{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PPSV-23",
    "query": {
      "intervention": "PPSV-23"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 244,
    "total_pages": 25,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PPSV-23&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-10T07:18:50.552Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07086677",
      "title": "A Study to Learn About How a New Pneumococcal Vaccine Works in Adults",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Streptococcus Pneumoniae"
      ],
      "interventions": [
        {
          "name": "PG4 vaccine in Buffer 1 with low dose PA-001",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PG4 in Buffer 1 with low dose PA-002",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PG4 in Buffer 1 with high dose PA-001",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PG4 vaccine in Buffer 1 with high dose PA-002",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PG4 vaccine in Buffer 2",
          "type": "BIOLOGICAL"
        },
        {
          "name": "20-valent pneumococcal conjugate vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Saline injection",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "65 Years to 84 Years"
      },
      "enrollment_count": 380,
      "start_date": "2025-07-22",
      "completion_date": "2027-10-21",
      "has_results": false,
      "last_update_posted_date": "2026-06-22",
      "last_synced_at": "2026-09-10T07:18:50.552Z",
      "location_count": 20,
      "location_summary": "Lake Forest, California • Rolling Hills Estates, California • Greenacres City, Florida + 13 more",
      "locations": [
        {
          "city": "Lake Forest",
          "state": "California"
        },
        {
          "city": "Rolling Hills Estates",
          "state": "California"
        },
        {
          "city": "Greenacres City",
          "state": "Florida"
        },
        {
          "city": "Miami Lakes",
          "state": "Florida"
        },
        {
          "city": "Lenexa",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07086677"
    },
    {
      "nct_id": "NCT00500266",
      "title": "Study Evaluating Safety of 13-Valent Pneumococcal Conjugate Vaccine in Healthy Elderly Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pneumococcal Infections"
      ],
      "interventions": [
        {
          "name": "13-valent Pneumococcal Conjugate Vaccine (13vPnC)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "68 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "68 Years and older"
      },
      "enrollment_count": 1053,
      "start_date": "2008-05",
      "completion_date": "2009-05",
      "has_results": true,
      "last_update_posted_date": "2011-09-16",
      "last_synced_at": "2026-09-10T07:18:50.552Z",
      "location_count": 40,
      "location_summary": "Chandler, Arizona • Glendale, Arizona • Phoenix, Arizona + 33 more",
      "locations": [
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Glendale",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Rolling Hills Estates",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00500266"
    },
    {
      "nct_id": "NCT00483574",
      "title": "Study of the Safety of Menactra® Vaccine When Administered With Other Pediatric Vaccines to Healthy Toddlers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Meningococcal Meningitis",
        "Measles",
        "Mumps",
        "Rubella",
        "Varicella"
      ],
      "interventions": [
        {
          "name": "Menactra®: Meningococcal Polysaccharide Diphtheria Toxoid Conjugate",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Measles-mumps-rubella-varicella vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Routine paediatric vaccine - Pneumococcal conjugate (PCV)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Routine paediatric vaccine - Hepatitis A",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Sanofi Pasteur, a Sanofi Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "9 Months",
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "9 Months to 12 Months"
      },
      "enrollment_count": 1378,
      "start_date": "2007-05",
      "completion_date": "2009-04",
      "has_results": true,
      "last_update_posted_date": "2016-05-16",
      "last_synced_at": "2026-09-10T07:18:50.552Z",
      "location_count": 78,
      "location_summary": "Birmingham, Alabama • Dothan, Alabama • Pinson, Alabama + 68 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Dothan",
          "state": "Alabama"
        },
        {
          "city": "Pinson",
          "state": "Alabama"
        },
        {
          "city": "Tuscaloosa",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00483574"
    },
    {
      "nct_id": "NCT00334607",
      "title": "Study of 2 Doses of HRV Vaccine Given Concomitantly or Separately With Routine Vaccinations in Healthy Infants in USA",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Infections, Rotavirus"
      ],
      "interventions": [
        {
          "name": "2-dose oral live attenuated G1P[8] human rotavirus vaccine",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Weeks",
        "maximum_age": "16 Weeks",
        "sex": "ALL",
        "summary": "6 Weeks to 16 Weeks"
      },
      "enrollment_count": 484,
      "start_date": "2006-06",
      "completion_date": "2007-06",
      "has_results": false,
      "last_update_posted_date": "2016-11-04",
      "last_synced_at": "2026-09-10T07:18:50.552Z",
      "location_count": 42,
      "location_summary": "Benton, Arkansas • Cabot, Arkansas • Jonesboro, Arkansas + 37 more",
      "locations": [
        {
          "city": "Benton",
          "state": "Arkansas"
        },
        {
          "city": "Cabot",
          "state": "Arkansas"
        },
        {
          "city": "Jonesboro",
          "state": "Arkansas"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "North Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00334607"
    },
    {
      "nct_id": "NCT07660198",
      "title": "Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pneumococcal Disease"
      ],
      "interventions": [
        {
          "name": "PG4",
          "type": "BIOLOGICAL"
        },
        {
          "name": "20-valent pneumococcal conjugate vaccine (20vPnC)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "15 Months",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "15 Months to 17 Years"
