{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PBI-200",
    "query": {
      "intervention": "PBI-200"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 5,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-13T03:10:36.978Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05690932",
      "title": "A Formulation Bridging and Food Effect Study of PBI-200 in Healthy Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Formulation Bridging",
        "Food Effect"
      ],
      "interventions": [
        {
          "name": "PBI-200 Tablet",
          "type": "DRUG"
        },
        {
          "name": "PBI-200 Capsule",
          "type": "DRUG"
        },
        {
          "name": "PBI-200 Suspension",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pyramid Biosciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 33,
      "start_date": "2022-02-24",
      "completion_date": "2022-05-23",
      "has_results": false,
      "last_update_posted_date": "2023-02-01",
      "last_synced_at": "2026-09-13T03:10:36.978Z",
      "location_count": 1,
      "location_summary": "Springfield, Missouri",
      "locations": [
        {
          "city": "Springfield",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05690932"
    },
    {
      "nct_id": "NCT05160389",
      "title": "A Study to Assess the Effect of Food on the Absorption and Bioavailability of PBI-200",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Food Effect in Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "PBI-200",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pyramid Biosciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 16,
      "start_date": "2021-11-17",
      "completion_date": "2022-01-06",
      "has_results": false,
      "last_update_posted_date": "2022-01-27",
      "last_synced_at": "2026-09-13T03:10:36.978Z",
      "location_count": 1,
      "location_summary": "Springfield, Missouri",
      "locations": [
        {
          "city": "Springfield",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05160389"
    },
    {
      "nct_id": "NCT05238337",
      "title": "A Phase 1 Study of the Absorption, Metabolism, and Excretion of [14C] PBI-200",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Absorption, Metabolism and Excretion in Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "[14C]-PBI-200",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pyramid Biosciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "MALE",
        "summary": "18 Years to 65 Years · Male only"
      },
      "enrollment_count": 6,
      "start_date": "2022-02-24",
      "completion_date": "2022-03-24",
      "has_results": false,
      "last_update_posted_date": "2022-08-30",
      "last_synced_at": "2026-09-13T03:10:36.978Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05238337"
    },
    {
      "nct_id": "NCT05692570",
      "title": "A Study of PBI-200 With Ritonavir or Cobicistat in Healthy Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Drug-drug Interaction"
      ],
      "interventions": [
        {
          "name": "PBI-200 Tablet",
          "type": "DRUG"
        },
        {
          "name": "Ritonavir Oral Tablet",
          "type": "DRUG"
        },
        {
          "name": "Cobicistat Oral Tablet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pyramid Biosciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 21,
      "start_date": "2022-09-09",
      "completion_date": "2022-11-12",
      "has_results": false,
      "last_update_posted_date": "2023-01-20",
      "last_synced_at": "2026-09-13T03:10:36.978Z",
      "location_count": 1,
      "location_summary": "Tempe, Arizona",
      "locations": [
        {
          "city": "Tempe",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05692570"
    },
    {
      "nct_id": "NCT04901806",
      "title": "Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Solid Tumor, Adult",
        "Brain Tumor, Primary",
        "Desmoplastic Small Round Cell Tumor"
      ],
      "interventions": [
        {
          "name": "PBI-200",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pyramid Biosciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 29,
      "start_date": "2021-07-20",
      "completion_date": "2023-07-26",
      "has_results": false,
      "last_update_posted_date": "2024-03-28",
      "last_synced_at": "2026-09-13T03:10:36.978Z",
      "location_count": 11,
      "location_summary": "Santa Monica, California • Stanford, California • Denver, Colorado + 7 more",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Lake Mary",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04901806"
    }
  ]
}