{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PREMARIN&page=2",
    "query": {
      "intervention": "PREMARIN",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PREMARIN&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-25T02:18:26.451Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03943823",
      "title": "Postmenopausal Pessary Users: Estrogen Versus Trimosan",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Vaginosis",
        "Vaginosis, Bacterial",
        "Vaginal Discharge"
      ],
      "interventions": [
        {
          "name": "Estrogen vaginal cream",
          "type": "DRUG"
        },
        {
          "name": "Trimo-San vaginal gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "40 Years and older · Female only"
      },
      "enrollment_count": 4,
      "start_date": "2019-05-07",
      "completion_date": "2021-04-08",
      "has_results": true,
      "last_update_posted_date": "2023-03-08",
      "last_synced_at": "2026-09-25T02:18:26.451Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03943823"
    },
    {
      "nct_id": "NCT00242710",
      "title": "Study Evaluating Bazedoxifene/Conjugated Estrogens Combinations In Postmenopausal Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Endometrial Hyperplasia",
        "Osteoporosis"
      ],
      "interventions": [
        {
          "name": "Bazedoxifene/Conjugated Estrogen",
          "type": "DRUG"
        },
        {
          "name": "CE 0.45 mg/MPA 1.5mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 65 Years · Female only"
      },
      "enrollment_count": 1083,
      "start_date": "2005-09",
      "completion_date": "2008-09",
      "has_results": true,
      "last_update_posted_date": "2013-12-20",
      "last_synced_at": "2026-09-25T02:18:26.451Z",
      "location_count": 9,
      "location_summary": "Upland, California • Inverness, Florida • West Palm Beach, Florida + 6 more",
      "locations": [
        {
          "city": "Upland",
          "state": "California"
        },
        {
          "city": "Inverness",
          "state": "Florida"
        },
        {
          "city": "West Palm Beach",
          "state": "Florida"
        },
        {
          "city": "Decatur",
          "state": "Georgia"
        },
        {
          "city": "Honolulu",
          "state": "Hawaii"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00242710"
    },
    {
      "nct_id": "NCT00706225",
      "title": "Study Evaluating Potential Drug Interaction Of Bazedoxifene & Premarin In Healthy Postmenopausal Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Postmenopause"
      ],
      "interventions": [
        {
          "name": "Bazedoxifene and conjugated estrogens",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wyeth is now a wholly owned subsidiary of Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 70 Years · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2008-06",
      "completion_date": "2008-07",
      "has_results": false,
      "last_update_posted_date": "2010-09-23",
      "last_synced_at": "2026-09-25T02:18:26.451Z",
      "location_count": 1,
      "location_summary": "Daytona Beach, Florida",
      "locations": [
        {
          "city": "Daytona Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00706225"
    },
    {
      "nct_id": "NCT02524561",
      "title": "KEEPS Mammographic Density And Breast Health Ancillary Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mammographic Density",
        "Abnormal Mammogram"
      ],
      "interventions": [
        {
          "name": "CEE pill",
          "type": "DRUG"
        },
        {
          "name": "Estradiol patch",
          "type": "DRUG"
        },
        {
          "name": "Active Progesterone",
          "type": "DRUG"
        },
        {
          "name": "Placebo tablet",
          "type": "OTHER"
        },
        {
          "name": "Placebo patch",
          "type": "OTHER"
        },
        {
          "name": "Placebo progesterone",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "42 Years",
        "maximum_age": "58 Years",
        "sex": "FEMALE",
        "summary": "42 Years to 58 Years · Female only"
      },
      "enrollment_count": 517,
      "start_date": "2005-09",
      "completion_date": "2013-12",
      "has_results": true,
      "last_update_posted_date": "2017-03-08",
      "last_synced_at": "2026-09-25T02:18:26.451Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02524561"
    },
    {
      "nct_id": "NCT00167921",
      "title": "Study Comparing Premarin® Vaginal Cream Versus Premarin® Oral Tablets in Atrophic Vaginitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Atrophic Vaginitis"
      ],
      "interventions": [
        {
          "name": "Premarin® Vaginal Cream",
