{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PRIME&page=25", "query": { "intervention": "PRIME", "page": 25 }, "page_size": 10 }, "pagination": { "page": 25, "page_size": 10, "total_count": 593, "total_pages": 60, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PRIME&page=26&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PRIME&page=24&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-28T17:36:42.974Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01729845", "title": "Decitabine Followed by Mitoxantrone Hydrochloride, Etoposide, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Previously Treated Myelodysplastic Syndrome", "Recurrent Adult Acute Myeloid Leukemia" ], "interventions": [ { "name": "Cytarabine", "type": "DRUG" }, { "name": "Decitabine", "type": "DRUG" }, { "name": "Etoposide", "type": "DRUG" }, { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Mitoxantrone Hydrochloride", "type": "DRUG" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Fred Hutchinson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 52, "start_date": "2012-12-20", "completion_date": "2017-04-03", "has_results": true, "last_update_posted_date": "2019-02-07", "last_synced_at": "2026-10-28T17:36:42.974Z", "location_count": 3, "location_summary": "Kennewick, Washington • Kirkland, Washington • Seattle, Washington", "locations": [ { "city": "Kennewick", "state": "Washington" }, { "city": "Kirkland", "state": "Washington" }, { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT01729845" }, { "nct_id": "NCT04108481", "title": "Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Colorectal Cancer Metastatic", "Colon Cancer", "Metastatic Colorectal Cancer", "Rectal Cancer", "Liver Metastasis Colon Cancer", "Colo-rectal Cancer", "Colorectal Adenocarcinoma", "Colorectal Neoplasms", "Liver Metastases", "Colorectal Carcinoma" ], "interventions": [ { "name": "Durvalumab", "type": "DRUG" }, { "name": "Yttrium-90 RadioEmbolization", "type": "RADIATION" } ], "intervention_types": [ "DRUG", "RADIATION" ], "sponsor": "University of Iowa", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 5, "start_date": "2020-10-05", "completion_date": "2023-11-17", "has_results": false, "last_update_posted_date": "2025-03-28", "last_synced_at": "2026-10-28T17:36:42.974Z", "location_count": 1, "location_summary": "Iowa City, Iowa", "locations": [ { "city": "Iowa City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT04108481" }, { "nct_id": "NCT00472719", "title": "Safety of and Immune Response to a DNA HIV Vaccine Followed By Boosting With One of Two Serotypes of Adenoviral Vector HIV Vaccine in Healthy Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "HIV Infections" ], "interventions": [ { "name": "VRC-HIVADV027-00-VP", "type": "BIOLOGICAL" }, { "name": "VRC-HIVADV038-00-VP", "type": "BIOLOGICAL" }, { "name": "VRC-HIVDNA044-00-VP", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 17, "start_date": "2007-08", "completion_date": "2013-01", "has_results": false, "last_update_posted_date": "2021-10-14", "last_synced_at": "2026-10-28T17:36:42.974Z", "location_count": 7, "location_summary": "Birmingham, Alabama • San Francisco, California • New York, New York + 3 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "San Francisco", "state": "California" }, { "city": "New York", "state": "New York" }, { "city": "New York", "state": "New York" }, { "city": "Rochester", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00472719" }, { "nct_id": "NCT05099328", "title": "Recasting or Book Reading by Parents or Clinicians", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Developmental Language Disorder and Language Impairment" ], "interventions": [ { "name": "Recast Therapy", "type": "BEHAVIORAL" }, { "name": "Syntax Stories", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Delaware", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "4 Years", "maximum_age": "9 Years", "sex": "ALL", "summary": "4 Years to 9 Years" }, "enrollment_count": 137, "start_date": "2021-09-28", "completion_date": "2026-04-20", "has_results": false, "last_update_posted_date": "2026-05-12", "last_synced_at": "2026-10-28T17:36:42.974Z", "location_count": 2, "location_summary": "Newark, Delaware • College Park, Maryland", "locations": [ { "city": "Newark", "state": "Delaware" }, { "city": "College Park", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT05099328" }, { "nct_id": "NCT04108130", "title": "An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Postoperative Pulmonary Complications" ], "interventions": [ { "name": "Preoperative Education", "type": "OTHER" }, { "name": "Intraoperative PEEP (Positive End-Expiratory Pressure) Individualization", "type": "PROCEDURE" }, { "name": "Individualization of Neuromuscular Blockade", "type": "OTHER" }, { "name": "Postoperative Incentive Spirometry", "type": "PROCEDURE" }, { "name": "Postoperative Ambulation", "type": "BEHAVIORAL" } ], "intervention_types": [ "OTHER", "PROCEDURE", "BEHAVIORAL" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 794, "start_date": "2020-01-29", "completion_date": "2023-07-13", "has_results": true, "last_update_posted_date": "2025-10-06", "last_synced_at": "2026-10-28T17:36:42.974Z", "location_count": 16, "location_summary": "San Francisco, California • Stanford, California • Aurora, Colorado + 10 more", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Stanford", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Miami", "state": "Florida" }, { "city": "Evanston", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT04108130" }, { "nct_id": "NCT04477330", "title": "Cortical Priming to Optimize Gait Rehabilitation in Stroke: a Renewal", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Stroke" ], "interventions": [ { "name": "Transcranial direct current stimulation (tDCS)", "type": "OTHER" }, { "name": "Ankle motor training", "type": "OTHER" }, { "name": "High intensity interval speed based treadmill training (HIISTT)", "type": "BEHAVIORAL" } ], "intervention_types": [ "OTHER", "BEHAVIORAL" ], "sponsor": "University of Illinois at Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100, "start_date": "2020-09-01", "completion_date": "2027-08-31", "has_results": false, "last_update_posted_date": "2026-05-11", "last_synced_at": "2026-10-28T17:36:42.974Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT04477330" }, { "nct_id": "NCT00479999", "title": "Phase 1 Safety Study of Two Experimental HIV Vaccines", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "AIDS Vaccines", "HIV Infections", "HIV-1" ], "interventions": [ { "name": "VRC-HIVADV027-00-VP", "type": "DRUG" }, { "name": "VRC-HIVADV038-00-VP", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 35, "start_date": "2007-05-24", "completion_date": "2014-05-05", "has_results": false, "last_update_posted_date": "2019-12-16", "last_synced_at": "2026-10-28T17:36:42.974Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00479999" }, { "nct_id": "NCT02277392", "title": "A Phase-I, Dose Escalation Study of Recombinant Human Interleukin-18 (Sb-485232) Combined With Adoptive Transfer of Vaccine-Primed CD3/CD28-Costimulated Autologous T-Cells Following Lymphodepletion for Adult Patients With Recurrent Ovarian, Fallopian Tube or Primary Peritoneal Cancer", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Ovarian, Fallopian Tube and Peritoneal Cancer" ], "interventions": [ { "name": "Vaccine---primed, CD3/CD28---costimulated autologous peripheral blood T---cells", "type": "BIOLOGICAL" }, { "name": "SB---485232 (Human recombinant Interleukin---18)", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Abramson Cancer Center at Penn Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 0, "start_date": "2014-09", "completion_date": null, "has_results": false, "last_update_posted_date": "2018-09-27", "last_synced_at": "2026-10-28T17:36:42.974Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02277392" }, { "nct_id": "NCT01164553", "title": "Comparison of Flu Vaccine Doses in Children", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Influenza" ], "interventions": [ { "name": "Trivalent Inactivated Influenza Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "6 Months", "maximum_age": "35 Months", "sex": "ALL", "summary": "6 Months to 35 Months" }, "enrollment_count": 243, "start_date": "2010-10", "completion_date": "2012-10", "has_results": false, "last_update_posted_date": "2013-04-29", "last_synced_at": "2026-10-28T17:36:42.974Z", "location_count": 7, "location_summary": "Atlanta, Georgia • Iowa City, Iowa • Baltimore, Maryland + 3 more", "locations": [ { "city": "Atlanta", "state": "Georgia" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Iowa City", "state": "Iowa" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT01164553" }, { "nct_id": "NCT05898022", "title": "Pragmatic Research on Diuretic Management in Early BPD Pilot", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Bronchopulmonary Dysplasia" ], "interventions": [ { "name": "Furosemide (plus potassium chloride)", "type": "DRUG" }, { "name": "Placebo (plus placebo electrolyte solution)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Children's Hospital Medical Center, Cincinnati", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "2 Weeks", "maximum_age": "10 Weeks", "sex": "ALL", "summary": "2 Weeks to 10 Weeks" }, "enrollment_count": 19, "start_date": "2023-08-17", "completion_date": "2025-12-12", "has_results": true, "last_update_posted_date": "2026-07-14", "last_synced_at": "2026-10-28T17:36:42.974Z", "location_count": 4, "location_summary": "Atlanta, Georgia • Durham, North Carolina • Cincinnati, Ohio + 1 more", "locations": [ { "city": "Atlanta", "state": "Georgia" }, { "city": "Durham", "state": "North Carolina" }, { "city": "Cincinnati", "state": "Ohio" }, { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT05898022" } ] }