{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PBM+Therapy",
    "query": {
      "intervention": "PBM Therapy"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 109,
    "total_pages": 11,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PBM+Therapy&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-06T20:18:30.235Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06708754",
      "title": "Impact of Photobiomodulation (PBM) on Biomarkers of Radiation Lymphedema and Fibrosis in Head and Neck Cancer Patients",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Radiation Lymphedema",
        "Radiation Fibrosis",
        "Head and Neck Cancer"
      ],
      "interventions": [
        {
          "name": "Photobiomodulation (PBM) Therapy",
          "type": "DEVICE"
        },
        {
          "name": "Sham PBM",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2025-02-13",
      "completion_date": "2030-02-13",
      "has_results": false,
      "last_update_posted_date": "2026-03-30",
      "last_synced_at": "2026-09-06T20:18:30.235Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06708754"
    },
    {
      "nct_id": "NCT03209882",
      "title": "Transcranial Infrared Laser Stimulation (TILS) of Prefrontal Cognition in Post-traumatic Stress Disorder (PTSD)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-traumatic Stress Disorder (PTSD)"
      ],
      "interventions": [
        {
          "name": "TILS",
          "type": "DEVICE"
        },
        {
          "name": "sham",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas at Arlington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 10,
      "start_date": "2017-10-01",
      "completion_date": "2019-10-08",
      "has_results": true,
      "last_update_posted_date": "2021-07-23",
      "last_synced_at": "2026-09-06T20:18:30.235Z",
      "location_count": 1,
      "location_summary": "Arlington, Texas",
      "locations": [
        {
          "city": "Arlington",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03209882"
    },
    {
      "nct_id": "NCT03844672",
      "title": "Impact of E-cigarette Characteristics on Reinforcement and Tobacco Use Patterns",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "Low Power",
          "type": "BEHAVIORAL"
        },
        {
          "name": "High Power",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Low Concentration",
          "type": "BEHAVIORAL"
        },
        {
          "name": "High Concentration",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 93,
      "start_date": "2019-04-01",
      "completion_date": "2023-11-09",
      "has_results": true,
      "last_update_posted_date": "2024-10-24",
      "last_synced_at": "2026-09-06T20:18:30.235Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03844672"
    },
    {
      "nct_id": "NCT03972527",
      "title": "Photobiomodulation to Demonstrate Safety and Reduce the Incidence of Oral Mucositis in Adult Head & Neck Cancer Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Oral Mucositis (Ulcerative)",
        "Oral Mucositis (Ulcerative) Due to Radiation",
        "Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy",
        "Head and Neck Cancer"
      ],
      "interventions": [
        {
          "name": "Photobiomodulation",
          "type": "DEVICE"
        },
        {
          "name": "Routine Oral Care and Analgesia",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "MuReva Phototherapy Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 85,
      "start_date": "2022-08-05",
      "completion_date": "2024-07-18",
      "has_results": false,
      "last_update_posted_date": "2024-08-21",
      "last_synced_at": "2026-09-06T20:18:30.235Z",
      "location_count": 12,
      "location_summary": "Birmingham, Alabama • Long Beach, California • Miami, Florida + 9 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Edgewood",
          "state": "Kentucky"
        },
        {
          "city": "Shreveport",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03972527"
    },
    {
      "nct_id": "NCT00961454",
      "title": "Photobiomodulation to Alter Cerebral Blood Flow and to Affect the Emotional Status of Patients With Major Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Major Depression",
        "Anxiety Disorder",
        "Post-Traumatic Stress Disorder",
        "Substance Abuse Disorder"
      ],
      "interventions": [
        {
          "name": "Photobiomodulation with a super-luminous light emitting diode",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 10,
      "start_date": "2009-01",
      "completion_date": "2009-06",
      "has_results": false,
      "last_update_posted_date": "2009-08-19",
      "last_synced_at": "2026-09-06T20:18:30.235Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00961454"
    },
    {
      "nct_id": "NCT05083442",
      "title": "Low-level Laser and Lifestyle Modifications",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overweight and Obesity",
        "Weight Loss"
      ],
      "interventions": [
        {
          "name": "Low Level Laser Therapy",
          "type": "DEVICE"
        },
        {
          "name": "Sham (placebo)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2022-06-01",
      "completion_date": "2024-12-30",
      "has_results": true,
      "last_update_posted_date": "2025-04-03",
      "last_synced_at": "2026-09-06T20:18:30.235Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05083442"
    },
    {
      "nct_id": "NCT06623305",
      "title": "A Clinical Trial of the Administration of Light Therapy to Prevent Mouth Sores in Children With Cancer",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mucositis Oral"
      ],
      "interventions": [
        {
          "name": "Photobiomodulation for prevention arm",
          "type": "DEVICE"
        },
        {
          "name": "Photobiomodulation for exploratory arm",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "Up to 30 Years"
      },
      "enrollment_count": 50,
      "start_date": "2026-08",
      "completion_date": "2027-09",
      "has_results": false,
      "last_update_posted_date": "2026-06-22",
      "last_synced_at": "2026-09-06T20:18:30.235Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06623305"
    },
    {
      "nct_id": "NCT05298956",
      "title": "Brain Substrates for Cardiovascular Stress Physiology",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress Reaction"
      ],
      "interventions": [
        {
          "name": "Low-level laser therapy (LLLT)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Baylor University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 40,
      "start_date": "2022-03-14",
      "completion_date": "2024-08",
      "has_results": false,
      "last_update_posted_date": "2023-08-01",
      "last_synced_at": "2026-09-06T20:18:30.235Z",
      "location_count": 1,
      "location_summary": "Waco, Texas",
      "locations": [
        {
          "city": "Waco",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05298956"
    },
    {
      "nct_id": "NCT01006408",
      "title": "Treatment Trial Using Low Level Laser Therapy (LLLT) for Treatment of Chemotherapy Induced Peripheral Neuropathy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Peripheral Neuropathy"
      ],
      "interventions": [
        {
          "name": "Low Level Laser",
          "type": "PROCEDURE"
        },
        {
          "name": "Placebo followed by Low Level Laser",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Legacy Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2009-10",
      "completion_date": "2010-11",
      "has_results": false,
      "last_update_posted_date": "2012-10-19",
      "last_synced_at": "2026-09-06T20:18:30.235Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01006408"
    },
    {
      "nct_id": "NCT01820416",
      "title": "The Effect of Low-Level Laser Stimulation on Hearing Thresholds",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hearing Loss"
      ],
      "interventions": [
        {
          "name": "Low-level Laser Therapy",
          "type": "RADIATION"
        },
        {
          "name": "Placebo Comparator: Disabled Laser",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "RADIATION",
        "OTHER"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 35,
      "start_date": "2009-09",
      "completion_date": "2009-12",
      "has_results": true,
      "last_update_posted_date": "2017-06-01",
      "last_synced_at": "2026-09-06T20:18:30.235Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01820416"
    }
  ]
}