      },
      "enrollment_count": 1200,
      "start_date": "2026-06-15",
      "completion_date": "2027-12-02",
      "has_results": false,
      "last_update_posted_date": "2026-08-31",
      "last_synced_at": "2026-09-10T07:18:50.552Z",
      "location_count": 57,
      "location_summary": "Birmingham, Alabama • Guntersville, Alabama • Fair Oaks, California + 37 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Guntersville",
          "state": "Alabama"
        },
        {
          "city": "Fair Oaks",
          "state": "California"
        },
        {
          "city": "Ontario",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07660198"
    },
    {
      "nct_id": "NCT05028634",
      "title": "Safety Study to Evaluate Immune Response of Vaccines in Participants With Relapsing Forms of Multiple Sclerosis Who Receive Ozanimod Compared to Non-Pegylated Interferon (IFN)-β or No Disease Modifying Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Multiple Sclerosis",
        "Multiple Sclerosis, Relapsing-Remitting"
      ],
      "interventions": [
        {
          "name": "Tetanus, diphtheria, and acellular pertussis vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Pneumococcal polysaccharide vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Seasonal influenza vaccine",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Celgene",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 63,
      "start_date": "2021-11-11",
      "completion_date": "2023-11-15",
      "has_results": true,
      "last_update_posted_date": "2025-02-11",
      "last_synced_at": "2026-09-10T07:18:50.552Z",
      "location_count": 29,
      "location_summary": "Palo Alto, California • Colorado Springs, Colorado • Southington, Connecticut + 26 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        },
        {
          "city": "Southington",
          "state": "Connecticut"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Port Charlotte",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05028634"
    },
    {
      "nct_id": "NCT00743652",
      "title": "Study Evaluating the Impact of the 13-valent Pneumococcal Conjugate Vaccine (13vPnC) in Alaskan Native Children.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pneumococcal Disease",
        "13-valent Pneumococcal Vaccine"
      ],
      "interventions": [
        {
          "name": "13-valent Pneumococcal Conjugate Vaccine",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "42 Days",
        "maximum_age": "5 Years",
        "sex": "ALL",
        "summary": "42 Days to 5 Years"
      },
      "enrollment_count": 373,
      "start_date": "2009-01",
      "completion_date": "2010-09",
      "has_results": true,
      "last_update_posted_date": "2012-03-15",
      "last_synced_at": "2026-09-10T07:18:50.552Z",
      "location_count": 21,
      "location_summary": "Akiak, Alaska • Bethel, Alaska • Chefornak, Alaska + 18 more",
      "locations": [
        {
          "city": "Akiak",
          "state": "Alaska"
        },
        {
          "city": "Bethel",
          "state": "Alaska"
        },
        {
          "city": "Chefornak",
          "state": "Alaska"
        },
        {
          "city": "Chevak",
          "state": "Alaska"
        },
        {
          "city": "Eek",
          "state": "Alaska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00743652"
    },
    {
      "nct_id": "NCT05420961",
      "title": "A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V116 in Pneumococcal Vaccine-experienced Adults (V116-006, STRIDE-6)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pneumonia, Pneumococcal"
      ],
      "interventions": [
        {
          "name": "V116",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PCV15",
          "type": "BIOLOGICAL"
        },
        {
          "name": "PPSV23",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Merck Sharp & Dohme LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 717,
      "start_date": "2022-07-12",
      "completion_date": "2023-05-16",
      "has_results": true,
      "last_update_posted_date": "2024-10-26",
      "last_synced_at": "2026-09-10T07:18:50.552Z",
      "location_count": 15,
      "location_summary": "Birmingham, Alabama • Glendale, Arizona • Tempe, Arizona + 12 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Glendale",
          "state": "Arizona"
        },
        {
          "city": "Tempe",
          "state": "Arizona"
        },
        {
          "city": "Fountain Valley",
          "state": "California"
        },
        {
          "city": "Walnut Creek",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05420961"
    },
    {
      "nct_id": "NCT02654704",
      "title": "Vaccination Responses in Young and Older Adults",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Individuality",
        "Healthy",
        "Asthma",
        "Immune System and Related Disorders"
      ],
      "interventions": [
        {
          "name": "Pneumococcal Vaccination",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Michigan State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 61,
      "start_date": "2015-11",
      "completion_date": "2020-07",
      "has_results": false,
      "last_update_posted_date": "2020-07-29",
      "last_synced_at": "2026-09-10T07:18:50.552Z",
      "location_count": 1,
      "location_summary": "East Lansing, Michigan",
      "locations": [
        {
          "city": "East Lansing",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02654704"
    },
    {
      "nct_id": "NCT00133549",
      "title": "9-valent CRM 197 Pneumococcal",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pneumococcal Infection"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "PNU-IMUNE®23",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Nine-valent pneumococcal conjugate (PNCRM9)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BIOLOGICAL"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 180,
      "start_date": "2000-11",
      "completion_date": "2002-12",
      "has_results": false,
      "last_update_posted_date": "2014-10-17",
      "last_synced_at": "2026-09-10T07:18:50.552Z",
      "location_count": 2,
      "location_summary": "Rochester, New York • Cincinnati, Ohio",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00133549"
    }
  ]
}