{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PEEPS", "query": { "intervention": "PEEPS" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 66, "total_pages": 7, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PEEPS&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-10T06:08:37.280Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06518239", "title": "Establishing Optimal PEEP Setting for Obese Patients in the Steep Trendelenburg Position", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Obesity" ], "interventions": [ { "name": "Peep Belt", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of Missouri-Columbia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "19 Years", "maximum_age": null, "sex": "ALL", "summary": "19 Years and older" }, "enrollment_count": 30, "start_date": "2024-11-18", "completion_date": "2026-03-30", "has_results": false, "last_update_posted_date": "2026-06-11", "last_synced_at": "2026-09-10T06:08:37.280Z", "location_count": 1, "location_summary": "Columbia, Missouri", "locations": [ { "city": "Columbia", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT06518239" }, { "nct_id": "NCT04108130", "title": "An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Postoperative Pulmonary Complications" ], "interventions": [ { "name": "Preoperative Education", "type": "OTHER" }, { "name": "Intraoperative PEEP (Positive End-Expiratory Pressure) Individualization", "type": "PROCEDURE" }, { "name": "Individualization of Neuromuscular Blockade", "type": "OTHER" }, { "name": "Postoperative Incentive Spirometry", "type": "PROCEDURE" }, { "name": "Postoperative Ambulation", "type": "BEHAVIORAL" } ], "intervention_types": [ "OTHER", "PROCEDURE", "BEHAVIORAL" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 794, "start_date": "2020-01-29", "completion_date": "2023-07-13", "has_results": true, "last_update_posted_date": "2025-10-06", "last_synced_at": "2026-09-10T06:08:37.280Z", "location_count": 16, "location_summary": "San Francisco, California • Stanford, California • Aurora, Colorado + 10 more", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Stanford", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Miami", "state": "Florida" }, { "city": "Evanston", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT04108130" }, { "nct_id": "NCT05440851", "title": "Platform of Randomized Adaptive Clinical Trials in Critical Illness", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Respiratory Insufficiency", "Extracorporeal Membrane Oxygenation Complication", "Mechanical Ventilation Pressure High" ], "interventions": [ { "name": "Ultra-Protective Ventilation Facilitated by Extracorporeal Support", "type": "OTHER" }, { "name": "Lung-Protective Ventilation (LPV)", "type": "OTHER" }, { "name": "Driving Pressure-Limited Ventilation (DPL)", "type": "OTHER" }, { "name": "Lung- and Diaphragm-Protective Ventilation and Sedation (LDPVS)", "type": "OTHER" }, { "name": "Early Cohort corticosteroid dose", "type": "DRUG" }, { "name": "Extended Cohort corticosteroid dose", "type": "DRUG" }, { "name": "Usual care without routine corticosteroids", "type": "DRUG" }, { "name": "Usual care without extending corticosteroids", "type": "DRUG" }, { "name": "Usual care with fludrocortisone", "type": "DRUG" }, { "name": "Usual care without fludrocortisone", "type": "DRUG" }, { "name": "Drug 4 mL:", "type": "DRUG" }, { "name": "Drug 40 mg:", "type": "DRUG" }, { "name": "PEEP-20", "type": "OTHER" }, { "name": "PEEP-AOP", "type": "OTHER" }, { "name": "PEEP-10", "type": "OTHER" }, { "name": "VV ECMO-facilitated strategy of earlier awakening, extubation and rehabilitation", "type": "OTHER" }, { "name": "Electrical impedance tomography (EIT)", "type": "OTHER" }, { "name": "no treatment / intervention arm is involved.", "type": "OTHER" }, { "name": "Usual care", "type": "OTHER" }, { "name": "Early Routine IMT", "type": "OTHER" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "University Health Network, Toronto", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 6250, "start_date": "2023-04-30", "completion_date": "2027-03-31", "has_results": false, "last_update_posted_date": "2026-05-07", "last_synced_at": "2026-09-10T06:08:37.280Z", "location_count": 26, "location_summary": "Tucson, Arizona • Los Angeles, California • San Diego, California + 19 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT05440851" }, { "nct_id": "NCT05530434", "title": "Transpulmonary Pressure Guided Mechanical Ventilation Weaning in Obesity", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Respiratory Failure", "Obesity" ], "interventions": [ { "name": "transpulmonary pressure guided positive end expiratory pressure", "type": "OTHER" }, { "name": "standard positive end expiratory pressure", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Mississippi Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 