER" }, { "name": "Sham Hypoxia", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Shirley Ryan AbilityLab", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 10, "start_date": "2018-06-18", "completion_date": "2019-12-30", "has_results": false, "last_update_posted_date": "2020-02-24", "last_synced_at": "2026-10-09T06:35:16.645Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT04280484" }, { "nct_id": "NCT02473354", "title": "Predictors of Opioid-Induced Respiratory Depression (OIRD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Respiratory Depression" ], "interventions": [ { "name": "Remifentanil", "type": "DRUG" }, { "name": "Oxygen", "type": "DRUG" }, { "name": "Carbon dioxide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 30, "start_date": "2015-04", "completion_date": "2018-04-29", "has_results": false, "last_update_posted_date": "2020-03-10", "last_synced_at": "2026-10-09T06:35:16.645Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02473354" }, { "nct_id": "NCT07605416", "title": "Testing an Experimental Approach to Treat Patients With Plasma Cell Leukemia, The QUANTUM Trial", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Plasma Cell Leukemia" ], "interventions": [ { "name": "Autologous Hematopoietic Stem Cell Transplantation", "type": "PROCEDURE" }, { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Bone Marrow Aspiration", "type": "PROCEDURE" }, { "name": "Bone Marrow Biopsy", "type": "PROCEDURE" }, { "name": "Carfilzomib", "type": "DRUG" }, { "name": "Computed Tomography", "type": "PROCEDURE" }, { "name": "Daratumumab and Recombinant Human Hyaluronidase", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" }, { "name": "Fludeoxyglucose F-18", "type": "OTHER" }, { "name": "Lenalidomide", "type": "DRUG" }, { "name": "Magnetic Resonance Imaging", "type": "PROCEDURE" }, { "name": "Melphalan", "type": "DRUG" }, { "name": "Plerixafor", "type": "DRUG" }, { "name": "Positron Emission Tomography", "type": "PROCEDURE" }, { "name": "Recombinant Granulocyte Colony-Stimulating Factor", "type": "BIOLOGICAL" }, { "name": "Stem Cell Isolation", "type": "PROCEDURE" }, { "name": "Teclistamab", "type": "DRUG" }, { "name": "Transthoracic Echocardiography Test", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE", "DRUG", "OTHER", "BIOLOGICAL" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 74, "start_date": "2027-04-20", "completion_date": "2032-11-06", "has_results": false, "last_update_posted_date": "2026-10-07", "last_synced_at": "2026-10-09T06:35:16.645Z", "location_count": 10, "location_summary": "New Haven, Connecticut • North Haven, Connecticut • Baton Rouge, Louisiana + 7 more", "locations": [ { "city": "New Haven", "state": "Connecticut" }, { "city": "North Haven", "state": "Connecticut" }, { "city": "Baton Rouge", "state": "Louisiana" }, { "city": "Middletown", "state": "New Jersey" }, { "city": "Montvale", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT07605416" }, { "nct_id": "NCT01751971", "title": "Estimating Apnea Phenotypes From Polysomnography: Oxygen", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Sleep Apnea" ], "interventions": [ { "name": "Inspired oxygen (40%)", "type": "DRUG" }, { "name": "Sham", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "20 Years", "maximum_age": "79 Years", "sex": "ALL", "summary": "20 Years to 79 Years" }, "enrollment_count": 47, "start_date": "2012-11", "completion_date": "2016-07", "has_results": true, "last_update_posted_date": "2018-03-20", "last_synced_at": "2026-10-09T06:35:16.645Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01751971" }, { "nct_id": "NCT06390930", "title": "Effects of Acute Intermittent Hypoxia on Neuroplasticity in MS", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Multiple Sclerosis", "Multiple Sclerosis, Relapsing-Remitting", "Multiple Sclerosis, Secondary Progressive" ], "interventions": [ { "name": "Acute Intermittent Hypoxia", "type": "OTHER" }, { "name": "Sham Acute Intermittent Hypoxia", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Shirley Ryan AbilityLab", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 22, "start_date": "2025-02-01", "completion_date": "2027-07", "has_results": false, "last_update_posted_date": "2026-02-23", "last_synced_at": "2026-10-09T06:35:16.645Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT06390930" }, { "nct_id": "NCT02300064", "title": "Exercise in Health and Chronic Obstructive Pulmonary Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Chronic Obstructive Pulmonary Disease" ], "interventions": [ { "name": "Knee-extensor exercise test", "type": "OTHER" }, { "name": "Exercise test with restricting/releasing blood flow", "type": "OTHER" }, { "name": "Exercise test with variable oxygen concentration and MRI", "type": "OTHER" }, { "name": "Exercise test with oral antioxidant or placebo cocktail", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Utah", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 185, "start_date": "2009-01", "completion_date": "2016-05", "has_results": false, "last_update_posted_date": "2016-06-01", "last_synced_at": "2026-10-09T06:35:16.645Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT02300064" }, { "nct_id": "NCT05464329", "title": "Mosunetuzumab in Combination With Platinum-Based Salvage Chemotherapy in Patients With Relapsed/Refractory Aggressive B Cell Lymphoma", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Large B-cell Lymphoma", "High-grade B-cell Lymphoma", "Transformed B-Cell Lymphoma", "Follicular Lymphoma Grade 3B" ], "interventions": [ { "name": "Mosunetuzumab", "type": "DRUG" }, { "name": "DHAX", "type": "DRUG" }, { "name": "ICE", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 24, "start_date": "2023-01-03", "completion_date": "2029-10-16", "has_results": false, "last_update_posted_date": "2026-01-08", "last_synced_at": "2026-10-09T06:35:16.645Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT05464329" }, { "nct_id": "NCT03315065", "title": "19F Thoracic Radiotherapy for Lung Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Lung Cancer" ], "interventions": [ { "name": "Perfluorinated Gas/Oxygen Mixture", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Hal C Charles", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 6, "start_date": "2018-02-16", "completion_date": "2019-06-25", "has_results": false, "last_update_posted_date": "2019-07-16", "last_synced_at": "2026-10-09T06:35:16.645Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03315065" }, { "nct_id": "NCT04801810", "title": "Daily Low Oxygen Exposure and Weight Status", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Overweight and Obesity" ], "interventions": [ { "name": "Normobaric hypoxia", "type": "OTHER" }, { "name": "Normobaric normoxia", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Florida State University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "20 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "20 Years to 50 Years" }, "enrollment_count": 0, "start_date": "2022-05", "completion_date": "2023-05", "has_results": false, "last_update_posted_date": "2022-04-01", "last_synced_at": "2026-10-09T06:35:16.645Z", "location_count": 1, "location_summary": "Tallahassee, Florida", "locations": [ { "city": "Tallahassee", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04801810" } ] }