{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PM2.5",
    "query": {
      "intervention": "PM2.5"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PM2.5&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-12T02:27:51.344Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05718245",
      "title": "HEPA, PM2.5, and Cardiometabolic Health",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Air Pollution",
        "Cardiometabolic Health"
      ],
      "interventions": [
        {
          "name": "HEPA filter",
          "type": "DEVICE"
        },
        {
          "name": "Sham filter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "65 Years to 84 Years"
      },
      "enrollment_count": 52,
      "start_date": "2023-03-15",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-08-01",
      "last_synced_at": "2026-09-12T02:27:51.344Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05718245"
    },
    {
      "nct_id": "NCT05867381",
      "title": "Using Indoor Air Filtration to Slow Atherothrombosis Progression in Adults With Ischemic Heart Disease History",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Air Pollution",
        "Atherosclerosis"
      ],
      "interventions": [
        {
          "name": "HEPA filtration",
          "type": "DEVICE"
        },
        {
          "name": "Sham filtration",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "65 Years to 84 Years"
      },
      "enrollment_count": 112,
      "start_date": "2023-07-11",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-08",
      "last_synced_at": "2026-09-12T02:27:51.344Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05867381"
    },
    {
      "nct_id": "NCT05323240",
      "title": "Health Effects of Repeated Exposure to Low Levels of Concentrated Ambient Particles in Healthy Young Volunteers",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Air Pollution"
      ],
      "interventions": [
        {
          "name": "PM exposure",
          "type": "OTHER"
        },
        {
          "name": "Filtered air exposure",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "U.S. EPA Human Studies Facility",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 20,
      "start_date": "2022-05-12",
      "completion_date": "2025-12-20",
      "has_results": false,
      "last_update_posted_date": "2023-11-28",
      "last_synced_at": "2026-09-12T02:27:51.344Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05323240"
    },
    {
      "nct_id": "NCT07539987",
      "title": "Evaluation of a Novel Indoor Air Pollution Intervention Among Older Adults",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Diseases",
        "Blood Pressure",
        "Glycated Hemoglobin (HbA1c)",
        "Cholesterol",
        "Cholesterol, HDL",
        "Cholesterol, LDL",
        "Indoor Air Quality",
        "Particulate Matter",
        "Health Behavior"
      ],
      "interventions": [
        {
          "name": "Air Improvement and Real-time Monitoring for Wellness through Interactive Strategies and Education (AIRWISE)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Portable Air Cleaner (PAC) Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Montana",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "55 Years to 79 Years"
      },
      "enrollment_count": 154,
      "start_date": "2026-08",
      "completion_date": "2030-07",
      "has_results": false,
      "last_update_posted_date": "2026-04-20",
      "last_synced_at": "2026-09-12T02:27:51.344Z",
      "location_count": 1,
      "location_summary": "Missoula, Montana",
      "locations": [
        {
          "city": "Missoula",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07539987"
    },
    {
      "nct_id": "NCT04955431",
      "title": "Circadian Rhythm Disruption Effects on Smoke Inhalation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Inflammation",
        "Sleep Deprivation",
        "Circadian Rhythm Sleep Disorder, Shift Work Type",
        "Smoke Inhalation"
      ],
      "interventions": [
        {
          "name": "Sleep Restriction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Normal Sleep",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Montana",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "44 Years",
        "sex": "MALE",
        "summary": "18 Years to 44 Years · Male only"
      },
      "enrollment_count": 10,
      "start_date": "2022-01-24",
      "completion_date": "2022-04-17",
      "has_results": true,
      "last_update_posted_date": "2025-05-30",
      "last_synced_at": "2026-09-12T02:27:51.344Z",
      "location_count": 1,
      "location_summary": "Missoula, Montana",
      "locations": [
        {
          "city": "Missoula",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04955431"
    },
    {
      "nct_id": "NCT00044603",
      "title": "Vulnerability of the Fetus/Infant to PAH, PM2.5 AND ETS.",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pregnancy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Environmental Health Sciences (NIEHS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 505,
      "start_date": "2000-02",
      "completion_date": "2006-01",
      "has_results": false,
      "last_update_posted_date": "2014-10-15",
      "last_synced_at": "2026-09-12T02:27:51.344Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00044603"
    },
    {
      "nct_id": "NCT04563052",
      "title": "Measuring Knowledge and Behavior After an Educational Program on Air Pollution as a Health Risk Reduction Strategy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Air Pollution, Risk Reduction Behaviors"
      ],
      "interventions": [
        {
          "name": "Educational Program on Air Pollution as a Health Risk Reduction Strategy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Villanova University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2020-01-28",
      "completion_date": "2021-02-15",
      "has_results": false,
      "last_update_posted_date": "2021-02-17",
      "last_synced_at": "2026-09-12T02:27:51.344Z",
      "location_count": 1,
      "location_summary": "Villanova, Pennsylvania",
      "locations": [
        {
          "city": "Villanova",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04563052"
    },
    {
      "nct_id": "NCT03232086",
      "title": "Responses to Exposure to Low Levels of Concentrated Ambient Particles in Healthy Young Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Exposure to Pollution"
      ],
      "interventions": [
        {
          "name": "Clean Air",
          "type": "OTHER"
        },
        {
          "name": "PM2.5",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Environmental Protection Agency (EPA)",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 20,
      "start_date": "2017-01-16",
      "completion_date": "2020-07-30",
      "has_results": false,
      "last_update_posted_date": "2021-09-05",
      "last_synced_at": "2026-09-12T02:27:51.344Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03232086"
    },
    {
      "nct_id": "NCT04549142",
      "title": "Immune Tolerance Dysfunction in Pregnancy Due to Ambient Air Pollution Exposure",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Air Pollution",
        "Pregnancy"
      ],
      "interventions": [
        {
          "name": "There is no intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 400,
      "start_date": "2020-08-01",
      "completion_date": "2023-06-12",
      "has_results": false,
      "last_update_posted_date": "2023-06-15",
      "last_synced_at": "2026-09-12T02:27:51.344Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04549142"
    },
    {
      "nct_id": "NCT07116460",
      "title": "Cost Effective Air Filtration Intervention in Low-Income Housing to Reduce Asthma Morbidity",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Asthma Attack",
        "Lung Function",
        "Airway Inflammation"
      ],
      "interventions": [
        {
          "name": "Austin Air Cleaner",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "7 Years to 18 Years"
      },
      "enrollment_count": 55,
      "start_date": "2026-01-30",
      "completion_date": "2028-04",
      "has_results": false,
      "last_update_posted_date": "2026-06-02",
      "last_synced_at": "2026-09-12T02:27:51.344Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07116460"
    }
  ]
}