{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PROMIS+depression",
    "query": {
      "intervention": "PROMIS depression"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 36,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PROMIS+depression&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-02T13:24:11.032Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04688554",
      "title": "Psychosocial, Behavioral, and Radiologic Changes Following Radiosurgery for Benign Neurologic Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Obsessive-Compulsive Disorder",
        "Pain, Intractable",
        "Depression"
      ],
      "interventions": [
        {
          "name": "fMRI and DTI",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Behavioral questionnaires",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Disease-Specific Patient-Reported Outcomes",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Behavioral tests",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "BEHAVIORAL"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2020-08-25",
      "completion_date": "2024-02-01",
      "has_results": false,
      "last_update_posted_date": "2024-12-06",
      "last_synced_at": "2026-09-02T13:24:11.032Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04688554"
    },
    {
      "nct_id": "NCT02574897",
      "title": "The Ability of Electronic Patient Symptom Reporting to Reduce Symptom Burden During Hospitalization for Chemotherapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stem Cell Transplantation, Hematopoietic"
      ],
      "interventions": [
        {
          "name": "Electronic symptom survey",
          "type": "OTHER"
        },
        {
          "name": "Blinded Electronic Symptom Survey",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "UNC Lineberger Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 76,
      "start_date": "2014-07",
      "completion_date": "2017-09",
      "has_results": false,
      "last_update_posted_date": "2018-03-22",
      "last_synced_at": "2026-09-02T13:24:11.032Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02574897"
    },
    {
      "nct_id": "NCT06616363",
      "title": "Does a Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Nat hx With Its Numerous Co-morbidities?",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "POTS - Postural Orthostatic Tachycardia Syndrome"
      ],
      "interventions": [
        {
          "name": "Questionnaires to be competed",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Provide list of medication and lifetime events",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Use phone App to record new life events",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Will wear an activity monitor",
          "type": "DEVICE"
        },
        {
          "name": "Periodic 24-hour urine sodium check",
          "type": "OTHER"
        },
        {
          "name": "A fMRI scan",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "A bedside tilt test will be performed",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "IV placed to collect blood samples",
          "type": "OTHER"
        },
        {
          "name": "Stool Sample",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE",
        "OTHER",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "21 Years",
        "sex": "FEMALE",
        "summary": "12 Years to 21 Years · Female only"
      },
      "enrollment_count": 120,
      "start_date": "2024-05-29",
      "completion_date": "2028-07",
      "has_results": false,
      "last_update_posted_date": "2025-09-26",
      "last_synced_at": "2026-09-02T13:24:11.032Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06616363"
    },
    {
      "nct_id": "NCT03375216",
      "title": "Quantitative Sensory Testing in Chronic Pain Patients Undergoing Opioid Treatment and Opioid Tapering",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Analgesic Drug Dependence",
        "Sensory Deficit"
      ],
      "interventions": [
        {
          "name": "sensory testing (Heat, cold, and pressure)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Promis Survey",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "The University of Texas Medical Branch, Galveston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 43,
      "start_date": "2017-12-22",
      "completion_date": "2023-11-18",
      "has_results": false,
      "last_update_posted_date": "2024-02-13",
      "last_synced_at": "2026-09-02T13:24:11.032Z",
      "location_count": 1,
      "location_summary": "Galveston, Texas",
      "locations": [
        {
          "city": "Galveston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03375216"
    },
    {
      "nct_id": "NCT04092777",
      "title": "Building Infrastructure for Community Capacity in Accelerating Integrated Care",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mental Health"
      ],
      "interventions": [
        {
          "name": "Strong Minds",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced Usual Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1044,
      "start_date": "2019-08-30",
      "completion_date": "2023-11-16",
      "has_results": true,
      "last_update_posted_date": "2025-08-26",
      "last_synced_at": "2026-09-02T13:24:11.032Z",
      "location_count": 2,
      "location_summary": "Quincy, Massachusetts • Revere, Massachusetts",
      "locations": [
        {
          "city": "Quincy",
          "state": "Massachusetts"
        },
        {
          "city": "Revere",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04092777"
    },
    {
      "nct_id": "NCT05859386",
