{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PTSD+Reactivity+Condition",
    "query": {
      "intervention": "PTSD Reactivity Condition"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=PTSD+Reactivity+Condition&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-07T03:47:22.883Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06482567",
      "title": "Promoting Improved Functioning Among People Experiencing Stressful Situations",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Stress Reaction"
      ],
      "interventions": [
        {
          "name": "iCOVER",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Physical Presence with Reassurance",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 450,
      "start_date": "2024-08-15",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2025-12-09",
      "last_synced_at": "2026-09-07T03:47:22.883Z",
      "location_count": 5,
      "location_summary": "Belmont, Massachusetts • Worcester, Massachusetts • Detroit, Michigan + 2 more",
      "locations": [
        {
          "city": "Belmont",
          "state": "Massachusetts"
        },
        {
          "city": "Worcester",
          "state": "Massachusetts"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Camden",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06482567"
    },
    {
      "nct_id": "NCT00923923",
      "title": "Stress Reactivity in Veterans Receiving Pharmacological Treatment for PTSD and Alcohol Dependence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-traumatic Stress Disorder",
        "Alcohol Dependence"
      ],
      "interventions": [
        {
          "name": "stress",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 57,
      "start_date": "2009-01",
      "completion_date": "2015-07",
      "has_results": false,
      "last_update_posted_date": "2016-12-14",
      "last_synced_at": "2026-09-07T03:47:22.883Z",
      "location_count": 1,
      "location_summary": "West Haven, Connecticut",
      "locations": [
        {
          "city": "West Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00923923"
    },
    {
      "nct_id": "NCT03709199",
      "title": "Long Term Follow up of Children Enrolled in the REDvent Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Respiratory Distress Syndrome, Adult",
        "Ventilator-Induced Lung Injury",
        "Neurocognitive Dysfunction",
        "Quality of Life",
        "Respiration Disorders"
      ],
      "interventions": [
        {
          "name": "Ventilation Inhomogeneity",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Diaphragm Ultrasound",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Respiratory Inductance Plethysmography",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Spirometry",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Functional Residual Capacity",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "MIP/MEP",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "6 minute walk test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Neurocognitive Testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Emotional Health Assessment",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Health Related Quality of Life",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Functional Status",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Respiratory Status Questionnaire",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Children's Hospital Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "1 Month to 18 Years"
      },
      "enrollment_count": 176,
      "start_date": "2018-10-01",
      "completion_date": "2026-05-01",
      "has_results": false,
      "last_update_posted_date": "2025-04-17",
      "last_synced_at": "2026-09-07T03:47:22.883Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03709199"
    },
    {
      "nct_id": "NCT01271244",
      "title": "Effects of Escitalopram on Autonomic Reactivity in Post Traumatic Stress Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "PTSD"
      ],
      "interventions": [
        {
          "name": "Escitalopram",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "VA Nebraska Western Iowa Health Care System",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "19 Years to 55 Years"
      },
      "enrollment_count": 26,
      "start_date": "2008-06",
      "completion_date": "2013-06",
      "has_results": true,
      "last_update_posted_date": "2019-05-07",
      "last_synced_at": "2026-09-07T03:47:22.883Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01271244"
    },
    {
      "nct_id": "NCT01571245",
      "title": "Predicting Treatment Response Using Psychophysiologic Reactivity Measures",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Post Traumatic Stress Disorder"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Central Arkansas Veterans Healthcare System",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 9,
      "start_date": "2012-04",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2015-12-15",
      "last_synced_at": "2026-09-07T03:47:22.883Z",
      "location_count": 1,
      "location_summary": "North Little Rock, Arkansas",
      "locations": [
        {
          "city": "North Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01571245"
    },
    {
      "nct_id": "NCT01507948",
      "title": "Brain Imaging of Psychotherapy for Posttraumatic Stress Disorder (PTSD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Posttraumatic Stress Disorder (PTSD)"
      ],
      "interventions": [
        {
          "name": "Prolonged exposure",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 94,
      "start_date": "2010-09",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2017-01-23",
      "last_synced_at": "2026-09-07T03:47:22.883Z",
      "location_count": 2,
      "location_summary": "Palo Alto, California • Stanford, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01507948"
    },
    {
      "nct_id": "NCT01066156",
      "title": "Post-Traumatic Stress Disorder (PTSD) and Seroquel",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-Traumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Seroquel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cambridge Health Alliance",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 34,
      "start_date": "2010-02",
      "completion_date": "2015-03",
      "has_results": true,
      "last_update_posted_date": "2017-05-30",
      "last_synced_at": "2026-09-07T03:47:22.883Z",
      "location_count": 1,
      "location_summary": "Somerville, Massachusetts",
      "locations": [
        {
          "city": "Somerville",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01066156"
    },
    {
      "nct_id": "NCT04827056",
      "title": "Effect of Sublingual Formulation of Dexmedetomidine HCl (BXCL501) - Alcohol Interaction Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Alcohol Use Disorder (AUD)",
        "Post Traumatic Stress Disorder (PTSD)"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 40µg",
          "type": "DRUG"
        },
        {
          "name": "Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 80µg",
          "type": "DRUG"
        },
        {
          "name": "Ethanol Infusion",
          "type": "PROCEDURE"
        },
        {
          "name": "PTSD Reactivity Condition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Alcohol Cue Reactivity",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE",
        "BEHAVIORAL"
      ],
      "sponsor": "Pharmacotherapies for Alcohol and Substance Use Disorders Alliance",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 10,
      "start_date": "2021-11-09",
      "completion_date": "2023-06-02",
      "has_results": false,
      "last_update_posted_date": "2023-10-26",
      "last_synced_at": "2026-09-07T03:47:22.883Z",
      "location_count": 1,
      "location_summary": "West Haven, Connecticut",
      "locations": [
        {
          "city": "West Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04827056"
    },
    {
      "nct_id": "NCT04393623",
      "title": "Stress, Emotion Regulation, and Alcohol in Women Veterans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alcohol Use Disorder",
        "Post Traumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Cognitive Reappraisal",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Psychoeducation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 81,
      "start_date": "2020-11-01",
      "completion_date": "2024-09-30",
      "has_results": true,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-09-07T03:47:22.883Z",
      "location_count": 1,
      "location_summary": "Leeds, Massachusetts",
      "locations": [
        {
          "city": "Leeds",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04393623"
    },
    {
      "nct_id": "NCT02220309",
      "title": "Stanford RAD-AT Study (Research on Anxiety and Depression - Anhedonia Treatment)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Anxiety",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Pramipexole Oral Tablet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 167,
      "start_date": "2013-08-11",
      "completion_date": "2025-04-02",
      "has_results": false,
      "last_update_posted_date": "2026-01-05",
      "last_synced_at": "2026-09-07T03:47:22.883Z",
      "location_count": 3,
      "location_summary": "Los Altos, California • Palo Alto, California • Stanford, California",
      "locations": [
        {
          "city": "Los Altos",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02220309"
    }
  ]
}