4, "start_date": "2022-04-11", "completion_date": "2026-04-14", "has_results": false, "last_update_posted_date": "2026-05-14", "last_synced_at": "2026-09-10T06:08:37.280Z", "location_count": 1, "location_summary": "Jackson, Mississippi", "locations": [ { "city": "Jackson", "state": "Mississippi" } ], "official_url": "https://clinicaltrials.gov/study/NCT05530434" }, { "nct_id": "NCT02139800", "title": "Sustained Aeration of Infant Lungs Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Preterm Birth", "Extreme Prematurity" ], "interventions": [ { "name": "Sustained Inflation", "type": "PROCEDURE" }, { "name": "Standard of Care", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "23 Weeks", "maximum_age": "26 Weeks", "sex": "ALL", "summary": "23 Weeks to 26 Weeks" }, "enrollment_count": 460, "start_date": "2014-08-27", "completion_date": "2020-03-23", "has_results": true, "last_update_posted_date": "2023-04-06", "last_synced_at": "2026-09-10T06:08:37.280Z", "location_count": 9, "location_summary": "Loma Linda, California • Sacramento, California • San Diego, California + 5 more", "locations": [ { "city": "Loma Linda", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Newark", "state": "Delaware" }, { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT02139800" }, { "nct_id": "NCT07531602", "title": "Effect of PEEP on Cardiac Function", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cardiac Surgery Subjects" ], "interventions": [ { "name": "EIT Guided PEEP Trial", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Beth Israel Deaconess Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 28, "start_date": "2026-06-17", "completion_date": "2028-10-30", "has_results": false, "last_update_posted_date": "2026-07-01", "last_synced_at": "2026-09-10T06:08:37.280Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT07531602" }, { "nct_id": "NCT02492113", "title": "Effects of Different PEEP Levels on Work of Breathing in Morbidly Obese Patients Prior to and After Extubation", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Obesity" ], "interventions": [ { "name": "Positive end-expiratory pressure (PEEP)", "type": "PROCEDURE" }, { "name": "ZEEP", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2015-11", "completion_date": "2025-11-24", "has_results": false, "last_update_posted_date": "2026-02-20", "last_synced_at": "2026-09-10T06:08:37.280Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02492113" }, { "nct_id": "NCT07019987", "title": "Adiposity Distribution in Acute Respiratory Failure", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Acute Hypoxemic Respiratory Failure", "Obesity" ], "interventions": [ { "name": "PEEP Titration Using Electrical Impedance Tomography (EIT)", "type": "OTHER" }, { "name": "Body Positioning: Supine and Prone", "type": "PROCEDURE" } ], "intervention_types": [ "OTHER", "PROCEDURE" ], "sponsor": "Maurizio F. Cereda, MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 80, "start_date": "2028-01-01", "completion_date": "2030-06-30", "has_results": false, "last_update_posted_date": "2025-06-13", "last_synced_at": "2026-09-10T06:08:37.280Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT07019987" }, { "nct_id": "NCT01681225", "title": "EPVent 2- A Phase II Study of Mechanical Ventilation Directed by Transpulmonary Pressures", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Acute Respiratory Distress Syndrome" ], "interventions": [ { "name": "Esophageal-pressure guided mechanical ventilation", "type": "OTHER" }, { "name": "High PEEP mechanical ventilation", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Beth Israel Deaconess Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": null, "sex": "ALL", "summary": "16 Years and older" }, "enrollment_count": 202, "start_date": "2012-10-31", "completion_date": "2018-10-19", "has_results": false, "last_update_posted_date": "2019-12-03", "last_synced_at": "2026-09-10T06:08:37.280Z", "location_count": 10, "location_summary": "La Jolla, California • Stanford, California • Orlando, Florida + 6 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Stanford", "state": "California" }, { "city": "Orlando", "state": "Florida" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01681225" }, { "nct_id": "NCT00446706", "title": "Estimation of Intrinsic Positive End-Expiratory Pressure (PEEP) in Acute Respiratory Distress Syndrome (ARDS)", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Acute Respiratory Distress Syndrome" ], "interventions": [], "intervention_types": [], "sponsor": "Texas Tech University Health Sciences Center, El Paso", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 6, "start_date": "2004-01", "completion_date": "2007-04", "has_results": false, "last_update_posted_date": "2017-05-09", "last_synced_at": "2026-09-10T06:08:37.280Z", "location_count": 1, "location_summary": "El Paso, Texas", "locations": [ { "city": "El Paso", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00446706" } ] }