{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PGT121",
    "query": {
      "intervention": "PGT121"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-05T15:37:13.334Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04144335",
      "title": "N-803 Combined With the Broadly Neutralizing Antibodies Plus or Minus haNK Cells for HIV",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Hiv",
        "HIV/AIDS",
        "HIV Infections",
        "AIDS",
        "AIDS and Infections",
        "Aids/Hiv Problem"
      ],
      "interventions": [
        {
          "name": "N-803 and bNAbs",
          "type": "BIOLOGICAL"
        },
        {
          "name": "haNK™ Cells",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2020-01-01",
      "completion_date": "2020-12-31",
      "has_results": false,
      "last_update_posted_date": "2020-10-22",
      "last_synced_at": "2026-09-05T15:37:13.334Z",
      "location_count": 3,
      "location_summary": "San Francisco, California • Boston, Massachusetts • Minneapolis, Minnesota",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04144335"
    },
    {
      "nct_id": "NCT03721510",
      "title": "A Phase 1/2a Study of PGT121, VRC07-523LS and PGDM1400 Monoclonal Antibodies in HIV-uninfected and HIV-infected Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "HIV/AIDS"
      ],
      "interventions": [
        {
          "name": "PGT121 + VRC07-523LS",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PGT121 + VRC07-523LS + PGDM1400",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "International AIDS Vaccine Initiative",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 19,
      "start_date": "2018-12-03",
      "completion_date": "2022-05-02",
      "has_results": false,
      "last_update_posted_date": "2022-05-10",
      "last_synced_at": "2026-09-05T15:37:13.334Z",
      "location_count": 3,
      "location_summary": "Orlando, Florida • Boston, Massachusetts • Houston, Texas",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03721510"
    },
    {
      "nct_id": "NCT03928821",
      "title": "Evaluating the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Combinations of Monoclonal Antibodies PGT121, PGDM1400, 10-1074, and VRC07-523LS Administered Via Intravenous Infusion in Healthy, HIV-uninfected Adult Participants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "PGT121",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PGDM1400",
          "type": "BIOLOGICAL"
        },
        {
          "name": "10-1074",
          "type": "BIOLOGICAL"
        },
        {
          "name": "VRC07-523LS",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 27,
      "start_date": "2019-07-17",
      "completion_date": "2021-03-25",
      "has_results": true,
      "last_update_posted_date": "2022-07-11",
      "last_synced_at": "2026-09-05T15:37:13.334Z",
      "location_count": 4,
      "location_summary": "Boston, Massachusetts • New York, New York • Nashville, Tennessee",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03928821"
    },
    {
      "nct_id": "NCT02960581",
      "title": "Safety, PK and Antiviral Activity of PGT121 Monoclonal Antibody in HIV-uninfected and HIV-infected Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "HIV Infection"
      ],
      "interventions": [
        {
          "name": "PGT121 3mg/kg IV",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PGT121 10mg/kg IV",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PGT121 30mg/kg IV",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PGT121 3mg/kg SC",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo (0.9% Sodium Chloride Injection USP (Saline))",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "International AIDS Vaccine Initiative",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 48,
      "start_date": "2016-11",
      "completion_date": "2019-07-08",
      "has_results": false,
      "last_update_posted_date": "2019-09-17",
      "last_synced_at": "2026-09-05T15:37:13.334Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02960581"
    },
    {
      "nct_id": "NCT04983030",
      "title": "Safety, Immunogenicity, Efficacy of Ad26.Mos4.HIV, MVA-BN-HIV and PGT121, PGDM1400, and VRC07-523LS in HIV-1-Infected Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "HIV",
        "Acquired Immunodeficiency Syndrome",
        "Immunologic Deficiency Syndrome, Acquired",
        "Sexually Transmitted Diseases, Viral",
        "Retroviridae Infections"
      ],
      "interventions": [
        {
          "name": "Ad26.Mos4.HIV",
          "type": "BIOLOGICAL"
        },
        {
          "name": "MVA-BN-HIV",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PGT121",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PGDM1400",
          "type": "BIOLOGICAL"
        },
        {
          "name": "VRC07-523LS",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Boris Juelg, MD PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 28,
      "start_date": "2022-04-01",
      "completion_date": "2026-02-23",
      "has_results": false,
      "last_update_posted_date": "2026-05-29",
      "last_synced_at": "2026-09-05T15:37:13.334Z",
      "location_count": 6,
      "location_summary": "Los Angeles, California • Orlando, Florida • Boston, Massachusetts + 3 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04983030"
    },
    {
      "nct_id": "NCT03205917",
      "title": "A Clinical Trial of PGDM1400 and PGT121 and VRC07-523LS Monoclonal Antibodies in HIV-infected and HIV-uninfected Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "PGDM1400/Placebo (3mg/kg IV)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PGDM1400/Placebo (10mg/kg IV)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PGDM1400/Placebo (30mg/kg IV)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PGDM1400 + PGT121/Placebo (3mg/kg + 3mg/kg IV)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PGDM1400 + PGT121/Placebo (10mg/kg + 10mg/kg IV)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PGDM1400 + PGT121/Placebo (30mg/kg + 30mg/kg IV)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PGDM1400 + PGT121 + VRC07-523LS (20mg/kg + 20mg/kg + 20 mg/kg IV)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PGDM1400 + PGT121 (MTD IV)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "International AIDS Vaccine Initiative",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 29,
      "start_date": "2017-10-23",
      "completion_date": "2020-04-20",
      "has_results": false,
      "last_update_posted_date": "2020-09-14",
      "last_synced_at": "2026-09-05T15:37:13.334Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03205917"
    }
  ]
}