{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PF-05221304", "query": { "intervention": "PF-05221304" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 8, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-13T01:30:25.138Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02871037", "title": "Single Dose, Repeated Dose, and Conditional Food Effect Study of PF-05221304 in Healthy Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Normal Healthy" ], "interventions": [ { "name": "PF-05221304", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 96, "start_date": "2016-08", "completion_date": "2017-03", "has_results": false, "last_update_posted_date": "2018-05-24", "last_synced_at": "2026-09-13T01:30:25.138Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT02871037" }, { "nct_id": "NCT04321031", "title": "Metabolic Interventions to Resolve Non-alcoholic Steatohepatitis (NASH) With Fibrosis (MIRNA)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Nonalcoholic Fatty Liver Disease", "Nonalcoholic Steatohepatitis With Liver Fibrosis" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "PF-06865571", "type": "DRUG" }, { "name": "PF-05221304", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 256, "start_date": "2020-06-15", "completion_date": "2024-02-21", "has_results": true, "last_update_posted_date": "2025-03-21", "last_synced_at": "2026-09-13T01:30:25.138Z", "location_count": 184, "location_summary": "Chandler, Arizona • Gilbert, Arizona • Glendale, Arizona + 101 more", "locations": [ { "city": "Chandler", "state": "Arizona" }, { "city": "Gilbert", "state": "Arizona" }, { "city": "Glendale", "state": "Arizona" }, { "city": "Peoria", "state": "Arizona" }, { "city": "Sun City", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT04321031" }, { "nct_id": "NCT03871439", "title": "OPEN LABEL, 2-PERIOD STUDY, TO COMPARE BIO-AVAILABILITY OF 2 DIFFERENT FORMULATIONS OF PF-05221304 IN HEALTHY ADULTS", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "PF-05221304 Formulation A", "type": "DRUG" }, { "name": "PF-05221304 Formulation B", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 10, "start_date": "2019-03-13", "completion_date": "2019-05-08", "has_results": false, "last_update_posted_date": "2020-05-20", "last_synced_at": "2026-09-13T01:30:25.138Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT03871439" }, { "nct_id": "NCT03248882", "title": "Phase 2a, Dose-ranging Study With PF-05221304 in Nonalcoholic Fatty Liver Disease (NAFLD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Nonalcoholic Fatty Liver Disease", "Nonalcoholic Steatohepatitis" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "PF-05221304", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 305, "start_date": "2017-08-22", "completion_date": "2019-03-27", "has_results": true, "last_update_posted_date": "2020-12-09", "last_synced_at": "2026-09-13T01:30:25.138Z", "location_count": 60, "location_summary": "Bakersfield, California • Chula Vista, California • La Jolla, California + 43 more", "locations": [ { "city": "Bakersfield", "state": "California" }, { "city": "Chula Vista", "state": "California" }, { "city": "Chula Vista", "state": "California" }, { "city": "La Jolla", "state": "California" }, { "city": "La Jolla", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03248882" }, { "nct_id": "NCT03448172", "title": "Single-dose Study of [14C]PF-05221304 Metabolism and Excretion in Healthy Adult Male Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "[14C]PF-05221304", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "MALE", "summary": "18 Years to 45 Years · Male only" }, "enrollment_count": 6, "start_date": "2018-04-18", "completion_date": "2018-06-13", "has_results": false, "last_update_posted_date": "2018-12-04", "last_synced_at": "2026-09-13T01:30:25.138Z", "location_count": 1, "location_summary": "Madison, Wisconsin", "locations": [ { "city": "Madison", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT03448172" }, { "nct_id": "NCT03309202", "title": "Study of PF-05221304 in Subjects With Varying Degrees of Hepatic Impairment", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Hepatic Impairment" ], "interventions": [ { "name": "PF-05221304", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 24, "start_date": "2017-12-19", "completion_date": "2018-07-18", "has_results": true, "last_update_posted_date": "2019-08-08", "last_synced_at": "2026-09-13T01:30:25.138Z", "location_count": 1, "location_summary": "Orlando, Florida", "locations": [ { "city": "Orlando", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03309202" }, { "nct_id": "NCT03776175", "title": "A Study To Assess Pharmacodynamics, Safety And Tolerability Of PF-05221304 And PF-06865571 Co-Administered For 6 Weeks In Adults With Non-Alcoholic Fatty Liver Disease.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Non-Alcoholic Fatty Liver Disease (NAFLD)" ], "interventions": [ { "name": "PF-05221304 Monotherapy", "type": "DRUG" }, { "name": "PF-06865571 Monotherapy", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "PF-05221304 and PF-06865571 Combination", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 99, "start_date": "2019-01-04", "completion_date": "2019-10-11", "has_results": true, "last_update_posted_date": "2020-09-23", "last_synced_at": "2026-09-13T01:30:25.138Z", "location_count": 29, "location_summary": "Bakersfield, California • Beverly Hills, California • Chula Vista, California + 22 more", "locations": [ { "city": "Bakersfield", "state": "California" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Chula Vista", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Montclair", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03776175" }, { "nct_id": "NCT04399538", "title": "Study of Pharmacodynamics and Safety of DGAT2i and ACCi Coadministered in Participants With Sponsor-defined Presumed Non Alcoholic Steatohepatitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Nonalcoholic Steatohepatitis", "Nonalcoholic Fatty Liver Disease" ], "interventions": [ { "name": "PF-06865571", "type": "DRUG" }, { "name": "PF-05221304", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 75, "start_date": "2020-08-10", "completion_date": "2022-04-28", "has_results": true, "last_update_posted_date": "2023-04-13", "last_synced_at": "2026-09-13T01:30:25.138Z", "location_count": 11, "location_summary": "Lincoln, California • Montclair, California • Boca Raton, Florida + 7 more", "locations": [ { "city": "Lincoln", "state": "California" }, { "city": "Montclair", "state": "California" }, { "city": "Boca Raton", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Miami Lakes", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04399538" } ] }