      "title": "Optimizing Mindfulness Based Cognitive Therapy (MBCT) Maintenance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression"
      ],
      "interventions": [
        {
          "name": "Mindfulness maintenance program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2023-04-03",
      "completion_date": "2024-02-19",
      "has_results": false,
      "last_update_posted_date": "2024-07-03",
      "last_synced_at": "2026-09-02T13:24:11.032Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05859386"
    },
    {
      "nct_id": "NCT02591472",
      "title": "An Integrated-Delivery-of-Care Approach to Improve Patient Outcomes, Safety, Well-Being After Orthopaedic Trauma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Musculoskeletal Injury Trauma"
      ],
      "interventions": [
        {
          "name": "Integrated care (ICare)",
          "type": "PROCEDURE"
        },
        {
          "name": "Usual Care (UsCare)",
          "type": "PROCEDURE"
        },
        {
          "name": "Patient-Reported Outcomes Measurement Information System",
          "type": "OTHER"
        },
        {
          "name": "Lower Extremity Gain Scale (LEGS)",
          "type": "OTHER"
        },
        {
          "name": "Dynamometer",
          "type": "OTHER"
        },
        {
          "name": "Active Range of Motion (AROM)",
          "type": "OTHER"
        },
        {
          "name": "Posttraumatic Stress Disorder (PTSD)",
          "type": "OTHER"
        },
        {
          "name": "Beck Depression Inventory-II",
          "type": "OTHER"
        },
        {
          "name": "State-Trait Anxiety Inventory (STAI)",
          "type": "OTHER"
        },
        {
          "name": "Tampa Scale of Kinesiophobia-11 (TSK-11)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 88,
      "start_date": "2016-01-11",
      "completion_date": "2023-01-01",
      "has_results": true,
      "last_update_posted_date": "2024-10-28",
      "last_synced_at": "2026-09-02T13:24:11.032Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02591472"
    },
    {
      "nct_id": "NCT06008574",
      "title": "A Study Comparing Mindfulness Apps to Decrease Anxiety in People With Lung Cancer",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lung Cancer"
      ],
      "interventions": [
        {
          "name": "AmDTx-PCSP",
          "type": "OTHER"
        },
        {
          "name": "AmDTx-2048",
          "type": "OTHER"
        },
        {
          "name": "Questionnaires",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2023-08-11",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2025-09-17",
      "last_synced_at": "2026-09-02T13:24:11.032Z",
      "location_count": 7,
      "location_summary": "Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more",
      "locations": [
        {
          "city": "Basking Ridge",
          "state": "New Jersey"
        },
        {
          "city": "Middletown",
          "state": "New Jersey"
        },
        {
          "city": "Montvale",
          "state": "New Jersey"
        },
        {
          "city": "Commack",
          "state": "New York"
        },
        {
          "city": "Harrison",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06008574"
    },
    {
      "nct_id": "NCT04319237",
      "title": "Axicabtagene Ciloleucel:Neurocognitive and Patient-Reported Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diffuse Large B Cell Lymphoma",
        "Transformed Lymphoma"
      ],
      "interventions": [
        {
          "name": "Handgrip strength test",
          "type": "OTHER"
        },
        {
          "name": "Neuropsychological Assessment - Wechsler Test of Adult Reading (WTAR)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Neuropsychological Assessment - Repeatable Battery for the Assessment of Status (RBANS)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Neuropsychological Assessment - Color Trails",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Neuropsychological Assessment -Stroop Color and Word Test",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Reported Outcomes Measurement Information System-29 (PROMIS-29) Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Quality of Life (EQ-5D-5L) Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "PROMIS Cognitive Function 4a Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Comprehensive Score for Financial Toxicity (COST) measure",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "H. Lee Moffitt Cancer Center and Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2020-03-10",
      "completion_date": "2023-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-02",
      "last_synced_at": "2026-09-02T13:24:11.032Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04319237"
    },
    {
      "nct_id": "NCT03383913",
      "title": "HRV-B for Symptom Management in Sickle Cell Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sickle Cell Disease"
      ],
      "interventions": [
        {
          "name": "Heart Rate Variability Biofeedback",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Prisma Health-Upstate",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "10 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2018-01-22",
      "completion_date": "2018-12-28",
      "has_results": false,
      "last_update_posted_date": "2024-10-28",
      "last_synced_at": "2026-09-02T13:24:11.032Z",
      "location_count": 1,
      "location_summary": "Greenville, South Carolina",
      "locations": [
        {
          "city": "Greenville",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03383913"
    }
  ]
}