          "type": "DRUG"
        },
        {
          "name": "Premarin® oral tablets",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wyeth is now a wholly owned subsidiary of Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "80 Years",
        "sex": "FEMALE",
        "summary": "45 Years to 80 Years · Female only"
      },
      "enrollment_count": 24,
      "start_date": "2005-10",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2007-05-28",
      "last_synced_at": "2026-09-25T02:18:26.451Z",
      "location_count": 2,
      "location_summary": "Miami, Florida • Baltimore, Maryland",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00167921"
    },
    {
      "nct_id": "NCT02710214",
      "title": "A TSEC for Symptom Management in Menopausal Women With Multiple Sclerosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Menopause",
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "Tissue Selective Estrogen Complex",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "62 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 62 Years · Female only"
      },
      "enrollment_count": 24,
      "start_date": "2016-02",
      "completion_date": "2019-04-24",
      "has_results": true,
      "last_update_posted_date": "2020-07-15",
      "last_synced_at": "2026-09-25T02:18:26.451Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02710214"
    },
    {
      "nct_id": "NCT01613170",
      "title": "Premarin Versus Toviaz for Treatment of Overactive Bladder",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Overactive Bladder"
      ],
      "interventions": [
        {
          "name": "Toviaz",
          "type": "DRUG"
        },
        {
          "name": "Premarin",
          "type": "DRUG"
        },
        {
          "name": "Placebo cream",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "100 Years",
        "sex": "FEMALE",
        "summary": "30 Years to 100 Years · Female only"
      },
      "enrollment_count": 90,
      "start_date": "2012-04",
      "completion_date": "2018-12",
      "has_results": false,
      "last_update_posted_date": "2017-04-20",
      "last_synced_at": "2026-09-25T02:18:26.451Z",
      "location_count": 1,
      "location_summary": "Weston, Florida",
      "locations": [
        {
          "city": "Weston",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01613170"
    },
    {
      "nct_id": "NCT01648751",
      "title": "Vaginal Estrogen and Pelvic Floor Physical Therapy in Women With Symptomatic Mild Prolapse",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pelvic Organ Prolapse"
      ],
      "interventions": [
        {
          "name": "Vaginal estrogen",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pamela Moalli",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 80 Years · Female only"
      },
      "enrollment_count": 21,
      "start_date": "2012-05",
      "completion_date": "2023-03-02",
      "has_results": true,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-09-25T02:18:26.451Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01648751"
    },
    {
      "nct_id": "NCT01634789",
      "title": "A Pilot Bioavailability Study of 3 Test Tablet Formulations of Bazedoxifene Compared With A Reference Tablet Formulation of Bazedoxifene/Conjugated Estrogens in Healthy Postmenopausal Women",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "bazedoxifene",
          "type": "DRUG"
        },
        {
          "name": "bazedoxifene/conjugated estrogens",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "64 Years",
        "sex": "FEMALE",
        "summary": "45 Years to 64 Years · Female only"
      },
      "enrollment_count": 2,
      "start_date": "2012-08",
      "completion_date": "2012-11",
      "has_results": false,
      "last_update_posted_date": "2013-01-18",
      "last_synced_at": "2026-09-25T02:18:26.451Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01634789"
    },
    {
      "nct_id": "NCT02835846",
      "title": "Investigation of the Effect of the Female Urinary Microbiome on Incontinence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Overactive Bladder",
        "Incontinence",
        "Nocturia"
      ],
      "interventions": [
        {
          "name": "Estrogen Cream",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Loyola University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 35,
      "start_date": "2016-09",
      "completion_date": "2018-05",
      "has_results": true,
      "last_update_posted_date": "2021-09-23",
      "last_synced_at": "2026-09-25T02:18:26.451Z",
      "location_count": 1,
      "location_summary": "Maywood, Illinois",
      "locations": [
        {
          "city": "Maywood",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02835846"
    }
  ]
}